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of 369
pro vyhledávání: ''
Autor:
Thomas Wolfram Paul Friedl, Wolfgang Janni, Davut Dayan, Amelie de Gregorio, Jens Huober, Nikolaus de Gregorio, Eva Hering, Peter Widschwendter, Inga Bekes
Publikováno v:
Oncology. 99:780-789
Introduction: Ki67 as a proliferative marker has prognostic and therapeutic relevance in early breast cancer (EBC). However, standard cutoffs for distinguishing low and high Ki67 do not exist. Material and Methods: Data from all patients treated at t
Autor:
Chia Che Wu, Meng Che Hsieh, Cheng-Hua Huang, Shih Yu Huang, Harvey Yu-Li Su, Po Hui Chiang, Chun-Chieh Huang, Kun Ming Rau, Jui Ming Liu, Hao Lun Luo, Ming Tse Sung
Publikováno v:
Oncology. 98:146-153
Objectives: Platinum-based chemotherapy is the standard treatment for metastatic urothelial carcinoma (mUC). However, considering elderly patients often experience comorbidities and frailty, the utility of cisplatin-based chemotherapy for elderly pat
Autor:
Francesca Platini, Alba Bianco, Carlo Resteghini, Donata Galbiati, Massimo Milione, Cristiana Bergamini, Paolo Bossi, Lisa Licitra, Salvatore Alfieri, Stefano Cavalieri, Federica Perrone, Laura D. Locati
Publikováno v:
Oncology. 97:112-118
Background: Recurrent or metastatic (R/M) skin squamous cell carcinoma (sSCC) not amenable of surgery or irradiation may benefit from systemic therapies. Epidermal growth factor receptor (EGFR) inhibitors and, more recently, immune checkpoint blocker
Autor:
Jeffrey M Weinberger, Gilad W. Vainer, Nir Hirshoren, Yakov Fellig, Issa Al-Kharouf, Ariela Knaanie, Tzahi Neuman, Aron Popovtzer, Ron Eliashar, Karen Meir, Alexander Maly
Publikováno v:
Oncology
Introduction: Immune-checkpoint inhibitors have demonstrated a significant survival benefit in metastatic and non-resectable head and neck squamous cell carcinoma (HNSCC). Patients with a combined positivity score (CPS) of 20 and higher benefit the m
Publikováno v:
Oncology. 98(12)
Background: Circulating tumor cells (CTCs) have been identified and shown to have prognostic and predictive roles in several types of carcinoma. More recently, aneuploid CTCs have become subject of a growing interest, as aneuploidy is considered a ha
Autor:
Noriyasu Kawai, Ryosuke Ando, Takahiro Yasui, Yoshihisa Mimura, Keitaro Iida, Toshiki Etani, Tomoki Okada, Taku Naiki, Nobuhiko Shimizu, Takashi Nagai, Yoshihiko Tasaki, Hiroki Kubota, Shuzo Hamamoto, Rika Banno, Yusuke Noda, Yosuke Sugiyama
Publikováno v:
Oncology. 98(12)
Background: We evaluated the prognostic efficacy of the Geriatric Nutritional Risk Index (GNRI) in second-line pembrolizumab (PEM) therapy for patients with metastatic urothelial carcinoma (mUC). Patients and Methods: From January 2018 to October 201
Autor:
Bernhard Doleschal, Clemens Venhoda, Regina Prommer, Andreas L. Petzer, Holger Rumpold, Helwig Valentin Wundsam, Clemens A. Schmitt, Sigrid Metz-Gercek
Publikováno v:
Oncology. 98(10)
Background: Adenocarcinoma of the esophagogastric junction (AEG) is a rare but rising tumor entity in the Western world. Treatment is complex, as multimodality is key to optimal results. However, trials solely including AEG are rare, and the question
Autor:
Kazuto Harada, Jeffrey H. Lee, Mariela A. Blum Murphy, Manoop S. Bhutani, Irene Thomas, Dilsa Mizrak Kaya, Graciela M. Nogueras González, Jane E. Rogers, Brian Weston, Jaffer A. Ajani, Prajnan Das, Brian D. Badgwell
Publikováno v:
Oncology. 98(8)
Background: Preoperative induction chemotherapy followed by chemoradiation yields better R0 resection rates, pathologic complete response (pCR) rates and improved survival for localized gastric adenocarcinoma (GAC). We report the effect of three-drug
Publikováno v:
Oncology. 94(4):233-242
Objective: The aim of this study was to characterize the expression of hydroxysteroid (17β) dehydrogenase type 12 (HSD17B12), an enzyme involved in the synthesis of arachidonic acid (AA), in ovarian cancer, and to study its coexpression with its ups
Autor:
Masashi Takano, Kento Kato, Hiroki Ishibashi, Junko Hirata, Tadashi Aoyama, Hideki Iwahashi, Morikazu Miyamoto, Hitoshi Tsuda, Hiroaki Soyama, Hiroko Matuura, Tomoyuki Yoshikawa, Ayako Suzuki, Kenichi Furuya
Publikováno v:
Oncology. 93:29-35
Objective: Most of the endometrial carcinomas are detected in early stages and have a better prognosis; however, predictive factors for recurrence have not been determined. Methods: Patients with grade 1 endometrioid carcinoma (EG1) according to the