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Autor:
Johannes P. M. Langedijk, Renske Bolder, Eirikur Saeland, Jan Serroyen, Roland Zahn, Hanneke Schuitemaker, Marjolein Heemskerk-van der Meer, Yolinda van Polanen, Joke Drijver, Leslie van der Fits
Publikováno v:
npj Vaccines, Vol 5, Iss 1, Pp 1-9 (2020)
NPJ Vaccines
NPJ Vaccines
While RSV is a major cause of respiratory morbidity in infants, vaccine development is hindered by the immaturity and Th2-bias of the infant immune system and the legacy of enhanced respiratory disease (ERD) after RSV infection following immunization
Autor:
Celia C. LaBranche, Benjamin Mildenberg, Sampa Santra, Andrea Cara, Barton F. Haynes, Erich J Baker, Donatella R.M. Negri, Maria Blasi, Mary E. Klotman, M. Anthony Moody, Wes Rountree, Kevin O. Saunders, Elizabeth C Wescott
Publikováno v:
npj Vaccines, Vol 5, Iss 1, Pp 1-9 (2020)
npj Vaccines
NPJ Vaccines
npj Vaccines
NPJ Vaccines
Despite incredible scientific efforts, there is no cure for HIV infection. While antiretroviral treatment (ART) can help control the virus and prevent transmission, it cannot eradicate HIV from viral reservoirs established before the initiation of th
Autor:
Kevin Tierney, David Safronetz, Geoff Soule, Bryce M. Warner, Kathy L. Frost, Stephanie A. Booth, Derek R. Stein
Publikováno v:
npj Vaccines, Vol 4, Iss 1, Pp 1-7 (2019)
NPJ Vaccines
NPJ Vaccines
The World Health Organization has identified Lassa virus (LASV) as one of the top five pathogens to cause a severe outbreak in the near future. This study assesses the ability of a leading vaccine candidate, recombinant Vesicular stomatitis virus exp