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Autor:
Johannes P. M. Langedijk, Renske Bolder, Eirikur Saeland, Jan Serroyen, Roland Zahn, Hanneke Schuitemaker, Marjolein Heemskerk-van der Meer, Yolinda van Polanen, Joke Drijver, Leslie van der Fits
Publikováno v:
npj Vaccines, Vol 5, Iss 1, Pp 1-9 (2020)
NPJ Vaccines
NPJ Vaccines
While RSV is a major cause of respiratory morbidity in infants, vaccine development is hindered by the immaturity and Th2-bias of the infant immune system and the legacy of enhanced respiratory disease (ERD) after RSV infection following immunization
Autor:
Kathleen A. Ross, Adel M. Talaat, Balaji Narasimhan, Yashdeep Phanse, Howard Steinberg, Chungyi Hansen, Akanksha Thukral
Publikováno v:
npj Vaccines, Vol 5, Iss 1, Pp 1-10 (2020)
NPJ Vaccines
NPJ Vaccines
Mycobacterium avium subsp. paratuberculosis (M. paratuberculosis) causes Johne’s disease in ruminants and is characterized by chronic gastroenteritis leading to heavy economic losses to the dairy industry worldwide. The currently available vaccine
Autor:
Charles A. Scanga, Mario Roederer, JoAnne L. Flynn, Mark Rodgers, Pauline Maiello, Joshua A Hackney, Thomas Lindenstrøm, Amy J. Myers, Victor Prikhodko, Dominick Laddy, Hannah P. Gideon, Patricia A. Darrah, Philana Ling Lin, Robert M. DiFazio, Peter Andersen, Thomas J. Evans, Robert A. Seder
Publikováno v:
npj Vaccines, Vol 4, Iss 1, Pp 1-13 (2019)
NPJ Vaccines
NPJ Vaccines
Tuberculosis (TB) is the leading cause of death from infection worldwide. The only approved vaccine, BCG, has variable protective efficacy against pulmonary TB, the transmissible form of the disease. Therefore, improving this efficacy is an urgent pr