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Publikováno v:
npj Vaccines, Vol 5, Iss 1, Pp 1-11 (2020)
NPJ Vaccines
NPJ Vaccines
A major challenge in dengue vaccine development is the need to induce immunity against four dengue (DENV) serotypes. Dengvaxia®, the only licensed dengue vaccine, consists of four variant dengue antigens, one for each serotype. Three doses of immuni
Autor:
Celia C. LaBranche, Benjamin Mildenberg, Sampa Santra, Andrea Cara, Barton F. Haynes, Erich J Baker, Donatella R.M. Negri, Maria Blasi, Mary E. Klotman, M. Anthony Moody, Wes Rountree, Kevin O. Saunders, Elizabeth C Wescott
Publikováno v:
npj Vaccines, Vol 5, Iss 1, Pp 1-9 (2020)
npj Vaccines
NPJ Vaccines
npj Vaccines
NPJ Vaccines
Despite incredible scientific efforts, there is no cure for HIV infection. While antiretroviral treatment (ART) can help control the virus and prevent transmission, it cannot eradicate HIV from viral reservoirs established before the initiation of th
Publikováno v:
npj Vaccines, Vol 4, Iss 1, Pp 1-8 (2019)
NPJ Vaccines
NPJ Vaccines
Nanoparticle-based delivery systems are being used to simplify and accelerate new vaccine development. Previously, we described the solid-phase synthesis of a 61-amino acid conjugate vaccine carrier comprising a α-helical domain followed by two univ