Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Yue Shen"'
Publikováno v:
Nature Communications. 13
With the completion of Sc2.0 chromosomes, synthetic chromosome rearrangement and modification by loxP-mediated evolution (SCRaMbLE) becomes more critical for in-depth investigation of fundamental biological questions and screening of industrially val
Autor:
Xiaoming Feng, Bing Wang, Zhina Sun, Wei Guo, He Ren, Kui Dong, Guogang Xu, Zhongchao Han, Qibing Leng, Huifang Huang, Dongming Zhou, Yuechen Luo, Gang Yu, Yue Shen, Lijun Fang, Wenwen Li, Yushan Zhou, Song Chen, Chunxiao Zhao, Jingru Liu, Zhonglong Li
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications
Nature Communications
To balance immunity and tolerance, the endogenous pool of Foxp3+ regulatory T (Treg) cells is tightly controlled, but the underlying mechanisms of this control remain poorly understood. Here we show that the number of Treg cells is negatively regulat
Autor:
Zengyi Ma, Cheng Peng, Yongfei Wang, Liangfu Zhou, Yao Zhao, Hongying Ye, Hong Chen, Zhijian Song, Chaowei Fu, Jianhua Chen, Yiming Li, Hong Peng, Cheng Luo, Feng Tang, Dan Zhao, Jiawei Shen, Shiqi Li, Aamir Fahira, Ying Mao, Zhiqiang Li, Wang Ye, Ming Shen, Chuanxin Huang, Xuefei Shou, Daming Gao, Siyu Deng, Zhifeng Shi, Min Chen, Chunjui Chen, Juan Zhou, Yongyong Shi, Qilin Zhang, Zhao Ye, Hai Yan, Yichao Zhang, Xuemin Jian, Lu Xie, Zhenwei Yao, Yue Shen, Zhaoyun Zhang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Nature Communications
Nature Communications
Cushing’s disease results from corticotroph adenomas of the pituitary that hypersecrete adrenocorticotropin (ACTH), leading to excess glucocorticoid and hypercortisolism. Mutations of the deubiquitinase gene USP8 occur in 35–62% of corticotroph a
Autor:
Yue Shen, Junbiao Dai, Lihui Wang, Yakun Guo, Qingyu Wu, Yizhi Cai, Chong Zhang, Weimin Zhang, Zhouqing Luo, Yun Wang, Linghuo Jiang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Luo, Z, Wang, L, Wang, Y, Zhang, W, Guo, Y, Shen, Y, Jiang, L, Wu, Q, Zhang, C, Cai, Y & Dai, J 2018, ' Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES ', Nature Communications, vol. 9, no. 1, 1930 . https://doi.org/10.1038/s41467-017-00806-y
Nature Communications
Luo, Z, Wang, L, Wang, Y, Zhang, W, Guo, Y, Shen, Y, Jiang, L, Wu, Q, Zhang, C, Cai, Y & Dai, J 2018, ' Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES ', Nature Communications, vol. 9, no. 1, 1930 . https://doi.org/10.1038/s41467-017-00806-y
Nature Communications
SCRaMbLE is a novel system implemented in the synthetic yeast genome, enabling massive chromosome rearrangements to produce strains with a large genotypic diversity upon induction. Here we describe a reporter of SCRaMbLEd cells using efficient select