Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ye Zheng"'
Autor:
Saiyu, Hang, Donggi, Paik, Lina, Yao, Eunha, Kim, Jamma, Trinath, Jingping, Lu, Soyoung, Ha, Brandon N, Nelson, Samantha P, Kelly, Lin, Wu, Ye, Zheng, Randy S, Longman, Fraydoon, Rastinejad, A Sloan, Devlin, Michael R, Krout, Michael A, Fischbach, Dan R, Littman, Jun R, Huh
Publikováno v:
Nature
Bile acids are abundant in the mammalian gut where they undergo bacteria-mediated transformation, generating a large pool of bioactive molecules. Although bile acids are known to affect host metabolism, cancer progression and innate immunity, it is u
Autor:
Saiyu, Hang, Donggi, Paik, Lina, Yao, Eunha, Kim, Jamma, Trinath, Jingping, Lu, Soyoung, Ha, Brandon N, Nelson, Samantha P, Kelly, Lin, Wu, Ye, Zheng, Randy S, Longman, Fraydoon, Rastinejad, A Sloan, Devlin, Michael R, Krout, Michael A, Fischbach, Dan R, Littman, Jun R, Huh
Publikováno v:
Nature. 576(7785)
Bile acids are abundant in the mammalian gut, where they undergo bacteria-mediated transformation to generate a large pool of bioactive molecules. Although bile acids are known to affect host metabolism, cancer progression and innate immunity, it is
Autor:
Mathias Leblanc, Christopher Liddle, Ronald M. Evans, Annette R. Atkins, Ruth T. Yu, Jae Myoung Suh, Yuqiong Liang, Ye Zheng, Michael Downes, Sihao Liu, Carmen Zhou, Sungsoon Fang, Yang Zhang, Albert Cheng, Sagar P. Bapat
Publikováno v:
Nature. 528:137-141
Age-associated insulin resistance (IR) and obesity-associated IR are two physiologically distinct forms of adult-onset diabetes. While macrophage-driven inflammation is a core driver of obesity-associated IR, the underlying mechanisms of the obesity-
Autor:
Randy S. Longman, Michael A. Fischbach, A. Sloan Devlin, Michael R. Krout, Lin Wu, Jun R. Huh, Soyoung Ha, Dan R. Littman, Saiyu Hang, Ye Zheng, Lina Yao, Eunha Kim, Samantha P. Kelly, Brandon N. Nelson, Jingping Lu, Fraydoon Rastinejad, Jamma Trinath, Donggi Paik
Publikováno v:
Nature. 579:E7-E7
Autor:
Takatoshi Chinen, Alexander Y. Rudensky, Rachel E. Niec, Dale T. Umetsu, Ye Zheng, Piper M. Treuting, Steven Z. Josefowicz, Hye Young Kim
Publikováno v:
Nature. 482:395-399
A balance between pro- and anti-inflammatory mechanisms at mucosal interfaces, which are sites of constitutive exposure to microbes and non-microbial foreign substances, allows for efficient protection against pathogens yet prevents adverse inflammat
Autor:
Alexander Y. Rudensky, Katherine A. Forbush, Ye Zheng, Steven Z. Josefowicz, Xiao P. Peng, Ashutosh Chaudhry
Publikováno v:
Nature. 463:808-812
Immune homeostasis is dependent on tight control over the size of a population of regulatory T (T(reg)) cells capable of suppressing over-exuberant immune responses. The T(reg) cell subset is comprised of cells that commit to the T(reg) lineage by up
Autor:
Marc A. Gavin, Steven Z. Josefowicz, Alexander Y. Rudensky, Arnold Kas, Tin-Tin Chu, Ye Zheng
Publikováno v:
Nature. 445:936-940
Transcription factor Foxp3 (forkhead box P3), restricted in its expression to a specialized regulatory CD4+ T-cell subset (T(R)) with a dedicated suppressor function, controls T(R) lineage development. In humans and mice, Foxp3 deficiency results in
Autor:
Arnold Kas, Lynn M. Corcoran, Jeong M. Kim, Paul deRoos, Piper M. Treuting, Ulf Klein, Alexander Y. Rudensky, Ye Zheng, Ashutosh Chaudhry, Tin-Tin Chu
Publikováno v:
Nature. 458(7236)
In the course of infection or autoimmunity, particular transcription factors orchestrate the differentiation of T(H)1, T(H)2 or T(H)17 effector cells, the responses of which are limited by a distinct lineage of suppressive regulatory T cells (T(reg))