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Autor:
Ruud van Winkel, Eugenia Kravariti, Matthias Weisbrod, Jim van Os, Bart P. F. Rutten, Lieuwe de Haan, Vaughan Bell, Behrooz Z. Alizadeh, Katja Schulze, Benedicto Crespo-Facorro, Claudia J. P. Simons, Jurjen J. Luykx, Assen Jablensky, Wiepke Cahn, Conrad Iyegbe, Frederike Schirmbeck, Elvira Bramon, John Powell, Jasmine Harju-Seppänen, Jeremy Hall, Rebecca M. Jones, René S. Kahn, Robin M. Murray, Luba Kalaydjieva, Dan Rujescu, Sonja M C de Zwarte, Marco Picchioni, Johan H. Thygesen, Roel A. Ophoff, Anjali Bhat, Therese van Amelsvoort, Timothea Toulopoulou, Siri Ranlund, Rebecca Muir, Kuang Lin, Diana Prata, Mei-Hua Hall, Ignacio Mata, Muriel Walshe, Stephen M. Lawrie, Karoline Kuchenbaecker, Madiha Shaikh, Eirini Zartaloudi, Isabelle Austin-Zimmerman, Evangelos Vassos, Richard Bruggeman, Agna A. Bartels-Velthuis, Andrew M. McIntosh, Haritz Irizar, Neeltje E.M. van Haren, Marta Di Forti, Andrew McQuillin, Alvaro Diez-Revuelta, Cathryn M. Lewis, Amelia Presman, Stella Calafato, Colm McDonald
Publikováno v:
Molecular Psychiatry, 26(9). Nature Publishing Group
Molecular psychiatry, 26(9), 5307-5319. Nature Publishing Group
Molecular Psychiatry, 26(9), 5307-5319. Nature Publishing Group
Molecular Psychiatry
Molecular Psychiatry, vol 26, iss 9
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Thygesen, J H, Presman, A, Harju-seppänen, J, Irizar, H, Jones, R, Kuchenbaecker, K, Lin, K, Alizadeh, B Z, Austin-zimmerman, I, Bartels-velthuis, A, Bhat, A, Bruggeman, R, Cahn, W, Calafato, S, Crespo-facorro, B, De Haan, L, De Zwarte, S M C, Di Forti, M, Díez-revuelta, Á, Hall, J, Hall, M, Iyegbe, C, Jablensky, A, Kahn, R, Kalaydjieva, L, Kravariti, E, Lawrie, S, Luykx, J J, Mata, I, Mcdonald, C, Mcintosh, A M, Mcquillin, A, Muir, R, Ophoff, R, Picchioni, M, Prata, D P, Ranlund, S, Rujescu, D, Rutten, B P F, Schulze, K, Shaikh, M, Schirmbeck, F, Simons, C J P, Toulopoulou, T, Van Amelsvoort, T, Van Haren, N, Van Os, J, Van Winkel, R, Vassos, E, Walshe, M, Weisbrod, M, Zartaloudi, E, Bell, V, Powell, J, Lewis, C M, Murray, R M & Bramon, E 2020, ' Genetic copy number variants, cognition and psychosis: a meta-analysis and a family study ', Molecular Psychiatry . https://doi.org/10.1038/s41380-020-0820-7
Molecular psychiatry, 26(9), 5307-5319. Nature Publishing Group
Molecular Psychiatry, 26(9), 5307-5319. Nature Publishing Group
Molecular Psychiatry
Molecular Psychiatry, vol 26, iss 9
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Thygesen, J H, Presman, A, Harju-seppänen, J, Irizar, H, Jones, R, Kuchenbaecker, K, Lin, K, Alizadeh, B Z, Austin-zimmerman, I, Bartels-velthuis, A, Bhat, A, Bruggeman, R, Cahn, W, Calafato, S, Crespo-facorro, B, De Haan, L, De Zwarte, S M C, Di Forti, M, Díez-revuelta, Á, Hall, J, Hall, M, Iyegbe, C, Jablensky, A, Kahn, R, Kalaydjieva, L, Kravariti, E, Lawrie, S, Luykx, J J, Mata, I, Mcdonald, C, Mcintosh, A M, Mcquillin, A, Muir, R, Ophoff, R, Picchioni, M, Prata, D P, Ranlund, S, Rujescu, D, Rutten, B P F, Schulze, K, Shaikh, M, Schirmbeck, F, Simons, C J P, Toulopoulou, T, Van Amelsvoort, T, Van Haren, N, Van Os, J, Van Winkel, R, Vassos, E, Walshe, M, Weisbrod, M, Zartaloudi, E, Bell, V, Powell, J, Lewis, C M, Murray, R M & Bramon, E 2020, ' Genetic copy number variants, cognition and psychosis: a meta-analysis and a family study ', Molecular Psychiatry . https://doi.org/10.1038/s41380-020-0820-7
The burden of large and rare copy number genetic variants (CNVs) as well as certain specific CNVs increase the risk of developing schizophrenia. Several cognitive measures are purported schizophrenia endophenotypes and may represent an intermediate p
Autor:
Velthorst E., Mollon J., Murray R. M., de Haan L., Germeys I. M., Glahn D. C., Arango C., van der Ven E., Di Forti M., Bernardo M., Guloksuz S., Delespaul P., Mezquida G., Amoretti S., Bobes J., Saiz P. A., Garcia-Portilla M. P., Santos J. L., Jimenez-Lopez E., Sanjuan J., Aguilar E. J., Arrojo M., Carracedo A., Lopez G., Gonzalez-Penas J., Parellada M., Atbasoglu C., Saka M. C., Ucok A., Alptekin K., Akdede B., Binbay T., Altinyazar V., Ulas H., Yalincetin B., Gumus-Akay G., Beyaz B. C., Soygur H., Cankurtaran E. S., Kaymak S. U., Maric N. P., Mihaljevic M. M., Petrovic S. A., Mirjanic T., Del-Ben C. M., Ferraro L., Gayer-Anderson C., Jones P. B., Jongsma H. E., Kirkbride J. B., La Cascia C., Lasalvia A., Tosato S., Llorca P. -M., Menezes P. R., Morgan C., Quattrone D., Menchetti M., Selten J. -P., Szoke A., Tarricone I., Tortelli A., McGuire P., Valmaggia L., Kempton M. J., van der Gaag M., Riecher-Rossler A., Bressan R. A., Barrantes-Vidal N., Nelson B., McGorry P., Pantelis C., Krebs M. -O., Ruhrmann S., Sachs G., Rutten B. P. F., van Os J., Alizadeh B. Z., van Amelsvoort T., Bartels-Velthuis A. A., Bruggeman R., van Beveren N. J., Luykx J. J., Cahn W., Simons C. J. P., Kahn R. S., Schirmbeck F., van Winkel R., Calem M., Tognin S., Modinos G., Pisani S., Kraan T. C., van Dam D. S., Burger N., Amminger G. P., Politis A., Goodall J., Borgwardt S., Studerus E., Gadelha A., Brietzke E., Asevedo G., Asevedo E., Zugman A., Dominguez-Martinez T., Monsonet M., Cristobal-Narvaez P., Racioppi A., Kwapil T. R., Kazes M., Daban C., Bourgin J., Gay O., Mam-Lam-Fook C., Nordholm D., Rander L., Krakauer K., Glenthoj L. B., Glenthoj B., Gebhard D., Arnhold J., Klosterkotter J., Lasser I., Winklbaur B., Reichenberg A.
Publikováno v:
EU-GEI High Risk Study 2021, ' Cognitive functioning throughout adulthood and illness stages in individuals with psychotic disorders and their unaffected siblings ', Molecular Psychiatry, vol. 26, no. 8, pp. 4529-4543 . https://doi.org/10.1038/s41380-020-00969-z
Molecular Psychiatry, 26(8), 4529-4543. Nature Publishing Group
Scopus
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Molecular Psychiatry, 26, 4529-4543. Nature Publishing Group
Velthorst, E, Mollon, J, Murray, R M, de Haan, L, Germeys, I M, Glahn, D C, Arango, C, van der Ven, E, Di Forti, M, Bernardo, M, Guloksuz, S, Delespaul, P, Mezquida, G, Amoretti, S, Bobes, J, Saiz, P A, García-Portilla, M P, Santos, J L, Jiménez-López, E, Sanjuan, J, Aguilar, E J, Arrojo, M, Carracedo, A, López, G, González-Peñas, J, Parellada, M, Atbaşoğlu, C, Saka, M C, Üçok, A, Alptekin, K, Akdede, B, Binbay, T, Altınyazar, V, Ulaş, H, Yalınçetin, B, Gümüş-Akay, G, Beyaz, B C, Soygür, H, Cankurtaran, E Ş, Kaymak, S U, Maric, N P, Mihaljevic, M M, Petrovic, S A, Mirjanic, T, Del-Ben, C M, Ferraro, L, Gayer-Anderson, C, Jones, P B, Nordholm, D, Glenthøj, B & EU-GEI High Risk Study 2021, ' Cognitive functioning throughout adulthood and illness stages in individuals with psychotic disorders and their unaffected siblings ', Molecular Psychiatry, vol. 26, pp. 4529–4543 . https://doi.org/10.1038/s41380-020-00969-z
Molecular psychiatry, 26(8), 4529-4543. Nature Publishing Group
Molecular Psychiatry, 26(8), 4529-4543. Nature Publishing Group
Scopus
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Molecular Psychiatry, 26, 4529-4543. Nature Publishing Group
Velthorst, E, Mollon, J, Murray, R M, de Haan, L, Germeys, I M, Glahn, D C, Arango, C, van der Ven, E, Di Forti, M, Bernardo, M, Guloksuz, S, Delespaul, P, Mezquida, G, Amoretti, S, Bobes, J, Saiz, P A, García-Portilla, M P, Santos, J L, Jiménez-López, E, Sanjuan, J, Aguilar, E J, Arrojo, M, Carracedo, A, López, G, González-Peñas, J, Parellada, M, Atbaşoğlu, C, Saka, M C, Üçok, A, Alptekin, K, Akdede, B, Binbay, T, Altınyazar, V, Ulaş, H, Yalınçetin, B, Gümüş-Akay, G, Beyaz, B C, Soygür, H, Cankurtaran, E Ş, Kaymak, S U, Maric, N P, Mihaljevic, M M, Petrovic, S A, Mirjanic, T, Del-Ben, C M, Ferraro, L, Gayer-Anderson, C, Jones, P B, Nordholm, D, Glenthøj, B & EU-GEI High Risk Study 2021, ' Cognitive functioning throughout adulthood and illness stages in individuals with psychotic disorders and their unaffected siblings ', Molecular Psychiatry, vol. 26, pp. 4529–4543 . https://doi.org/10.1038/s41380-020-00969-z
Molecular psychiatry, 26(8), 4529-4543. Nature Publishing Group
The European Community’s Seventh Framework Programme under grant agreement No. HEALTH-F2-2010-241909 (EUGEI); The Spanish sample was supported by the Spanish Ministry of Science and Innovation, Instituto de Salud Carlos III (SAM16PE07CP1, PI16/0201
Publikováno v:
Molecular Psychiatry, 26(3), 897-906. Nature Publishing Group
The locus coeruleus (LC) supplies norepinephrine to the brain, is one of the first sites of tau deposition in Alzheimer's disease (AD) and modulates a variety of behaviors and cognitive functions. Transgenic mouse models showed that norepinephrine dy
Autor:
Tim S. Heistek, Sara Hijazi, Philip Scheltens, Derya R. Shimshek, August B. Smit, Ulf Neumann, Ronald E. van Kesteren, Huibert D. Mansvelder
Publikováno v:
Molecular Psychiatry, 25(12), 3380-3398. Nature Publishing Group
Molecular Psychiatry
Hijazi, S, Heistek, T S, Scheltens, P, Neumann, U, Shimshek, D R, Mansvelder, H D, Smit, A B & van Kesteren, R E 2020, ' Early restoration of parvalbumin interneuron activity prevents memory loss and network hyperexcitability in a mouse model of Alzheimer’s disease ', Molecular Psychiatry, vol. 25, no. 12, pp. 3380-3398 . https://doi.org/10.1038/s41380-019-0483-4
Molecular Psychiatry
Hijazi, S, Heistek, T S, Scheltens, P, Neumann, U, Shimshek, D R, Mansvelder, H D, Smit, A B & van Kesteren, R E 2020, ' Early restoration of parvalbumin interneuron activity prevents memory loss and network hyperexcitability in a mouse model of Alzheimer’s disease ', Molecular Psychiatry, vol. 25, no. 12, pp. 3380-3398 . https://doi.org/10.1038/s41380-019-0483-4
Neuronal network dysfunction is increasingly recognized as an early symptom in Alzheimer’s disease (AD) and may provide new entry points for diagnosis and intervention. Here, we show that amyloid-beta-induced hyperexcitability of hippocampal inhibi
Autor:
Tiffany M. Chaim-Avancini, Christopher R.K. Ching, Edith Pomarol-Clotet, Chantal Henry, Erick J. Canales-Rodríguez, Pedro G.P. Rosa, Jochen Bauer, Julian A Pineda-Zapata, Tobias Kaufmann, Josselin Houenou, Eduard Vieta, Axel Krug, Marcus V. Zanetti, Ana M. Díaz-Zuluaga, Dan J. Stein, Jose Manuel Goikolea, Benson Mwangi, Xavier Caseras, Carlos López-Jaramillo, Tomas Hajek, Nils Opel, Rhoshel K. Lenroot, Paul M. Thompson, Hugo G. Schnack, Bronwyn Overs, Martin Alda, Philip B. Mitchell, Colm McDonald, Ronny Redlich, Lars T. Westlye, Daniel Emden, Thomas Trappenberg, Leila Nabulsi, Erlend Bøen, Bruno Dietsche, Daniel H. Wolf, Fleur M. Howells, Theophilus N. Akudjedu, Edouard Duchesnay, Ingrid Agartz, Bernhard T. Baune, Abraham Nunes, Lisa T. Eyler, Mar Fatjó-Vilas, Torbjørn Elvsåshagen, Ulrik Fredrik Malt, Neda Jahanshad, Sonya Foley, Tim Hahn, Dag Alnæs, Ole A. Andreassen, Raymond Salvador, Geraldo F. Busatto, Joanne Kenney, Neeltje E.M. van Haren, Caterina del Mar Bonnín, David C. Glahn, Dilara Yüksel, Henk Temmingh, Tilo Kircher, Silvia Alonso-Lana, Udo Dannlowski, Dara M. Cannon, Pauline Favre, Jair C. Soares, Dominik Grotegerd, Gloria Roberts, Theodore D. Satterthwaite, Nhat Trung Doan, Derrek P. Hibar, Trine Vik Lagerberg, Anne Uhlmann, Rodrigo Machado-Vieira, Janice M. Fullerton
Publikováno v:
Molecular Psychiatry, 25(9), 2130-2143. Nature Publishing Group
Molecular Psychiatry
Repositorio UdeA
Universidad de Antioquia
instacron:Universidad de Antioquia
Molecular psychiatry, vol 25, iss 9
Dipòsit Digital de la UB
Universidad de Barcelona
Molecular Psychiatry
Repositorio UdeA
Universidad de Antioquia
instacron:Universidad de Antioquia
Molecular psychiatry, vol 25, iss 9
Dipòsit Digital de la UB
Universidad de Barcelona
Bipolar disorders (BDs) are among the leading causes of morbidity and disability. Objective biological markers, such as those based on brain imaging, could aid in clinical management of BD. Machine learning (ML) brings neuroimaging analyses to indivi
Publikováno v:
Molecular Psychiatry
Molecular Psychiatry. Nature Publishing Group
Molecular Psychiatry. Nature Publishing Group
Autor:
Terri Gelbart, D L Graham, G E Sandusky, Anantha Shekhar, J O Niezer, Daniel R. Salomon, A. Williams, Sunil M. Kurian, H L Dainton, A Ballew, Helen Le-Niculescu, T. Jones, E M Niculescu, K. Roseberry, V Venugopal, Daniel F. Levey, Nicholas J. Schork, M Yard, Alexander B. Niculescu, Peter Phalen
Publikováno v:
Molecular Psychiatry
Suicide remains a clear, present and increasing public health problem, despite being a potentially preventable tragedy. Its incidence is particularly high in people with overt or un(der)diagnosed psychiatric disorders. Objective and precise identific
Publikováno v:
Molecular Psychiatry
Chronic stress can be a precipitating factor in the onset of depression. Lentiviral-mediated knockdown of HCN1 protein expression and reduction of functional Ih produce antidepressant behavior. However, whether h-channels are altered in an animal mod
Autor:
L. Fernández de la Cruz, David Mataix-Cols, Catarina Almqvist, Gustaf Brander, Ralf Kuja-Halkola, Paul Lichtenstein, Eva Serlachius, Mina Rydell, Henrik Larsson, Christian Rück, Brian M. D’Onofrio
Publikováno v:
Molecular Psychiatry
Adverse perinatal events may increase the risk of Tourette’s and chronic tic disorders (TD/CTD), but previous studies have been unable to control for unmeasured environmental and genetic confounding. We aimed to prospectively investigate potential
Publikováno v:
Molecular Psychiatry
Neuropsychiatric disorders place an enormous medical burden on patients across all social and economic ranks. The current understanding of the molecular and cellular causes of neuropsychiatric disease remains limited, which leads to a lack of targete