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Autor:
Junyue Zhang, Zhenyu Ji, Yiqiang Yuan, Xiangguang Meng, Qian Wang, Keke Wang, Zhiying Li, Shuwei Ning, Dandan Fan, Lei Hua
Publikováno v:
Molecular Medicine Reports
Acute myocardial infarction can be caused by ischemia/reperfusion (I/R) injury; however, the mechanism underlying I/R is not completely understood. The present study investigated the functions and mechanisms underlying microRNA (miR)‑494 in I/R‑i
Publikováno v:
Molecular Medicine Reports
Eupatorium perfoliatum L. (E. perfoliatium) has been used traditionally for treating fever, malaria and inflammation-associated diseases. Eupafolin, the extract of E. perfoliatium, was also reported to suppress inflammation. The present study aimed t
Autor:
Xiaohong Xue, Pei Lu, Wenjing Diao, Yuankui Cao, Jun Li, Hua Feng, Caiying Zhu, Yu Song, Qisang Guo
Publikováno v:
Molecular Medicine Reports
Tripartite motif‑containing (TRIM) 14 is a protein of the TRIM family. Studies have indicated that TRIM14 may be used as an oncogene in tumor cells, such as osteosarcoma, non‑small cell lung cancer and breast cancer through different pathways. Ho
Publikováno v:
Molecular Medicine Reports
Apoptosis of nucleus pulposus (NP) cells has an important role in the process of intervertebral disc degeneration (IDD), and the search for novel compounds to prevent apoptosis from occurring is urgently required. In the present study, syringic acid
Publikováno v:
Molecular Medicine Reports
The discovery, introduction and clinical use of prognostic and diagnostic biomarkers has significantly improved outcomes for patients with various illnesses, including bladder cancer (BC) and other bladder-related diseases, such as benign bladder dys
Publikováno v:
Molecular Medicine Reports
Treatment of human estrogen receptor (ER)-positive breast cancer (ER+ BC) using conventional chemotherapy remains a challenge and is often ineffective as a result of tumor metastasis. The present study aimed to investigate the ability of narasin, an
Publikováno v:
Molecular Medicine Reports
The present study explored whether bone morphogenetic proteins (BMPs) and Wnt/β-catenin signaling pathways were involved in the 1,25(OH)2D3-induced inhibition of osteogenic differentiation in bone marrow-derived mesenchymal stem cells (BMSCs). To ev
Autor:
Jun Zhang, Qian Chen, Zhanhui Feng, Ya Chen, Xuejiao Zhou, Yan Peng, Haiqing Zhang, Junwei Zeng, Zucai Xu, Jing Wang, Hao Huang
Publikováno v:
Molecular Medicine Reports
Epilepsy is a chronic nervous system disease. Excessive increase of the excitatory neurotransmitter glutamate in the body results in an imbalance of neurotransmitters and excessive excitation of neurons, leading to epileptic seizures. Long-term recur
Publikováno v:
Molecular Medicine Reports
Mechanical ventilation (MV) can contribute to ventilator-induced lung injury (VILI); dexmedetomidine (Dex) treatment attenuates MV-related pulmonary inflammation, but the mechanisms remain unclear. Therefore, the present study aimed to explore the pr
Autor:
Lirong Xu, Xiaoli Xu, Zhixiao Lin, Nan Pang, Xueyong Li, Rong Huang, Xiaolin Wang, Xingxing Li, Jinqing Li
Publikováno v:
Molecular Medicine Reports
Wound healing is a complex physiological process in which fibrocytes serve a vital role. However, the mechanism underlying the recruitment of fibrocytes during wound healing remains largely unknown. The present study aimed to investigate whether endo