Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Prasad A"'
Autor:
D. Albert Joubert, Paul Monaghan, Prasad N. Paradkar, William J. McKinstry, Michelle Cummins, Gregory W. Moseley, Julio Rodriguez-Andres, Peter J. Walker
Publikováno v:
Journal of Virology
Wongabel virus (WONV) is an arthropod-borne rhabdovirus that infects birds. It is one of the growing array of rhabdoviruses with complex genomes that encode multiple accessory proteins of unknown function. In addition to the five canonical rhabdoviru
Autor:
Abhik Saha, Mahadesh Prasad Aj, Hem Chandra Jha, Erle S. Robertson, Qiliang Cai, Jie Lu, Santosh Kumar Upadhyay
Publikováno v:
Journal of Virology. 87:5255-5269
The DNA damage response (DDR) of host cells is utilized by a number of viruses to establish and propagate their genomes in the infected cells. We examined the expression of the DDR genes during Kaposi's sarcoma-associated herpesvirus (KSHV) infection
Autor:
Sonald Duclair, Vinayaka R. Prasad, Siddhartha A. K. Datta, Alan Rein, Dhivya Ramalingam, Andrew D. Ellington
Publikováno v:
Journal of Virology. 85:305-314
Gag orchestrates the assembly and release of human immunodeficiency virus type 1 (HIV-1) particles. We explored here the potential of anti-Gag RNA aptamers to inhibit HIV-1 replication. In vitro , RNA aptamers raised against an HIV-1 Gag protein, lac
Autor:
B. V. Venkataram Prasad, Kyoko Higo-Moriguchi, Koki Taniguchi, Philip R. Dormitzer, Zhen-Yu J. Sun, Nilah Monnier
Publikováno v:
Journal of Virology. 80:1513-1523
The most intensively studied rotavirus strains initially attach to cells when the “heads” of their protruding spikes bind cell surface sialic acid. Rotavirus strains that cause disease in humans do not bind this ligand. The structure of the siali
Publikováno v:
Journal of Virology. 77:5837-5845
Human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT), like all retroviral RTs, is a versatile DNA polymerase that can copy both RNA and DNA templates. In spite of extensive investigations into the structure-function of this enzyme,
Autor:
Shuvomoy Banerjee, Abhik Saha, Erle S. Robertson, Mahadesh Prasad Aj, Hem Chandra Jha, Jie Lu
Publikováno v:
Journal of virology. 88(7)
Epstein-Barr virus (EBV) latent antigen EBNA3C is implicated in B-cell immortalization and linked to several B-cell malignancies. Deregulation of H2AX can induce genomic instability with increased chromosomal aberrations, which ultimately leads to tu
Autor:
J. Denise Wetzel, Erik S. Barton, Terence S. Dermody, B. V. Venkataram Prasad, Sharmila K. Mukherjee, Emma L. Nason
Publikováno v:
Journal of Virology. 75:6625-6634
Reovirus virions are nonenveloped icosahedral particles consisting of two concentric protein shells, termed outer capsid and core. Outer-capsid protein ς1 is the viral attachment protein and binds carbohydrate molecules on the surface of host cells.
Publikováno v:
Journal of Virology. 75:1632-1642
In rotavirus, transcription of the 11 double-stranded RNA genome segments occurs within the structurally intact subviral particle, and nascent transcripts are released through channels penetrating the two capsid layers at the icosahedral vertices. To
Autor:
Sue E. Crawford, Joseph M. Hyser, Mary K. Estes, James R. Broughman, Liya Hu, Jeanette M. Criglar, B. V. Venkataram Prasad
Publikováno v:
Journal of virology. 88(2)
Rotavirus (RV) replication occurs in cytoplasmic inclusions called viroplasms whose formation requires the interactions of RV proteins NSP2 and NSP5; however, the specific role(s) of NSP2 in viroplasm assembly remains largely unknown. To study viropl
Publikováno v:
Journal of Virology. 74:10202-10206
If foreign genes are ubiquitously expressed in mice using a viral vector, expression is abrogated by CD8+cells in 2 to 4 weeks. However, if the expression of the genes is confined to skeletal muscle cells, the CD8+T-cell response is much weaker and e