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Autor:
Catherine Luedke, Jerald Z. Gong, Lian-He Yang, Yue Zhao, Rachel Jug, Jenna McCracken, Jonathan Galeotti, Jake Maule, Imran Siddiqi, Endi Wang, Chuanyi M. Lu
Publikováno v:
Journal of Clinical Pathology. 75:292-301
AimsMyeloid neoplasms occur in the setting of chronic lymphocytic leukaemia (CLL)/CLL-like disease. The underlying pathogenesis has not been elucidated.MethodsRetrospectively analysed 66 cases of myeloid neoplasms in patients with CLL/CLL-like diseas
Publikováno v:
Journal of Clinical Pathology. 75:285-287
Granulomatous mycosis fungoides (MF) poses multiple diagnostic challenges, which commonly delay diagnosis. The clinical morphology of the lesions mimic other granulomatous disorders. Biopsy findings of lymphocyte epidermotropism and an elevated CD4:C
Autor:
Terumichi Nakagawa, Masatoshi Wakui, Shusaku Oka, Mitsuru Murata, Yoshino Kondo, Yuko Ozaki, Hisako Katagiri, Yuta Fujimori, Shoko Nakamura
Publikováno v:
Journal of Clinical Pathology. 74:251-256
AimsWhile antithrombin (AT)-independent inhibitors targeting thrombin or activated factor X have been assessed through clot waveform (CWA), there are no reports on assessment with respect to AT-dependent anticoagulants. The present study aims to char
Autor:
Mathew Burgess, Stephen Jolles, Colin Price, Rachael Steven, Emily Carne, Kathyrn Bramhall, Frances McGuire, Sonali Wijetilleka, Mo Moody, Soha Zouwail, Daniel Farewell, Mark J. Ponsford, Tariq El-Shanawany, Tayyeb A. Tahir
Publikováno v:
Journal of Clinical Pathology
AimsAn association between antibody deficiency and clozapine use in individuals with schizophrenia has recently been reported. We hypothesised that if clozapine-associated hypogammaglobulinaemia was clinically relevant this would manifest in referral
Publikováno v:
Journal of Clinical Pathology. 73:126-138
Background‘Double-hit’ lymphoma (DHL) and ‘double-expression’ lymphoma (DEL) involving gene rearrangement and protein expression of MYC and BCL2/BCL6 have recently become the most commonly used terms to describe the poor prognostic types of d
Publikováno v:
Journal of Clinical Pathology. 73:7-13
AimsHereditary protein S (PS) deficiency is one of the natural anticoagulant deficiencies causing thrombophilia. We herein described a young male with recurrent deep venous thrombosis, who was diagnosed as type I PS deficiency with compound heterozyg
Autor:
Teresa Rampino, Gioacchino D'Ambrosio, Federica Borrelli de Andreis, Alessandro Vanoli, Laura Verga, Valentina Ravetta, Antonio Di Sabatino, Caterina Mengoli, Marco Paulli, Marco Vincenzo Lenti, Marilena Gregorini
Publikováno v:
Journal of Clinical Pathology
COVID-19, caused by SARS-CoV-2, has become a global threat in a matter of months. In particular, Italy has been one of the most affected areas worldwide. Data regarding the clinical picture and clinical course of COVID-19 are still lacking, especiall
Publikováno v:
Journal of Clinical Pathology
Basal cell carcinoma (BCC) is the most common human malignant neoplasm. However, there are multiple BCC subtypes that share clinical features while demanding different management. We present a case of a woman with hundreds of BCCs throughout her body
Autor:
Parveen Bahel, Richard Torres, Henry M. Rinder, Jocelyn B. Chandler, Alexa J. Siddon, Christopher A. Tormey
Publikováno v:
Journal of Clinical Pathology. 72:177-180
Most fibrinogen replacement strategies focus on quantitative deficiencies. A thrombin time (TT) mixing study helped to assess qualitative defects caused by dysfibrinogens. Plasma samples were collected from non-anticoagulated subjects (n=6) meeting l
Autor:
Dipti M. Karamchandani, Runjan Chetty
Publikováno v:
Journal of Clinical Pathology. 71:665-671
Immune checkpoint inhibitors (CPIs) are a relatively new class of ‘miracle’ dugs that have revolutionised the treatment and prognosis of some advanced-stage malignancies, and have increased the survival rates significantly. This class of drugs in