Zobrazeno 101 - 110
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Autor:
Aarnoud Huissoon, Paul Dhillon, Sheryl Gorrie, Mamidipudi Thirumala Krishna, Sadia Noorani, Oliver Chapman, Alex G. Richter, Fayza Al-Ghanmi, Lavanya Diwakar
Publikováno v:
Journal of Clinical Pathology. 63:275-277
Rituximab, an anti-CD20 chimeric antibody, is the first monoclonal agent to be used in the therapy of cancer. It has been hailed as one of the most important therapeutic developments of the decade. While transient peripheral B cell depletion is commo
Autor:
S J Machin, S L Allford
Publikováno v:
Journal of Clinical Pathology. 53:497-501
Thrombotic thrombocytopenic purpura (TTP) was first described by Moschowitz in 1924.1 Although it is now well recognised, being characterised by the classic pentad of fever, thrombocytopenia, microangiopathic haemolytic anaemia (MAHA), renal impairme
Publikováno v:
Journal of Clinical Pathology. 53:561-564
A 58 year old male heavy smoker presented with intracranial haemorrhage and erythrocytosis. Four aetiologies of polycythaemia—polycythaemia rubra vera (PRV), renal cell carcinoma, sleep apnoea syndrome, and relative polycythaemia—were found to be
Publikováno v:
Journal of Clinical Pathology. 53:470-475
Aims —To determine the conditions of photodynamic inactivation of vesicular stomatitis virus (VSV) added to pooled coumarin plasma and the effects of the photodynamic treatment on the prothrombin times and international normalised ratio (INR) in a
Autor:
A R W Forrest, C M Milroy
Publikováno v:
Journal of Clinical Pathology. 53:277-281
Aims —To perform a toxicological analysis of deaths involving methadone and to determine the fatal concentration of methadone in such deaths. Methods— Deaths in which methadone was mentioned in the cause of death were identified. Deaths were divi
Autor:
Francisco F. Nogales, Ovidiu Preda, E Goez, K Balachandran, Andrada Loghin, Simona Stolnicu, M A Aleykutty
Publikováno v:
Journal of Clinical Pathology. 62:942-944
Müllerian adenosarcomas are tumours of low malignant potential with proliferation of benign glands and low grade endometrial stromal sarcoma (LGESS). Unusually, the latter may include foci of uterine tumours resembling ovarian sex-cord tumours (UTRO
Publikováno v:
Journal of Clinical Pathology. 62:862-864
A patient presented with breathlessness, weight loss and nocturnal sweating. Investigations revealed mild airway obstruction. Bronchoscopy was normal but CT scan demonstrated pleural thickening and a small area of shadowing within the right lung (fig
Publikováno v:
Journal of Clinical Pathology. 62:951-953
The loss of fluid and electrolytes from a high-output ileostomy (>1200 ml/day) can quickly result in dehydration and if not properly managed may cause acute renal failure. The management of a high-output ileostomy is based upon three principles: corr
Autor:
Keith Gelly, D Brass, Sudhir Tauro, Mark Sales, Michael J. Groves, Stephanie F. MacCallum, Joan Cunningham
Publikováno v:
Journal of Clinical Pathology. 62:468-470
Autoimmune haemolysis or thrombocytopenia can complicate purine nucleoside monotherapy for chronic lymphocytic leukaemia (CLL), but Evans syndrome is rare. This is a report of the occurrence of pancytopenia secondary to a unique combination of red ce
Publikováno v:
Journal of Clinical Pathology. 62:474-476
Background:Recent data have shown a fall in vascular endothelial growth factor (VEGF) concentrations after bisphosphonate (BP) treatment in BP-naïve patients. It has therefore been proposed that BPs may have in vivo anti-VEGF effects.Aims:To explore