Zobrazeno 1 - 10
of 17 516
pro vyhledávání: ''
Autor:
Yi-Shyun Lai, Cheng-Chi Chang, Yong-Yi Chen, Thi My Hang Nguyen, Jixuan Xu, Ying-Chi Chen, Yu-Fen Chang, Chia-Yih Wang, Pai-Sheng Chen, Shih-Chieh Lin, I-Chen Peng, Shaw-Jenq Tsai, Wen-Tai Chiu
Publikováno v:
Journal of Cell Science.
Mitochondrial dynamics regulate the quality and morphology of mitochondria. Calcium (Ca2+) plays an important role in regulating mitochondrial function. Here, we investigated the effects of optogenetically engineered Ca2+ signaling on mitochondrial d
Autor:
Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick Caswell
Publikováno v:
Journal of Cell Science.
Endocytic recycling controls the return of internalised cargos to the plasma membrane to coordinate their positioning, availability and downstream signalling. The Rab4 and Rab11 small GTPase families regulate distinct recycling routes, broadly classi
Publikováno v:
Journal of Cell Science.
The budding yeast Saccharomyces cerevisiae has a closed mitosis in which the mitotic spindle and cytoplasmic microtubules (MTs) used to segregate chromosomes remain separated by the nuclear envelope throughout the cell cycle. Kar3, the yeast kinesin-
Autor:
Chandra Ramakrishnan, Cécile Fort, Sara Rute Marques, David J. P. Ferguson, Marion Gransagne, Jake Baum, Soraya Chaouch, Elisabeth Mouray, Linda Kohl, Richard J. Wheeler, Robert E. Sinden
Publikováno v:
Journal of Cell Science.
Flagella are important for eukaryote cell motility, including in sperm, and are vital for life cycle progression of many unicellular eukaryotic pathogens. The “9+2” axoneme in most motile flagella comprises nine outer doublet and two central-pair
Publikováno v:
Journal of Cell Science.
Mitotic fidelity is crucial for the faithful distribution of genetic information into the daughter cells. Many fungal species, including the fission yeast Schizosaccharomyces pombe, undergo a closed form of mitosis, during which the nuclear envelope
Autor:
Amruta Vasudevan, Reshma Maiya, Keertana Venkatesh, Vinod Kumar, Parul Sood, Kausalya Murthy, Sandhya P. Koushika, Gautam I. Menon
Publikováno v:
Journal of Cell Science.
Stationary clusters of vesicles are a prominent feature of axonal transport, but little is known about their physiological and functional relevance to axonal transport. We investigate the role of vesicle motility characteristics in modulating the for
Publikováno v:
Journal of Cell Science. 137
Paracingulin (CGNL1) is recruited to tight junctions (TJs) by ZO-1 and to adherens junctions (AJs) by PLEKHA7. PLEKHA7 has been reported to bind to the microtubule minus-end-binding protein CAMSAP3, to tether microtubules to the AJs. Here, we show th
Autor:
Siavash Khosravi, Xenia Chelius, Ann-Katrin Unger, Daniela Rieger, Johanna Frickel, Timo Sachsenheimer, Christian Lüchtenborg, Rico Schieweck, Britta Brügger, Benedikt Westermann, Till Klecker, Walter Neupert, Max E. Harner
Publikováno v:
Journal of Cell Science. 136
Mitochondria are essential organelles of eukaryotic cells and are characterized by their unique and complex membrane system. They are confined from the cytosol by an envelope consisting of two membranes. Signals, metabolites, proteins and lipids have
Publikováno v:
Journal of Cell Science. 136
Cells keep their proteome functional by the action of the proteostasis network, composed of the chaperones, the ubiquitin-proteasome system and autophagy. The decline of this network results in the accumulation of protein aggregates and is associated
Autor:
Motoaki Hiraoka, Yuki Kiyota, Shinnosuke Kawai, Yusuke Notsu, Kohei Yamada, Katsuyuki Kurashima, Jing-Wen Chang, Shunsuke Shimazaki, Ayumu Yamamoto
Publikováno v:
Journal of Cell Science. 136
Upon exhaustion of essential environmental nutrients, unicellular organisms cease cell division and enter stationary phase, a metabolically repressed state essential for cell survival in stressful environments. In the fission yeast Schizosaccharomyce