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Autor:
Wei Guo, Jianguo Zhang, Yi Li, Guilin Huang, Moyi Sun, Longjiang Li, Kai Yang, Wei Ran, Xiuqin Li, Zhangui Tang
Publikováno v:
International Journal of Oral Science, Vol 13, Iss 1, Pp 1-6 (2021)
International Journal of Oral Science
International Journal of Oral Science
The first gene therapy product, recombinant adenovirus human p53 (rAd-p53), has been approved by CFDA since 2013. During these years, most of the clinical trials and the relevant basic research were carried out by Chinese oncologists. Gendicine was p
Autor:
Yifang Liu, Jiaojiao Yang, Li Luo, Wei Wu, Kaijing Zhong, Jiyao Li, Mingyue Han, Lizhong Sun, Shijie Shi, Libang He
Publikováno v:
International Journal of Oral Science, Vol 13, Iss 1, Pp 1-14 (2021)
International Journal of Oral Science
International Journal of Oral Science
Unrestrained inflammation is harmful to tissue repair and regeneration. Immune cell membrane-camouflaged nanoparticles have been proven to show promise as inflammation targets and multitargeted inflammation controls in the treatment of severe inflamm
Publikováno v:
International Journal of Oral Science, Vol 13, Iss 1, Pp 1-11 (2021)
International Journal of Oral Science
International Journal of Oral Science
Head and neck squamous cell carcinoma (HNSCC), an aggressive malignancy, is characterized by high morbidity and low survival rates with limited therapeutic options outside of regional surgery, conventional cytotoxic chemotherapy, and irradiation. Inc
Publikováno v:
International Journal of Oral Science, Vol 13, Iss 1, Pp 1-10 (2021)
International Journal of Oral Science
International Journal of Oral Science
External cervical resorption (ECR) refers to a pathological state in which resorption tissues penetrate into the dentin at the cervical aspect of the root. Despite being latent in its initial phase, ECR could cause severe damage to mineralized dental
Autor:
Jinglun Zhang, Yufeng Zhang, Hudi Xu, Guixin Zhu, Qin Zhao, Zifan Zhao, Yan Wei, Haibin Xia, Chengcheng Yin, Xiaoxin Zhang, Jinyang Wang
Publikováno v:
International Journal of Oral Science, Vol 13, Iss 1, Pp 1-8 (2021)
International Journal of Oral Science
International Journal of Oral Science
Mineralized tissue regeneration is an important and challenging part of the field of tissue engineering and regeneration. At present, autograft harvest procedures may cause secondary trauma to patients, while bone scaffold materials lack osteogenic a
Publikováno v:
International Journal of Oral Science, Vol 13, Iss 1, Pp 1-10 (2021)
International Journal of Oral Science
International Journal of Oral Science
Hyperglycemia induces chronic low-grade inflammation (inflammaging), which is a newly identified contributor to diabetes-related tissue lesions, including the inflammatory bone loss in periodontitis. It is also a secondary senescent pattern mediated
Publikováno v:
International Journal of Oral Science, Vol 12, Iss 1, Pp 1-9 (2020)
International Journal of Oral Science
International Journal of Oral Science
Orofacial pain or tenderness is a primary symptom associated with temporomandibular joint (TMJ) disorders (TMDs). To understand the pathological mechanisms underlying TMDs, several mouse models have been developed, including mechanical stimulus-induc
Publikováno v:
International Journal of Oral Science, Vol 12, Iss 1, Pp 1-6 (2020)
International Journal of Oral Science
International Journal of Oral Science
Bone tissue engineering has emerged as a promising alternative therapy for patients who suffer bone fractures or defects caused by trauma, congenital diseases or tumours. However, the reconstruction of bone defects combined with osteoporosis remains
Publikováno v:
International Journal of Oral Science, Vol 12, Iss 1, Pp 1-10 (2020)
International Journal of Oral Science
International Journal of Oral Science
The integrity of the basal stem cell layer is critical for epithelial homoeostasis. In this paper, we review the expression of oral mucosal stem cell markers (OM-SCMs) in oral submucous fibrosis (OSF), oral potentially malignant disorders (OPMDs) and
Publikováno v:
International Journal of Oral Science, Vol 12, Iss 1, Pp 1-12 (2020)
International Journal of Oral Science
International Journal of Oral Science
Radiotherapy is one of the most common treatments for oral cancer. However, in the clinic, recurrence and metastasis of oral cancer occur after radiotherapy, and the underlying mechanism remains unclear. Cancer stem cells (CSCs), considered the “se