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Autor:
Anja S. Petersen, Per Holm, Adam Sebastian Pedersen, Rigmor Jensen, Agneta Snoer, Mads Barloese, O. F. Pedersen
Publikováno v:
Headache: The Journal of Head and Face Pain. 62:26-35
OBJECTIVE To investigate the safety and efficacy of intranasal ketamine for the treatment of a single cluster headache (CH) attack. BACKGROUND Acute treatment options for patients with CH who have an insufficient response to oxygen and triptans are l
Autor:
Sheena K. Aurora, Paul Winner, Maria Jeleva, Timothy R. Smith, Jasna Hocevar-Trnka, Stephen B. Shrewsbury
Publikováno v:
Headache: The Journal of Head and Face Pain. 61:1214-1226
Objective To report the safety, tolerability, exploratory efficacy, and patient acceptability of INP104 for the acute treatment of migraine from the Phase 3 STOP 301 trial. Background Dihydroergotamine (DHE) has long been used to treat migraine, but
Publikováno v:
Headache: The Journal of Head and Face Pain. 61:603-611
Objective To compare the efficacy of intravenous chlorpromazine versus intravenous prochlorperazine for the treatment of acute migraine in adults presenting to the emergency department (ED). Background Migraine is a common, incapacitating neurologica
Autor:
Matthew S. Robbins, Andrew Williams, Eddie Irizarry, Eleftheria Zias, Benjamin W. Friedman, Clemencia Solorzano, Michael Del Valle, E. John Gallagher, Melissa A. Harrilal, Polly E. Bijur
Publikováno v:
Headache: The Journal of Head and Face Pain. 60:2380-2388
Background Greater occipital nerve blocks (GONB) are used increasingly to treat acute migraine. Objective We conducted a randomized controlled trial to determine whether GONB was as effective as intravenous metoclopramide for migraine. Methods This w
Publikováno v:
Headache: The Journal of Head and Face Pain. 60:1939-1946
Objective To evaluate the pharmacokinetics, safety, and tolerability of a single 50-mg oral dose of diclofenac potassium for oral solution (OS) in a pediatric cohort with a diagnosis of episodic migraine; the 3-month safety trial following an outpati
Autor:
Ole Solheim, Sasha Gulati, David W. Dodick, Erling Tronvik, Joan Vidal Crespi, Daniel Fossum Bratbak, Erik Magnus Berntsen, Manjit Matharu
Publikováno v:
Headache: The Journal of Head and Face Pain. 60:1632-1643
Background The otic ganglion (OG) provides parasympathetic innervation to the cerebral circulation and cranial structures and may be involved in the pathophysiology of trigeminal autonomic headaches. This structure has never been targeted in any head
Publikováno v:
Headache
Objective To investigate and compare the safety and the pharmacokinetics of dihydroergotamine (DHE) after administration of intranasal DHE powder (STS101), intranasal DHE spray (Migranal® ), and intramuscular (IM) DHE injection in healthy subjects.
Publikováno v:
Headache: The Journal of Head and Face Pain. 59:394-409
Objective Investigate the safety and pharmacokinetics (PK) of INP104, intranasal dihydroergotamine mesylate (DHE) administered via a Precision Olfactory Delivery (POD® ) device, (Impel NeuroPharma, Seattle, WA) vs intravenous (IV) DHE and DHE nasal
Publikováno v:
Headache
Objectives To investigate long-term outcomes in per-protocol chronic cluster headache patients (n = 7), 18 and 24 months after participation in "Pilot study of sphenopalatine injection of onabotulinumtoxinA for the treatment of intractable chronic cl
Autor:
Todd D. Rozen
Publikováno v:
Headache: The Journal of Head and Face Pain. 59:56-62
Objective To determine the efficacy of high-volume anesthetic suboccipital nerve blocks (HVSON) for chronic cluster headache (CCH) and to define consistency of response over long-term use. Background There are studies showing efficacy of greater occi