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Autor:
Gareth P. Gregory, Carolyn Shembrey, Izabela Todorovski, Ricky W. Johnstone, Thomas Abrehart, Giovanna Pomilio, Kristin K. Brown, Emily Gruber, Andrew H. Wei, Stefan Bjelosevic, Andrea Newbold, Stephin J. Vervoort
Publikováno v:
Experimental Hematology. 88:S37-S38
Mutations in the FMS-like tyrosine kinase 3 (FLT3) gene occur in approximately 30% of all acute myeloid leukaemias (AMLs) and are associated with poor prognosis. The clinical utility of FLT3 inhibitor monotherapy has been limited by the rapid develop