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Publikováno v:
Experimental and Therapeutic Medicine
Long non-coding RNAs (lncRNAs) serve a crucial role in every aspect of cell biological functions as well as in a variety of diseases, including cardiovascular disease, cancer and nervous system disease. However, the differential expression profiles o
Autor:
Yonglin Wu, Yanzhao Qiu
Publikováno v:
Experimental and Therapeutic Medicine
Hydrocephalus is among the most common pediatric conditions treated by neurosurgeons. An antibiotic-impregnated shunt (AIS) was designed to reduce the rate of shunt infections. The objective of this systematic review and meta-analysis was to assess t
Publikováno v:
Experimental and Therapeutic Medicine
The present study investigated the effect of long non-coding RNA (lncRNA) Dlx6os1 silencing on cell proliferation, apoptosis and fibrosis, and further explored its influence on the mRNA expression profile in mouse mesangial cells (MMCs) of a diabetic
Publikováno v:
Experimental and Therapeutic Medicine
To investigate the molecular mechanism underlying the interaction between autophagosomes of alveolar type II epithelial (A549) cells and Klebsiella pneumoniae, an in vitro model of K. pneumoniae-infected A549 cells was established. Western blot analy
Publikováno v:
Experimental and Therapeutic Medicine
The metastatic behavior of hepatocellular carcinoma (HCC) is one of the key factors that leads to poor prognosis. The aim of the current study was to determine the changes in metastasis and the proliferation potential of bone marrow mesenchymal stem
Publikováno v:
Experimental and Therapeutic Medicine
Transforming growth factor β1 (TGF-β1) can promote the proliferation and differentiation of intervertebral disc cells and participates in its repair process. However, whether TGF-β1 engages in the process of disc degeneration has not yet been full
Publikováno v:
Experimental and Therapeutic Medicine
The current study aimed to investigate the imaging manifestations of vertebral aneurysmal bone cyst (ABC), and examine the clinical value of interventional embolization. Imaging examinations of 5 patients with pathologically confirmed spinal ABC were
Publikováno v:
Experimental and Therapeutic Medicine
Doxorubicin (DOX) has been widely employed to treat cancer, particularly solid tumors and hematological malignancies, owing to its high efficacy; however, chemotherapy has been indicated to be cardiotoxic and induce adverse effects, including mitocho
Autor:
Rui Han, Dong‑You Zhang, Yi Yang, Shuang Zhang, Hai‑Feng Liu, Jun Fu, Pian‑Pian Huang, Qing‑Dong Yao
Publikováno v:
Experimental and Therapeutic Medicine
The present study aimed to evaluate the value of serum amyloid A (SAA) in coronavirus disease 2019 (COVID-19) and compared the efficacy of SAA and C-reactive protein (CRP) in predicting the severity and recovery of COVID-19. A retrospective study was
Autor:
Qin Xiong, Yan‑Yu Yang, Min Tan, Quan‑Bo Zhang, Tao‑Hong Liu, Jian‑Xiong Zheng, Yu‑Feng Qing, Wen-Jun Zhou
Publikováno v:
Experimental and Therapeutic Medicine
The present study aimed to investigate the expression and significance of the mRNA of genes associated with autophagy and long non-coding RNA (lncRNA) GAS5 in peripheral blood mononuclear cells (PBMCs) of patients with ankylosing spondylitis (AS). Th