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Autor:
Jing Zhao, Han Xiao, Ping Liang, Ning Jiang, Li Zhang, Shuyue Zheng, Hui Gan, Xuan Zhai, Hui Chen, Lu Wang
Publikováno v:
Experimental and Molecular Medicine, Vol 53, Iss 11, Pp 1807-1818 (2021)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
The NLRC4 inflammasome, a member of the nucleotide-binding and oligomerization domain-like receptor (NLR) family, amplifies inflammation by facilitating the processing of caspase-1, interleukin (IL)–1β, and IL-18. We explored whether NLRC4 knockdo
Autor:
Jong Gil Park, Sinai Kim, Sang Hak Lee, Goo Taeg Oh, In Hyuk Jung, Na Young Ko, Se Jin Jeong, Jeong Ki Min, Min Ji Cho
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 9, Pp 1587-1601 (2020)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
Abdominal aortic aneurysm (AAA) is an inflammatory vascular disease characterized by structural deterioration of the aorta caused by inflammation and oxidative stress, leading to aortic dilatation and rupture. Peroxiredoxin 2 (PRDX2), an antioxidant
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 5, Pp 843-853 (2020)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
Angiogenesis and synoviocyte hyperplasia, called ‘pannus,’ are pathologic hallmarks of rheumatoid arthritis (RA). To determine the clinical significance of angiogenic cytokines in RA, the levels of pro-angiogenic cytokines, including VEGF, placen
Autor:
Thi Bich Tra Cao, Quoc Quang Luu, Seung-Hyun Kim, Thuy Van Thao Nguyen, Seo-Hee Kim, Hae-Sim Park, Hoang Kim Tu Trinh
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 2, Pp 253-265 (2020)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
Patients with late-onset asthma (LOA) have poor clinical outcomes. Osteopontin (OPN) is associated with airway inflammation and remodeling. To investigate the role of OPN in LOA compared to early-onset asthma (EOA), serum OPN levels were compared bet
Autor:
Je-Yong Choi
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 8, Pp 1165-1165 (2020)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
Autor:
Cristina Richie
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 11, Pp 1-1 (2019)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
Osteoporosis develops with high prevalence in both postmenopausal women and hypogonadal men. Osteoporosis results in significant morbidity, but no cure has been established. Mesenchymal stem cells (MSCs) critically contribute to bone homeostasis and