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Publikováno v:
Experimental & Molecular Medicine
The intracellular parasite Toxoplasma gondii has unique dense granule antigens (GRAs) that are crucial for host infection. Emerging evidence suggests that GRA8 of T. gondii is a promising serodiagnostic marker in toxoplasmosis. However, little is kno
Publikováno v:
Experimental & Molecular Medicine
Embryonic stem cells (ESCs) are metabolically distinct from their differentiated counterparts. ESC mitochondria are less complex and fewer in number than their differentiated progeny. However, few studies have examined the proteins responsible for di
Autor:
Dong Hyun Kim, Eun Ji Song, Moonkyung Kang, Yeon-Soo Kim, Inhee Mook-Jung, Dong Woo Nam, Minho Moon, Seong Gak Jeon
Publikováno v:
Experimental & Molecular Medicine
Progressive cognitive declines are the main clinical symptoms of Alzheimer’s disease (AD). Cognitive impairment in AD is directly correlated with amyloid beta (Aβ)-mediated synaptic deficits. It is known that upregulation of neurogranin (Ng), a po
Publikováno v:
Experimental & Molecular Medicine
Nervous wreck (Nwk), a protein that is present at Type 1 glutamatergic synapses that contains an SH3 domain and an FCH motif, is a Drosophila homolog of the human srGAP3/MEGAP protein, which is associated with mental retardation. Confocal microscopy
Autor:
Ji-Hoi Moon, Sung-Hwan Park, Yoojun Nam, Juryun Kim, Yeonsue Jang, Yeri Alice Rim, Yena Kim, Seung Min Jung, Hyerin Jung, Ji Hyeon Ju, Kijun Lee, Sang Hoon Jeong, Seung-Jin Choi, Narae Park
Publikováno v:
Experimental & Molecular Medicine
Rheumatoid arthritis (RA) is a chronic autoimmune disease that typically results in strong inflammation and bone destruction in the joints. It is generally known that the pathogenesis of RA is linked to cardiovascular and periodontal diseases. Though
Autor:
Ding-Feng Su, Yang Sun, Zhu-Min Luo, Xia Liu, Yili Yang, Zhen Qin, Jing-Jing Wan, Bo-Han Hu, Jian-Guang Yu, Peng-Yuan Wang
Publikováno v:
Experimental & Molecular Medicine
Gender differences in fatigue manifest as females being more prone to feel exhaustion and having lower muscle endurance. However, the mechanisms of these effects remain unclear. We investigated whether orosomucoid, an endogenous anti-fatigue protein
Autor:
Tineke E. Buffart, Dennis Poel, Jolanda E. W. Oosterling-Jansen, Jens Voortman, Henk M.W. Verheul
Publikováno v:
Experimental & Molecular Medicine
Poel, D, Buffart, T E, Oosterling-Jansen, J, Verheul, H M & Voortman, J 2018, ' Evaluation of several methodological challenges in circulating miRNA qPCR studies in patients with head and neck cancer ', Experimental & Molecular Medicine, vol. 50, no. 3, pp. e454 . https://doi.org/10.1038/emm.2017.288
Experimental & Molecular Medicine, 50(3). Korean Society of Med. Biochemistry and Mol. Biology
Poel, D, Buffart, T E, Oosterling-Jansen, J, Verheul, H M & Voortman, J 2018, ' Evaluation of several methodological challenges in circulating miRNA qPCR studies in patients with head and neck cancer ', Experimental & Molecular Medicine, vol. 50, no. 3, pp. e454 . https://doi.org/10.1038/emm.2017.288
Experimental & Molecular Medicine, 50(3). Korean Society of Med. Biochemistry and Mol. Biology
Circulating microRNAs (ci-miRNAs) in blood have emerged as promising diagnostic, prognostic and predictive biomarkers in cancer. Many clinical studies currently incorporate studies that assess ci-miRNAs. Validation of the clinical significance of can
Autor:
Yen-You Lin, Wu-Fu Chen, Chun-Sung Sung, Chieh-Yu Pan, Chien-Wei Feng, Han-Chun Hung, Kuan-Hao Tsui, Zhi-Hong Wen, Chun-Hong Chen, Jyh-Horng Sheu
Publikováno v:
Experimental & Molecular Medicine
Atopic dermatitis (AD) is a chronic inflammatory skin disease, and its prevalence is increasing. AD usually elicits skin barrier dysfunction, dry skin and itching. As the mechanisms of AD remain unknown, there is an urgent need to find effective ther
Publikováno v:
Experimental & Molecular Medicine
In a previous study, we screened thousands of long non-coding RNAs (lncRNAs) to assess their potential relationship with congenital heart disease (CHD). In this study, uc.4 attracted our attention because of its high level of evolutionary conservatio
Autor:
Dan Luo, Haichao Wang, Qisheng Zheng, Yuan Li, Li-xin Zhou, Ming Cui, Shuyi Zhao, Huiwen Xiao, Jiali Dong, Saijun Fan
Publikováno v:
Experimental & Molecular Medicine
Although radiation therapy is a cornerstone of modern management of malignancies, various side effects are inevitably linked to abdominal and pelvic cancer after radiotherapy. Radiation-mediated gastrointestinal (GI) toxicity impairs the life quality