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Publikováno v:
Experimental & Molecular Medicine
Impaired angiogenesis is one of the crucial factors that impede the wound healing process in diabetic foot ulcers (DFUs). In this study, we found that 20(S)-protopanaxadiol (PPD), an aglycone of ginsenosides in Panax notoginseng, stimulated angiogene
Autor:
Hye Yeon Park, Myungchull Rhee, Takuya Murata, Jae-Ran Lee, Kyoung Shim Kim, Young Jun Kang, Yoon-Jung Kim, Hyun-Jun Lee, Dae Yeul Yu, Bong Hyun Chung, Yong-Hoon Kim, Jung Hwan Hwang, Chul-Ho Lee, Yoichi Gondo, Pyung Lim Han
Publikováno v:
Experimental & Molecular Medicine
Striatal-enriched protein tyrosine phosphatase (STEP) is abundantly expressed in the striatum, which strongly expresses dopamine and opioid receptors and mediates the effects of many drugs of abuse. However, little is known about the role of STEP in
Autor:
Ja Kyung Kim, Junjeong Choi, Jung Il Lee, Su Yeon Lee, Hye Young Chang, Kwan Sik Lee, Dong Ki Lee
Publikováno v:
Experimental & Molecular Medicine
Nonalcoholic steatohepatitis (NASH) can progress into liver cirrhosis; however, no definite treatment is available. Omega-3 polyunsaturated fatty acid (omega-3) has been reported to alleviate experimental NASH, although its beneficial effect was not
Autor:
Jae-Ha Ryu, Hui-Yuan Zhao, Sang-Myeong Lee, Ui-Jin Bae, Young-Rae Lee, Seong Ji Woo, Jae Do Yang, Hee Chul Yu, Baik Hwan Cho, Jeung-Hyun Koo, Byung-Hyun Park, Raok Jeon, Sun-O Ka
Publikováno v:
Experimental & Molecular Medicine
Hepatic ischemia/reperfusion (I/R) injury leads to oxidative stress and acute inflammatory responses that cause liver damage and have a considerable impact on the postoperative outcome. Much research has been performed to develop possible protective
Publikováno v:
Experimental & Molecular Medicine
Gastric cancer overexpressing the human epidermal growth factor 2 (HER2) protein has a poor outcome, although a combination of chemotherapy and the anti-HER2 antibody trastuzumab has been approved for the treatment of advanced gastric cancer. Vascula