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Publikováno v:
European Neuropsychopharmacology. 37:29-38
There is insufficient data regarding the excess direct and indirect costs associated with attention deficit hyperactivity disorder (ADHD). Using the Danish National Patient Registry (2002-2016), we identified 83,613 people of any age with a diagnosis
Autor:
David Coghill, Ching-Lung Cheung, Grace Mengqin Ge, Gloria H.Y. Li, Ian C. K. Wong, Patrick Ip
Publikováno v:
European Neuropsychopharmacology. 37:49-63
In a retrospective cohort study, patients with attention-deficit hyperactivity disorder (ADHD) and psychostimulant prescription were associated with increased risk of Parkinson's disease (PD). It is unclear whether ADHD per se or psychostimulant pres
Autor:
Martin Heinze, Stefan Bleich, Renate Grohmann, Philipp Pauwels, Michael Schneider, Timo Greiner, Sermin Toto
Publikováno v:
European Neuropsychopharmacology. 36:60-71
Severe weight gain induced by psychotropics is a known problem in psychiatry. Various drugs from different classes may lead to weight gain that may further lead to potentially life-shortening diseases, such as diabetes or cardiovascular disease. A to
Autor:
Binoy Varghese Cheriyan, Vijaykumar Sayeli, Jagan Nadipelly, Parimala Kathirvelu, Viswanathan Subramanian, Jaikumar Shanmugasundaram
Publikováno v:
European Neuropsychopharmacology. 36:100-110
Anxiety disorders are common worldwide and novel compounds are investigated for anxiolytic effect. A few studies have demonstrated the anxiolytic-like activity of natural and synthetic flavonoids. 5-methoxyflavone, a synthetic flavone derivative, has
Autor:
Jean-Martin Beaulieu, Christian Ole Wächtler, Karima Chakroun, Nora Hennies, Mareike Clos, Tobias Sommer, Janine Bayer
Publikováno v:
European Neuropsychopharmacology. 35:126-135
D2 autoreceptors provide an important regulatory mechanism of dopaminergic neurotransmission. However, D2 receptors are also expressed as heteroreceptors at postsynaptic membranes. The expression and the functional characteristics of both, D2 auto- a
Autor:
Claudia Pisanu, Alessio Squassina, Paola Niola, Donatella Congiu, Cristiana Cruceanu, Martin Alda, Maria Del Zompo, Raffaella Ardau, Giovanni Severino, Juan Pablo Lopez, Gustavo Turecki, Caterina Chillotti
Publikováno v:
European Neuropsychopharmacology. 34:39-49
Post-mortem brain studies suggest that miRNAs may be involved in suicide, but their role as peripheral biomarkers or targets of preventive pharmacological treatments in suicide has yet to be elucidated. We used nCounter miRNA Expression assay to meas
Autor:
Paola Bucci, Paola Dazzan, Giulia Maria Giordano, Carmen Aiello, Silvana Galderisi, Celso Arango, Lone Baandrup, Inge Winter van Rossum, René S. Kahn, Roberto Rodriguez-Jimenez, Arsime Demjaha, Covadonga M. Díaz-Caneja, Robert W. Buchanan, Stefan Leucht, A. Vignapiano, Birte Glenthøj, Philip McGuire, Armida Mucci
Publikováno v:
European Neuropsychopharmacology. 34:76-86
Negative symptoms are associated with poor clinical and psychosocial outcome in schizophrenia. Their prevalence and identification in first-episode patients remains controversial. In a large cohort of patients in the early stage of schizophrenia, sch
Autor:
Andrew E. Huff, Boyer D. Winters, Michael Wolter, Zoey Pulles, Nana Baidoo, Francesco Leri, Kristen H. Jardine
Publikováno v:
European Neuropsychopharmacology. 33:146-157
There is recent evidence that cocaine, nicotine, and their conditioned stimuli have the ability to enhance memory consolidation. The present study compared the effects of post-training heroin and of a heroin contextual conditioned stimulus (CS+) on c
Autor:
Simona Scheggi, Gabriele Floris, Marco Orrù, Beth Levant, Hunter J. Strathman, Marco Bortolato
Publikováno v:
European Neuropsychopharmacology. 32:104-119
Pramipexole (PPX) is a D2 and D3 dopamine receptor agonist approved for clinical use, which is associated with a higher risk of impulse-control disorders. Using a rat model, we recently found that low doses of the monoamine-depleting agent reserpine
Autor:
Stephan Heres, Mark Weiser, Mor Bar Haim, Inge Winter van Rossum, Shimon Burshtein, Geva Shenkman, Michael Davidson, René S. Kahn, Linda Levi
Publikováno v:
European Neuropsychopharmacology. 32:131-135
Some, but not all, studies have found longer duration of untreated psychosis (DUP) to be associated with poor response to treatment and more severe negative symptoms in schizophrenia. The aim of the current analysis was to investigate these parameter