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Autor:
Michele Verde-Ramo Soares, Alana Gomes de Souza, Adriano José Maia Chaves Filho, Danielle Silveira Macêdo, Tatiana de Queiroz, Paloma Marinho Jucá, Natássia Lopes Cunha, Carolina Horta Andrade, Dino César da Silva Clemente, Melina Mottin, Christina Alves Peixoto, Patrícia de Araújo Rodrigues
Publikováno v:
European Neuropsychopharmacology. 42:57-74
Immune-inflammatory mechanisms are involved in the pathophysiology of bipolar disorder. Tetracyclines present neuroprotective actions based on their anti-inflammatory and microglia suppressant effects. Doxycycline (DOXY) is a tetracycline that demons
Autor:
Nídia Fernandez Ros, Elham Jaberi, Brice Ozenne, Kristian Linnet, Shohreh Issazadeh-Navikas, Hanne D. Hansen, Lene Lundgaard Donovan, Sys Stybe Johansen, Gitte M. Knudsen, Jens Vilstrup Johansen
Publikováno v:
European Neuropsychopharmacology. 42:1-11
Psilocybin has in some studies shown promise as treatment of major depressive disorder and psilocybin therapy was in 2019 twice designated as breakthrough therapy by the U.S. Food and Drug Administration (FDA). A very particular feature is that inges
Autor:
Xianjin Zhou, Jared W. Young, Baohu Ji, Jordy van Enkhuizen, Benjamin Z Roberts, Molly A. Kwiatkowski
Publikováno v:
Eur Neuropsychopharmacol
Bipolar disorder (BD) is a severe mental illness affecting 2% of the global population. Current pharmacotherapies provide incomplete symptom remediation, highlighting the need for novel therapeutics. BD is characterized by fluctuations between mania
Publikováno v:
European Neuropsychopharmacology. 41:63-69
Clozapine is the only antipsychotic compound indicated for refractory-schizophrenia. However, it is associated with emergent metabolic dysregulation and cardiovascular risk which may lead to mortality. In this study we aimed to explore predictors for
Autor:
Nisha Singh, Amanda Kiemes, Diana Cash, Gemma Modinos, Anthony C. Vernon, Alba Peris-Yague, Marie-Caroline Cotel
Publikováno v:
European Neuropsychopharmacology. 41:106-117
Post-mortem studies suggest that schizophrenia is associated with abnormal expression of specific GABAA receptor (GABAAR) α subunits, including α5GABAAR. Positron emission tomography (PET) measures of GABAAR availability in schizophrenia, however,
Autor:
Yukihiro Noda, Yuko Arioka, Mizuki Uchida, Akihiro Mouri, Takayoshi Mamiya, Norio Ozaki, Shokuro Yamada, Shinji Kitagaki, Itaru Kushima, Akira Yoshimi, Sakika Goto
Publikováno v:
European Neuropsychopharmacology. 41:92-105
The smoking incentive in patients with schizophrenia (SCZ) depends on stimulation of nicotinic acetylcholine receptors (nAChRs) in the central nervous system. To detect potential predictor genes for nicotine responses in SCZ, we explored common facto
Autor:
Maya Amitai, Maya Lebow, Silvana Fennig, Michal Taler, Alan Apter, Alon Chen, Reut Ben-Baruch, Abraham Weizman
Publikováno v:
European Neuropsychopharmacology. 40:61-69
Major depressive disorder (MDD) is associated with alterations in circulatory cytokines, in adults as well as in children and adolescents. Administration of selective serotonin reuptake inhibitors (SSRIs) to MDD pediatric patients modifies cytokine l
Autor:
Jacqueline Mayoral-van Son, Victor Ortiz-García de la Foz, Rosa Ayesa Arriola, Javier Vázquez-Bourgon, Miguel Ibañez Alario, Marcos Gómez Revuelta, Benedicto Crespo Facorro, María Juncal Ruiz
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Schizophrenia is a severe brain disorder with an excess morbidity and mortality partly due to a higher incidence of metabolic disturbances and cardio-vascular events. The exposure to antipsychotic treatment has been observed linked to these metabolic
Autor:
Parianen Lesemann, Franca H., Spencer, Hannah, Montoya, Estrella R., Kraaijenvanger, Eline J., He, Yujie, Branje, Susan, Boks, Marco P., Bos, Peter A., Leerstoel Honk, Experimental Psychology (onderzoeksprogramma PF), Helmholtz Institute, Leerstoel Branje, Adolescent development: Characteristics and determinants
Publikováno v:
European Neuropsychopharmacology, 39, 19. Elsevier
European Neuropsychopharmacology, 39, 19-28. Elsevier
European Neuropsychopharmacology, 39, 19-28. Elsevier
Childhood trauma fundamentally shapes social cognition and basic processing of social cues, which frequently cascade into adverse behavioral outcomes. Recent studies indicate that epigenetic changes in oxytocin functioning might contribute to these l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f647634d42081d3e955fef70d93b94
https://dare.uva.nl/personal/pure/en/publications/methylation-of-oxytocin-related-genes-and-early-life-trauma-together-shape-the-n170-response-to-human-faces(3a565245-0d37-442c-b375-de807036d0b1).html
https://dare.uva.nl/personal/pure/en/publications/methylation-of-oxytocin-related-genes-and-early-life-trauma-together-shape-the-n170-response-to-human-faces(3a565245-0d37-442c-b375-de807036d0b1).html
Publikováno v:
European Neuropsychopharmacology. 38:63-72
Transcranial direct current stimulation (tDCS) induces polarity-dependent neuroplasticity: with conventional protocols, anodal tDCS results in excitability enhancement while cathodal stimulation reduces excitability. However, partially non-linear res