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Autor:
Eduard Vieta, Christopher Gaudiot, Ross J. Baldessarini, Mauricio Tohen, Yiliang Zhu, Anastasiya Nestsiarovich
Publikováno v:
European Neuropsychopharmacology. 54:75-89
Uncertainty remains regarding the relative efficacy of maintenance pharmacotherapy for bipolar disorder (BD), and available data require updating. The present systematic review and meta-analysis aims to consolidate the evidence from the highest quali
Autor:
Natalie T. Mills, Hikaru Hori, Scott R. Clark, Célia Fourrier, Bernhard T. Baune, Jennie Louise, K Oliver Schubert, Emma Sampson
Publikováno v:
European Neuropsychopharmacology. 53:34-46
Given the role of low-grade inflammation in the pathophysiology of major depressive disorder (MDD), anti-inflammatory strategies may improve treatment outcomes in some patients. However, it is controversial whether they can be used as adjunctive trea
Autor:
Bindu M. Kutty, Monojit Debnath, Ganesan Venkatasubramanian, Michael Maes, Michael Berk, Fazal Abdul, Pinku Mani Talukdar
Publikováno v:
European Neuropsychopharmacology. 52:48-61
Infection, particularly prenatal infection leads to an enhanced risk of schizophrenia in the offspring. Interestingly, few data exist on the pathway(s) such as TLR and inflammasome, primarily involved in sensing the microorganisms and inducing downst
Autor:
Esther Berrocoso, Manuel Desco, Juan Antonio Mico, Laura Perez-Caballero, M.L. Soto-Montenegro
Publikováno v:
European Neuropsychopharmacology. 51:1-6
Escitalopram is a selective serotonin reuptake inhibitor (SSRIs) antidepressant, drug that is currently used as first-line agents for the treatment of depression and it is also used in the treatment of other psychiatric disorders. The main goal of th
Publikováno v:
European Neuropsychopharmacology. 51:90-104
Daridorexant (ACT-541468) is a new dual orexin receptor antagonist being evaluated for the treatment of insomnia, which is a common comorbidity of depression and anxiety. Therefore, daridorexant is likely to be administered concomitantly with agents
Autor:
Christiane Mühle, Valery Grinevich, Johannes Kornhuber, Patrick Bach, Christian Weinland, Falk Kiefer, Bernd Lenz, Iulia Zoicas
Publikováno v:
European Neuropsychopharmacology. 51:55-67
Alcohol use disorder (AUD) is a severe illness, for which we lack sufficient mechanistic understanding. Preliminary evidence associates AUD with the oxytocin (OXT) system. Here we investigated alterations in endogenous OXT blood concentrations in pat
Autor:
Martin K. Madsen, Dea S. Stenbæk, Sys Stybe Johansen, Patrick M. Fisher, Albin Arvidsson, Sophia Armand, Kristian Linnet, Gitte Maegaard Knudsen, Brice Ozenne, Maja Rou Marstrand-Joergensen
Publikováno v:
Madsen, M K, Stenbæk, D S, Arvidsson, A, Armand, S, Marstrand-Joergensen, M R, Johansen, S S, Linnet, K, Ozenne, B, Knudsen, G M & Fisher, P M 2021, ' Psilocybin-induced changes in brain network integrity and segregation correlate with plasma psilocin level and psychedelic experience ', European Neuropsychopharmacology, vol. 50, pp. 121-132 . https://doi.org/10.1016/j.euroneuro.2021.06.001
The emerging novel therapeutic psilocybin produces psychedelic effects via engagement of cerebral serotonergic targets by psilocin (active metabolite). The serotonin 2A receptor critically mediates these effects by altering distributed neural process
Publikováno v:
European Neuropsychopharmacology. 50:75-92
Considering the global increase in use of Z-drugs to treat insomnia, the study objective was to conduct a systematic review on the efficacy and safety of zopiclone to treat sleep disorders in older adults compared to other sedative-hypnotics, to plac
Autor:
Claudia da Costa Leite, Márcio Gerhardt Soeiro-de-Souza, E. Scotti-Muzzi, Fernando Fernandes, Rodrigo Machado-Vieira, R. T. De Sousa, Maria Concepcion Garcia Otaduy
Publikováno v:
European Neuropsychopharmacology. 49:93-100
The diagnosis and treatment of bipolar depression (BDep) poses complex clinical challenges for psychiatry. Proton magnetic resonance spectroscopy (1H-MRS) is a useful imaging tool for investigating in vivo levels of brain neuro-metabolites, critical
Autor:
Thomas Habekost, Julijana le Sommer, Birte Glenthøj, Signe Vangkilde, Bob Oranje, Birgitte Fagerlund, Jens Richardt Møllegaard Jepsen, Ann-Marie Low
Publikováno v:
European Neuropsychopharmacology. 46:83-92
Deficient information processing in ADHD theoretically results in sensory overload, which in turn may underlie its symptoms. If this sensory overload is caused by deficient filtering of environmental stimuli, then one would expect finding deficits in