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Autor:
Binoy Varghese Cheriyan, Vijaykumar Sayeli, Jagan Nadipelly, Parimala Kathirvelu, Viswanathan Subramanian, Jaikumar Shanmugasundaram
Publikováno v:
European Neuropsychopharmacology. 36:100-110
Anxiety disorders are common worldwide and novel compounds are investigated for anxiolytic effect. A few studies have demonstrated the anxiolytic-like activity of natural and synthetic flavonoids. 5-methoxyflavone, a synthetic flavone derivative, has
Autor:
Jean-Martin Beaulieu, Christian Ole Wächtler, Karima Chakroun, Nora Hennies, Mareike Clos, Tobias Sommer, Janine Bayer
Publikováno v:
European Neuropsychopharmacology. 35:126-135
D2 autoreceptors provide an important regulatory mechanism of dopaminergic neurotransmission. However, D2 receptors are also expressed as heteroreceptors at postsynaptic membranes. The expression and the functional characteristics of both, D2 auto- a
Autor:
Claudia Pisanu, Alessio Squassina, Paola Niola, Donatella Congiu, Cristiana Cruceanu, Martin Alda, Maria Del Zompo, Raffaella Ardau, Giovanni Severino, Juan Pablo Lopez, Gustavo Turecki, Caterina Chillotti
Publikováno v:
European Neuropsychopharmacology. 34:39-49
Post-mortem brain studies suggest that miRNAs may be involved in suicide, but their role as peripheral biomarkers or targets of preventive pharmacological treatments in suicide has yet to be elucidated. We used nCounter miRNA Expression assay to meas
Autor:
Paola Bucci, Paola Dazzan, Giulia Maria Giordano, Carmen Aiello, Silvana Galderisi, Celso Arango, Lone Baandrup, Inge Winter van Rossum, René S. Kahn, Roberto Rodriguez-Jimenez, Arsime Demjaha, Covadonga M. Díaz-Caneja, Robert W. Buchanan, Stefan Leucht, A. Vignapiano, Birte Glenthøj, Philip McGuire, Armida Mucci
Publikováno v:
European Neuropsychopharmacology. 34:76-86
Negative symptoms are associated with poor clinical and psychosocial outcome in schizophrenia. Their prevalence and identification in first-episode patients remains controversial. In a large cohort of patients in the early stage of schizophrenia, sch
Autor:
Andrew E. Huff, Boyer D. Winters, Michael Wolter, Zoey Pulles, Nana Baidoo, Francesco Leri, Kristen H. Jardine
Publikováno v:
European Neuropsychopharmacology. 33:146-157
There is recent evidence that cocaine, nicotine, and their conditioned stimuli have the ability to enhance memory consolidation. The present study compared the effects of post-training heroin and of a heroin contextual conditioned stimulus (CS+) on c
Autor:
Simona Scheggi, Gabriele Floris, Marco Orrù, Beth Levant, Hunter J. Strathman, Marco Bortolato
Publikováno v:
European Neuropsychopharmacology. 32:104-119
Pramipexole (PPX) is a D2 and D3 dopamine receptor agonist approved for clinical use, which is associated with a higher risk of impulse-control disorders. Using a rat model, we recently found that low doses of the monoamine-depleting agent reserpine
Autor:
Stephan Heres, Mark Weiser, Mor Bar Haim, Inge Winter van Rossum, Shimon Burshtein, Geva Shenkman, Michael Davidson, René S. Kahn, Linda Levi
Publikováno v:
European Neuropsychopharmacology. 32:131-135
Some, but not all, studies have found longer duration of untreated psychosis (DUP) to be associated with poor response to treatment and more severe negative symptoms in schizophrenia. The aim of the current analysis was to investigate these parameter
Autor:
Emanuele Cassioli, Lisa Lazzeretti, E. Calderani, Francesco Rotella, Benedetta Ragghianti, Edoardo Mannucci, Valdo Ricca
Publikováno v:
European Neuropsychopharmacology. 32:56-65
Most of the randomized controlled trials (RCTs) on antipsychotics (APs) have efficacy as their primary endpoint, leading to a lack of evidence on long-term metabolic effects of APs. The aim of the present meta-analysis is to compare different APs for
Autor:
Marilise Escobar Burger, H.J. Segat, Verônica Tironi Dias, H.Z. Rosa, Laura Hautrive Milanesi, Kr. Roversi, Raquel Cristine Silva Barcelos
Publikováno v:
European Neuropsychopharmacology. 32:25-35
Addiction is a devastating worldwide disorder that requires effective and innovative therapies. Physical exercise could be useful in addiction treatment because it shares a common neural circuit with addictive drugs. Based on this, molecular adaptati
Autor:
Maryam Ardalan, Ali Rafati, Monireh Mansouri, Betina Elfving, Carlos A. Zarate, Aleksander A. Mathé, Gregers Wegener
Publikováno v:
Ardalan, M, Elfving, B, Rafati, A H, Mansouri, M, Zarate, C A, Mathe, A A & Wegener, G 2020, ' Rapid effects of S-ketamine on the morphology of hippocampal astrocytes and BDNF serum levels in a sex-dependent manner ', European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, vol. 32, pp. 94-103 . https://doi.org/10.1016/j.euroneuro.2020.01.001
Eur Neuropsychopharmacol
Eur Neuropsychopharmacol
The prevalence of major depressive disorder (MDD) is higher in women than men. Importantly, a differential behavioral response by sex to the antidepressant response to ketamine in rodents has been reported. Mechanistically, male depressed-like animal