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Publikováno v:
European Neuropsychopharmacology. 43:38-51
Cannabinoids produce both rewarding and aversive effects in humans and experimental animals. However, the mechanisms underlying these conflicting findings are unclear. Here we examined the potential involvement of CB1 and CB2 receptors in cannabinoid
Autor:
Daniil Grinchii, Eliyahu Dremencov, Ruslan Paliokha, Lubica Lacinova, Daniela Jezova, Kristina Csatlosova, Barbora Durisova, Eszter Bögi, Lucia Moravcikova
Publikováno v:
European Neuropsychopharmacology. 43:82-91
Higher risk of depression and schizophrenia in descendants of mothers experienced acute infection during the pregnancy has been reported. Since monoamines are fundamental in mentioned psychopathologies, it is possible that maternal immune activation
Autor:
Xianjin Zhou, Jared W. Young, Baohu Ji, Jordy van Enkhuizen, Benjamin Z Roberts, Molly A. Kwiatkowski
Publikováno v:
Eur Neuropsychopharmacol
Bipolar disorder (BD) is a severe mental illness affecting 2% of the global population. Current pharmacotherapies provide incomplete symptom remediation, highlighting the need for novel therapeutics. BD is characterized by fluctuations between mania
Autor:
Natasha L. Mason, Eef L. Theunissen, Johannes G. Ramaekers, Peter Stiers, Stefan W. Toennes, Nadia R P W Hutten, Desmond H. Y. Tse
Publikováno v:
European Neuropsychopharmacology, 29(2), 247-256. Elsevier
Cannabis is the most commonly used illicit drug and is known to alter state of consciousness and impair neurocognitive function. However, the mechanisms underlying these effects have yet to be fully elucidated. Rodent studies suggest that Delta 9-tet
Autor:
Abanti Tagore, Sylvain Houle, Romina Mizrahi, Konstantine K. Zakzanis, Pablo Rusjan, Christin Schifani, Huai Hsuan Tseng, Naren P. Rao
Publikováno v:
European Neuropsychopharmacology. 29:1023-1032
Research suggests decreased cortical dopamine is a neural correlate of cognitive deficits in schizophrenia. Evidence of impaired cognitive task-induced cortical dopamine release was demonstrated in patients with psychosis. However, whether cortical d
Autor:
Sanders A. McDougall, Vanessa Gomez, Cynthia A. Crawford, Ginny I. Park, Goretti I. Ramirez, Brittnee C. Adame
Publikováno v:
Eur Neuropsychopharmacol
Although ketamine has long been known to increase locomotor activity, only recently was it realized that this behavioral effect varies according to both sex and age. The purpose of the present study was threefold: first, to measure the locomotor acti
Autor:
Sian M. J. Hemmings, Aqeedah Roomaney, Soraya Seedat, Leigh vd Heuvel, Jacqueline S. Womersley, Stefan S. du Plessis, Patricia Swart
Publikováno v:
European Neuropsychopharmacology. 51:e218-e219
Autor:
Ekrem Dere, Johannes Kornhuber, Teja W. Grömer, Christian P. Müller, Taygun C. Uzuneser, Stephan von Hörsten, Magnus Schindehütte
Publikováno v:
European Neuropsychopharmacology. 28:1382-1393
Schizophrenic patients suffer from various disruptions in their psyche, mood and cognition, most of which cannot be effectively treated with the available antipsychotic drugs. Some dimensions of the schizophrenia syndrome in man can be mimicked in an
Autor:
Basil Künnecke, Fabian Tollens, Adam J. Schwarz, Philipp Lebhardt, Wolfgang Weber-Fahr, Celine Risterucci, Robert Becker, Markus Sack, Natalia Gass, Andreas Meyer-Lindenberg, Jonathan Rochus Reinwald, Alexander Sartorius
Publikováno v:
European Neuropsychopharmacology. 28:1035-1046
One of the major challenges of cross-species translation in psychiatry is the identification of quantifiable brain phenotypes linked to drug efficacy and/or side effects. A measure that has received increasing interest is the effect of antipsychotic
Publikováno v:
European Neuropsychopharmacology. 28:933-944
Exerting cognitive control is an effortful endeavor that is strongly modulated by the availability of dopamine (DA) and norepinephrine (NE), which are both synthesized from the amino acid precursor tyrosine. Supplementing tyrosine may increase the sy