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Autor:
Jose C. Florez, Catherine Allard, Marie-France Hivert, Sarah Hsu, Alisa K. Manning, Camille E. Powe, Patrice Perron, Luigi Bouchard, Denise M. Scholtens, Alan Kuang, Miriam S. Udler, William Lowe
Publikováno v:
Diabetes. 69
Background: We previously described physiology-informed genetically-anchored type 2 diabetes (T2D) clusters based on associations between glycemic traits and T2D-associated variants discovered in prior GWAS. Cluster polygenic scores (PSs) delineate T
Publikováno v:
Diabetes. 38:291-303
Basal insulin supplementation has been used as a therapy for patients with non-insulin-dependent diabetes mellitus (NIDDM) who require insulin. To determine whether basal insulin supplementation in addition to lowering postabsorptive plasma glucose c