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pro vyhledávání: '"Smith, David A."'
Publikováno v:
Cephalalgia : an international journal of headache. 22(6)
5-HT1D (but not 5-HT1B)-receptor immunoreactivity (i.r.) can be detected on trigeminal fibres within the spinal trigeminal tract of the human brainstem. The present study used immunohistochemical and morphometric techniques to determine the proportio
Autor:
Dalip J. S. Sirinathsinghji, J. D. Pickard, George McAllister, R. Hopkins, A. J. Butler, Jenny Longmore, David R. Shaw, Raymond G. Hill, Smith David W
Publikováno v:
Cephalalgia : an international journal of headache. 17(8)
Sumatriptan, a 5HT1B/1D-receptor agonist, is clinically effective as an antimigraine agent. Its therapeutic action may result partly from vasoconstriction of excessively dilated cranial blood vessels (a 5HT1B-receptor mediated response). The antimigr