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Autor:
Xiaoyu Xia, Dongya Zhang, Yuchen Pan, Guoping Shi, Jingman Li, Yujun Xu, Dan Li, Li Lu, Yayi Hou, Huan Dou
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-13 (2021)
Cell Death Discovery
Cell Death Discovery
Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease. Myeloid-derived suppressor cells (MDSCs) have been found to be involved in the regulation of SLE development. However, little is known about the association between MDSC sub
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Cell Death Discovery
Cell Death Discovery
p53 and NF-κBp65 are essential transcription factors (TFs) in the cellular response to stress. Two signaling systems can often be entwined together and generally produce opposing biological outcomes in a cell context-dependent manner. Inhibitor of a
Autor:
Tomohiko Murase, Hiroaki Kajiyama, Yoshihiro Koya, Tomoko Nakamura, Satoko Osuka, Natsuki Nakanishi, Yukiyo Kasahara, Akira Iwase, Bayasula, Maki Goto, Nobuyoshi Takasaki
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-11 (2021)
Cell Death Discovery
Cell Death Discovery
Patients with primary ovarian insufficiency (POI) often have a high prevalence of autoimmune disorders. To identify antigenic molecules associated with ovarian autoimmunity, we performed immunoprecipitation (IP) screening using serum from patients wi
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Cell Death Discovery
Cell Death Discovery
Cell senescence is associated with age-related pathological changes. Increasing evidence has revealed that mitophagy can selectively remove dysfunctional mitochondria. Overexpression of ubiquitin-specific protease 30 (USP30) has been documented to in
Autor:
Lunguang Yao, Dandan Li, Juan Xing, Zhongyu Qu, Jiawei Zhou, Qian Xu, Qian Ding, Yugang Guo, Fanghui Bai
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-11 (2021)
Cell Death Discovery
Cell Death Discovery
Ferroptosis is closely linked to various cancers, including lung adenocarcinoma (LUAD); however, the factors involved in the regulation of ferroptosis-related genes are not well established. In this study, we identified and characterized ferroptosis-
Autor:
Pengyun Xie, Shuangnan Zhou, Qiong Xue, Jing Tang, Cuiping Chen, Yupin Liu, Xiaolei Liu, Xuedi Zhang
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-9 (2021)
Cell Death Discovery
Cell Death Discovery
Sepsis is a life-threatening cascading systemic inflammatory response syndrome on account of serve infection. In inflamed tissues, activated macrophages generate large amounts of inflammatory cytokines reactive species, and are exposed to the damagin
Autor:
Jianping Zhang, Tian Zhan, Haojun Yang, Fan Li, Yi Dai, Yuwen Jiao, Yunwei Xia, Liming Tang, Guoguang Wang, Hanyang Liu
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-12 (2021)
Cell Death Discovery
Cell Death Discovery
Platinum drug treatment is one of the most predominant chemotherapeutic strategies for patients with gastric cancer (GC). However, the therapeutic effect is less than satisfactory, largely due to the acquired resistance to platinum drugs. Therefore,
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-11 (2021)
Cell Death Discovery
Cell Death Discovery
Accumulating evidence has suggested that long noncoding RNAs (lncRNAs) exert crucial modulation roles in the biological behaviors of multiple malignancies. Nonetheless, the specific function of lncRNA LINC00284 in papillary thyroid cancer (PTC) remai
Autor:
Philipp Hörmann, Marcel Leist, Karsten Hiller, Jasmin E. Hanke, Sylvie Delcambre, Robert Geffers
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Cell Death Discovery
Cell death discovery 7 (2021) art. 151.-https://doi.org/10.1038/s41420-021-00547-4--Cell Death Discov--http://www.bibliothek.uni-regensburg.de/ezeit/?2842546--https://www.nature.com/cddiscovery/--https://www.ncbi.nlm.nih.gov/pmc/journals/2906/--2058-7716--2058-7716
Cell Death Discovery
Cell death discovery 7 (2021) art. 151.-https://doi.org/10.1038/s41420-021-00547-4--Cell Death Discov--http://www.bibliothek.uni-regensburg.de/ezeit/?2842546--https://www.nature.com/cddiscovery/--https://www.ncbi.nlm.nih.gov/pmc/journals/2906/--2058-7716--2058-7716
L-3,4-Dihydroxyphenylalanin (l-DOPA or levodopa) is currently the most used drug to treat symptoms of Parkinson’s disease (PD). After crossing the blood–brain barrier, it is enzymatically converted to dopamine by neuronal cells and restores deple
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-13 (2021)
Cell Death Discovery
Cell Death Discovery
The mortality rate of ovarian cancer (OC) remains the highest among all gynecological malignancies. Platinum-based chemotherapies are effective in treating most OC cases. However, chemoresistance is still a major challenge for successful OC treatment