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Autor:
Fei Zhang, Lei Wang, Yanglin Yan, Jian Zhang, Tao Wang, Hong Luo, Wuxun Peng, Zhihong Xie, Wentao Dong
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
Novel therapies for the treatment of early steroid-induced osteonecrosis of the femoral head (SONFH) are urgently needed in orthopedics. Transplantation of bone marrow mesenchymal stem cells (BMSCs) provides new strategies for treating this condition
Autor:
Li-Yun Gong, Xing-Xuan Wu, Guan-Zi Chen, Jing Zhu, Li-Yin Liang, Jing-Qiang Huang, Ting Tu, Jun-Wei Song, Chun-Hui Zhou, XingZhi Xu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-16 (2021)
Cell Death & Disease
Cell Death & Disease
Cancer metastasis is the main cause of mortality associated with non-small-cell lung cancer (NSCLC), accounting for up to 70% of deaths among patients. The mechanisms underlying distal metastasis remain largely unknown. Golgi phosphoprotein 3 (GOLPH3
Autor:
Xiangkai Zhang, Shuli Liu, Jiong Deng, Yong Han, Liu Liu, Yang Wang, Shengming Xu, Zhiyuan Zhang, Weimin Ye
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive tumor with poor clinical outcomes due to recurrence, metastasis, and treatment resistance. Cancer stem cells (CSCs), a small population among tumor cells, are proposed to be respons
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
Bladder cancer is one of the most lethal cancers in the world. Despite the continuous development of medical technologies and therapeutic strategies, the overall survival rate of bladder cancer has not changed significantly. Targeted therapy is a new
Autor:
Xiuying Li, Tiao Li, Seyed Mehdi Nouraie, Janet S. Lee, Kong Chen, Georgios D Kitsios, Rama K. Mallampalli, Bryan J. McVerry, Yingze Zhang, Yandong Lai, Chunbin Zou, Toru Nyunoya
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Lung epithelial cell death is a prominent feature of acute lung injury and acute respiratory distress syndrome (ALI/ARDS), which results from severe pulmonary infection leading to respiratory failure. Multiple mechanisms are believed to contribute to
Autor:
Yu Gan, Guoyu Dai, Feng Ru, Zhi Chen, Xiang Chen, Bo Zhang, Yao He, Bingsheng Li, Weiping Xia
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-10 (2021)
Renal fibrosis is a common pathological process that occurs with diverse etiologies in chronic kidney disease. However, its regulatory mechanisms have not yet been fully elucidated. Ferroptosis is a form of non-apoptotic regulated cell death driven b
Autor:
Lu Liu, Kairong Han, Mingyue Tao, Zhengwei Zhang, Zhen Song, Tong Gu, Weiyong Yu, Xiaofei Chen, Xiaojuan Yu, Li Zhang, Xiujuan Huang, Chao Luo, Hao Gu, Jing Luo, Yali Jun, Qilong Wang, Su’an Sun
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-14 (2021)
Tumor cells require high levels of cholesterol for membrane biogenesis for rapid proliferation during development. Beyond the acquired cholesterol from low-density lipoprotein (LDL) taken up from circulation, tumor cells can also biosynthesize choles
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-9 (2021)
Cell Death & Disease
Cell Death & Disease
The lncRNA ZFAS1 plays a carcinogenic regulatory role in many human tumours, but it is rarely reported in pancreatic cancer. We identify the role and molecular mechanisms of ZFAS1 in pancreatic cancer. The expression of ZFAS1, miR-497-5p and HMGA2 in
Autor:
Yan Dai, Jiaming Zhu, Zhihui Lu, Yi Fang, Hong Liu, Jing Chen, Jiachang Hu, Yiran Liang, Jianzhou Zou, Xiaoqiang Ding, Yichun Ning, Nana Song, Jie Teng
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-15 (2021)
Podocytes are known to play a determining role in the progression of proteinuric kidney disease. N6-methyladenosine (m6A), as the most abundant chemical modification in eukaryotic mRNA, has been reported to participate in various pathological process
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-11 (2021)
Axonal degeneration of retinal ganglion cells (RGCs) causes blindness in glaucoma. Currently, there are no therapies that target axons to prevent them from degenerating. Activation of the BAX protein has been shown to be the determining step in the i