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Publikováno v:
Cell Cycle
Circular RNA derived from the SLC8A1 gene (circSLC8A1) has been implicated in the pathogenesis of several types of cancers. However, the role of circSLC8A1 in non-small cell lung cancer (NSCLC) remains unclear. In the present study, the expression le
Publikováno v:
Cell Cycle
CircRNA/miRNA/mRNA axis has been reported to play crucial regulatory roles in multiple cancers, including hepatocellular carcinoma (HCC). In addition, recent investigations revealed that aloin exerted anti-tumor functions in HCC. However, the underly
Autor:
Hua Geng, Saravanan Subramanian, Qiqi Cui, Runxuan Du, Yong Wang, Yuanjie Niu, Chao Wang, Ruibing Chen, Shuang Liu, Dan Yue, Shaoping Tian
Publikováno v:
Cell Cycle
Among urological tumors, renal cell carcinoma (RCC) is the third-highest mortality rate tumor, and 20%–30% of RCC patients present with metastases at the time of diagnosis. While the treatment of RCC has been improved over the last few years, its m
Autor:
Lei Wang, Weike Xie, Chaoxiang Lu, Wang Kai, Shiqi Liu, Qi Wang, Yongkang Pan, Yunhua Wu, Qi Gao
Publikováno v:
Cell Cycle
Gastric cancer (GC) is the most common gastrointestinal malignancy worldwide. However, the molecular mechanisms of the progression of GC are not fully understood. Ras-responsive element binding protein 1 (RREB1) is an oncogene in many types of cancer
Autor:
Zhiwei Zhang, Aixue Zuo, Jihong Shen, Zhengchao Shen, Qingyu Zhang, Xuhua Li, Rong Chen, Enli Cai, Kunbin Ke, Xinan Shi, Hao Fu, Weiping Wan, Rongping Zhang, Jian Wang, Na Song, Xingxing Xie
Publikováno v:
Cell Cycle
Cyclin-dependent kinases (CDKs) are hyperactive in many cancers and have served as cancer therapeutic targets for decades. Palbociclib (Palb) is the first approved CDK4/6 inhibitor to treat hormone receptor (HR)-positive, HER2-negative advanced breas
Publikováno v:
Cell Cycle
Abundant researches have stated that long noncoding RNAs (lncRNAs) are crucial molecules in intricate progression of various cancers in terms of their influence on cell stemness. However, no research has discussed the role of LINC00460 in the stemnes
Autor:
Yanjun Wang, Xinfeng Li, Gaoxiong Wang, Chengzong Li, Xiyin Huang, Tiancong Huang, Juanyong Pan
Publikováno v:
Cell Cycle
Being one of the most prevalent malignancies, hepatocellular carcinoma (HCC) threatens the health of population all over the world. Numerous researches have confirmed that long noncoding RNAs (lncRNAs) play an important role in tumor progression. Non
Publikováno v:
Cell Cycle
Binding sites of the chromatin regulator protein CTCF function as important landmarks in the human genome. The recently characterized CTCF-binding sites at LINE-1 repeats depend on another repeat-regulatory protein CGGBP1. These CGGBP1-dependent CTCF
Publikováno v:
Cell Cycle
Hepatocellular carcinoma (HCC) is a common type of primary liver cancer. Circular RNAs (circRNAs) have been demonstrated to be a crucial player in multiple cancers. However, a large number of circRNAs remain to be explored. Our study focused on inves
Autor:
Mehrdad Ghashghaeinia, Ulrich Mrowietz
Publikováno v:
Cell Cycle
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Enucleated mature human erythrocytes possess NFĸBs and their upstream kinases. There is a negative correlation between eryptosis (cell death of erythrocytes) and the amount of NFĸB subunits p50 and Rel A (p65). This finding is based on the fact tha