Zobrazeno 1 - 10
of 229
pro vyhledávání: ''
Autor:
Luke J Nelson, Kyleen E Castro, Binzhi Xu, Junyi Li, Nguyen B Dinh, Jordan M Thompson, Jordan Woytash, Kevin R Kipp, Olga V Razorenova
Publikováno v:
Cell cycle (Georgetown, Tex.), vol 21, iss 10
Clear cell renal cell carcinoma (CC-RCC) remains one of the most deadly forms of kidney cancer despite recent advancements in targeted therapeutics, including tyrosine kinase and immune checkpoint inhibitors. Unfortunately, these therapies have not b
Autor:
Lei Wang, Weike Xie, Chaoxiang Lu, Wang Kai, Shiqi Liu, Qi Wang, Yongkang Pan, Yunhua Wu, Qi Gao
Publikováno v:
Cell Cycle
Gastric cancer (GC) is the most common gastrointestinal malignancy worldwide. However, the molecular mechanisms of the progression of GC are not fully understood. Ras-responsive element binding protein 1 (RREB1) is an oncogene in many types of cancer
Autor:
Zhiwei Zhang, Aixue Zuo, Jihong Shen, Zhengchao Shen, Qingyu Zhang, Xuhua Li, Rong Chen, Enli Cai, Kunbin Ke, Xinan Shi, Hao Fu, Weiping Wan, Rongping Zhang, Jian Wang, Na Song, Xingxing Xie
Publikováno v:
Cell Cycle
Cyclin-dependent kinases (CDKs) are hyperactive in many cancers and have served as cancer therapeutic targets for decades. Palbociclib (Palb) is the first approved CDK4/6 inhibitor to treat hormone receptor (HR)-positive, HER2-negative advanced breas
Publikováno v:
Cell Cycle
Gastric cancer is one of the most frequently diagnosed malignant tumors, with rapid progression and poor prognosis. The role of chondroitin sulfate synthase 1 (CHSY1) in the development and progression of gastric cancer was explored and clarified in
Autor:
Nadezhda I. Ignatova, Irina N. Druzhkova, Varvara V. Dudenkova, Elena V. Zagaynova, Lyubov’ E. Shimolina, Ludmila B. Snopova, Vsevolod V. Belousov, Marina V. Shirmanova, Maria M. Lukina, Alena I. Gavrina
Publikováno v:
Cell Cycle
Genetically encoded pH-sensors are the promising instrument for intracellular pH (pHi) registration. In tumor tissue the reversed pH gradient is known to be the important hallmark of cancer and regulator of tumor response on chemotherapy. However the
Publikováno v:
Cell Cycle
Evidence has demonstrated that miRNAs play an irreplaceable role in tumorigenesis and progression of a broad range of cancers, including gastric cancer. Among these miRNAs, miR-10a and miR-10b have been identified to critically participate in gastric
Autor:
Shiming Chen, Liping Xie, Yufan Ying, Mingjie Xu, Xiao Wang, Ben Liu, Haixiang Shen, Haiyun Xie, Weiyu Wang, Jiangfeng Li, Liujia He, Xueyou Ma, Xiangyi Zheng
Publikováno v:
Cell Cycle
Emerging research indicates that miRNAs can regulate cancer progression by influencing molecular pathways. Here, we studied miR-665, part of the DLK1-DIO3 miRNA cluster, which is downregulated by upstream methylation in bladder cancer. MiR-665 overex
Publikováno v:
Cell Cycle
The long non-coding RNA HLA complex P5 (HCP5) is extensively related to cancer chemoresistance, while its function in gastric cancer (GC) has not been well elucidated yet. Here, the role and mechanism of HCP5 in regulating the chemoresistance of GC t
Publikováno v:
Cell Cycle
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Accumulating evidence suggests that intrinsic resistance to radiotherapy reduces the survival of patients with cancer. The present study investigated whether miR-93-5p affects proliferation, migration, apoptosis, and radiosensitivity of breast cancer
Publikováno v:
Cell Cycle
It was reported that circular RNA (circRNA) circSMARCA5, as a tumor-related molecule, could modulate development of cancers, including prostatic cancer and cervical cancer. Nevertheless, the essential function of circSMARCA5 in colon cancer has not y