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Autor:
Seung-Youn Jung, Jie-Young Song, Jiyeon Ahn, Dae-Seog Lim, Sang-Gu Hwang, Seon Young Nam, Sungkwan An, Mi-Hyoung Kim, Hee-Jong Woo
Publikováno v:
Cell & Bioscience
Background Radiotherapy is widely used to treat cancer alone or in combination with surgery, chemotherapy, and immunotherapy. However, damage to normal tissues and radioresistance of tumor cells are major obstacles to successful radiotherapy. Further
Autor:
Junchao Cai, Yongbo Huang, Xun Zhu, Huizhong Zhang, Lishan Fang, Mengfeng Li, Caisheng Ye, Jueheng Wu
Publikováno v:
Cell & Bioscience
Background Metastasis-associated in colon cancer-1 (MACC1) was first identified as a transcriptional activator for proto-oncogene c-MET expression, and its overexpression is frequently associated with metastatic progression for multiply tumor types.
Autor:
Sunil Prabhu, Bradley T. Andresen, Moses Ss Chow, Ying Huang, Zhijun Wang, Mandy Liu, Ranadheer Ravula, Arvind Thakkar, Zhong Zuo
Publikováno v:
Cell & Bioscience
Background Induction of Nrf2-mediated detoxifying/antioxidant genes has been recognized as an effective strategy for cancer chemoprevention. Si-Wu-Tang (SWT), comprising the combination of four herbs, Paeoniae, Angelicae, Chuanxiong and Rehmanniae, i
Autor:
Katherine L. Cook, Pamela A.G. Clarke, Robert Clarke, Mones Abu-Asab, David D. Roberts, David R. Soto-Pantoja
Publikováno v:
Cell & Bioscience
Background Autophagy (macroautophagy), a cellular process of “self-eating”, segregates damaged/aged organelles into vesicles, fuses with lysosomes, and enables recycling of the digested materials. The precise origin(s) of the autophagosome membra