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pro vyhledávání: '"556"'
Autor:
Gabriele Matschiner, Corinna Schlosser, Sven Berger, Marlon Hinner, Ulrich Moebius, Christine Rothe, Alexander Wiedenmann, Andrea Allersdorfer, Rachida-Siham Bel Aiba, Shane Olwill
Publikováno v:
Cancer Research. 76:556-556
Background. CD137 (4-1BB) is a key costimulatory immunoreceptor and a member of the TNF-receptor (TNFR) superfamily. While multiple lines of evidence show that CD137 is a highly promising therapeutic target in cancer, current mAb-based approaches are
Autor:
Tvrtko Hudolin, Giulio C. Spagnoli, Maurizio Provenzano, Lukas Bubendorf, Chantal Mengus, Tullio Sulser, Giovanni Sais, Stephen Wyler, Irina Banzola, Hans H. Hirsch
Publikováno v:
Cancer Research. 72:556-556
Background: Polyomavirus BK (BKV) large tumor antigen (L-Tag) contributes to oncogenesis by regulating crucial pathways of human cell cycle when non-permissive cells are infected. Therefore, L-Tag has been identified as an important target of immune
Autor:
Takeshi Hanagiri, Mitsuhiro Takenoyama, Kenji Sugio, Kosei Yasumoto, Makiko Mizukami, Tetsuya So, Masakazu Sugaya, Fukuyama Takashi, Yoshinobu Ichiki, Tomoko So
Publikováno v:
Cancer research. 66(9)
The purpose of our present study is to identify a tumor-specific antigen capable of inducing a specific cellular immune response in lung cancer patients. We established a lung adenocarcinoma cell line, designated as F1121L, and induced tumor-specific