Zobrazeno 1 - 10
of 743
pro vyhledávání: '"35"'
Autor:
Yuan-Qi Zhang, Heng Huang, Anqin Zhang, Ying Lin, Yuhua Song, Zhen Shan, Hongmin Ma, Jianwen Li, Li Cai, Rui Zhuo, Zhiyong Wu, Xiangyang Song, Zhongyu Yuan, Lehong Zhang, Li Zhao, Nan Shao, Ailing Zhang, Jincai Zhong, Herui Yao, Weixiong Yang, Qian-Jun Chen, Kun Wang, Feihai Ling, Hui Liu
Publikováno v:
Cancer Research. 80:OT1-04
In SOFT study, subgroup analysis for hormone receptor-positive (HR+) breast cancer women younger than 35 years indicated better 5-year DFS in OFS+exemestane arm than OFS+tamoxifen. Since only about 11% of women included were younger than 35 years of
Autor:
N Rueth, Karen K. Swenson, M Knaack, Janet Krueger, Barbara Susnik, P Martone, SR Baldinger, Michaela Tsai, Erin Grimm, Tamera J. Lillemoe
Publikováno v:
Cancer Research. 79:P5-10
Background: While breast cancer is rare in women ≤ age 35, patients in this age group are more frequently diagnosed with aggressive cancer subtypes and pathologic germline mutations in cancer susceptibility genes than older patients. Higher recurre
Autor:
Ho Ryun Won, Ji Min Lee, Bok-Soon Lee, Kyung Ah Kim, Haeng-Jun Kim, Chul-Ho Kim, Jae Won Chang, Bon Seok Koo, Hyun-Young Cha, Yeon Soo Kim, Dae Ho Kim
Publikováno v:
Cancer Research. 77:35-35
Background and purpose: It has been reported that the abnormal activation of receptor tyrosine kinases is associated with the development of many human carcinomas and the high activation of EGFR and Met mediates the tumorigenicity of laryngeal carcin
Autor:
Steven Gallinger, Matthew Mistry, Shlomi Constantini, Steve Keiles, Aaron Pollett, Carol Durno, Uri Tabori, Cynthia Hawkins, Derek Stephens, David Malkin, Doua Bakry, Rina Dvir, Eric Bouffet, Shay Ben-Shachar, Ibrahim Qaddoumi, Melyssa Aronson, Qasim Alharbi, Ramyar Lily, Musa Alharbi, Roula Farah, Brittany Campbell, Jordan Lerner-Ellis, Ronit Elhasid
Publikováno v:
Cancer Research. 74:35-35
Purpose: Constitutional mismatch repair deficiency (CMMRD) is a devastating cancer predisposition syndrome affecting children born with two mutated alleles in one of four mismatch repair genes. Data regarding clinical manifestations, molecular screen
Publikováno v:
Cancer Research. 74:35-35
Circulating tumor cells (CTCs) are the tumor cells shed from the primary tumor tissues into the bloodstream or lymphatic vessels. These CTCs are considered to be emerging tools for the detection and prognosis of several types of metastatic cancers. A
Autor:
Jo Anne Zujewski, Jung-Min Lee, John J. Wright, Elise C. Kohn, Nicole D. Houston, Christina M. Annunziata, Anne M. Noonan, Helen X. Chen, John L. Hays, Lori M. Minasian
Publikováno v:
Cancer Research. 73:35-35
Background: Inhibition of the MAPK pathway with sorafenib and neutralization of VEGF with bevacizumab (B) resulted in clinical benefit with interactive toxicity. Dasatinib (D) is a broad spectrum tyrosine kinase inhibitor with high affinity for SRC f
Autor:
M. Babar, T. Boyle, John James Kennedy, L Quinn, B. Dunne, M. Griffin, Elizabeth Connolly, J. Garvin
Publikováno v:
Cancer Research. 69:3043-3043
IntroductionBreast cancer in younger patients is a unique disease entity, associated with aggressive biologic phenotype and poorer prognosis. The aim of this study was to analyse age as a prognostic factor in pre-menopausal breast cancer specifically
Autor:
I. Ospovat, Tamar Peretz, Daniela Katz, L Divinsky, Daliah Galinsky, Tamar Hamburger, Mark Temper, Azzam Salah
Publikováno v:
Cancer Research. 69:6148
Abstract #6148 Background Counseling young breast cancer patients regarding the chances of conception following chemotherapy is a subject of great importance. Previous studies have reported a 50-70% rate of amenorrhea following standard breast cancer
Autor:
J. Balmaña, J. Ferro, S. Gutierrez-Enríquez, M. Masas, N. Gadea, D. Fortuny, C. Saura, O. Díez
Publikováno v:
Cancer Research. 69:4072-4072
Background: Early onset breast cancer is part of the tumor spectrum in the Li-Fraumeni syndrome (MIM 151623), which is associated with germ-line mutations in the TP53 gene. The aim of the study is to determine the presence of inherited mutations in T
Autor:
Michael S. Simon, Yani Lu, Jane Sullivan-Halley, Michael F. Press, Brian L. Strom, Leslie Bernstein, Kathleen E. Malone, Huiyan Ma, Dennis Deapen
Publikováno v:
Cancer Research. 72:3590-3590
Purpose: To evaluate the extent to which the black-white disparity in mortality following breast cancer diagnosis is explained by the expression status of four biomarkers - estrogen receptor (ER), progesterone receptor (PR), human epidermal growth fa