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Autor:
Kana Maruyama, Satomi Kagota, Yukari Tada, Kazumasa Shinozuka, Kazuki Nakamura, Hirokazu Wakuda, Masaru Kunitomo
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 91:124-133
Metabolic syndrome is known to increase the risk of abnormal cardiac structure and function, which are considered to contribute to increased incidence of cardiovascular disease and mortality. We previously demonstrated that ventricular hypertrophy an
Autor:
K SingalPawan, M BhattNiraj, DesaiDipali, ZalawadiaRishit, K SharmaAnita, B PatelVaibhav, BuradeVinod, ChavdaMeenal, GuptaSarita
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 90:1065-1073
We investigated the protective effects of Enicostemma littorale Blume (EL) extract on hypertension and insulin resistance along with its associated cardiovascular complications in high fructose (HF) fed rats. For this, rats were divided among 4 group
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 74:879-886
The JCR:LAncp rat is obese, insulin resistant, and hyperlipidemic, and the males develop atherosclerosis and ischemic myocardial disease. Benfluorex at 35n40 mg·kg n1 body weight was administered in the food from 10 to 14 weeks of age and resulted i
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 71:387-393
Stearate-modified graphite paste electrodes were implanted chronically into dopamine terminal regions in the nucleus accumbens or caudate nucleus of the rat. Reverse dialysis was used to demonstrate a selective response of these electrodes to dopamin
Autor:
Katsuo Kamata, Hiroko Yamaura, Susumu Otomo, Shigeru Okuyama, Yutaka Kasuya, Katsuharu Tsuchida, Noriyuki Miyata
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 71:297-300
The endothelium-dependent relaxation of superior mesenteric arteries of Wistar and genetically diabetic WBN/Kob rats was compared. Endothelium-dependent relaxation induced by acetylcholine (ACh) and A23187 was depressed in WBN/Kob rats. Relaxation in
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 70:695-700
The role of amiloride-dependent sodium channels in the action of adrenal cortical steroids on urine–blood [Formula: see text] (U–B [Formula: see text]) differences was studied in bicarbonate-infused and amiloride-treated adrenalectomized rats. U
Autor:
John S. Elce, Seon H. Shin
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 70:403-407
Dopamine is known to be the prolactin-release inhibiting factor, but the effects of dopamine itself on regulation of prolactin messenger RNA have been little studied because of the instability of dopamine. We have compared the effects of dopamine and
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 70:358-364
We investigated whether cell-to-cell coupling between myometrial cells of parturient rats is influenced by intracellular adenosine 3′,5′-cyclic monophosphate (cAMP) concentration. To evaluate the coupling, we measured input resistance (R0) and in
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 69:1855-1860
Serotonin1A receptor agonists, 8-hydroxy-2-(di-n-propylamino)tetralin and 10-methyl-11-hydroxyaporphine, inhibited electrical stimulation-induced contraction of the guinea-pig ileum. These agonists also inhibited the pressor and tachycardiac response
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 69:1861-1867
Progesterone decreases [1-14C]glucose oxidation in isolated female rat adipocytes within 20 min of incubation. Because steroids regulate transcription mechanisms, the relationship between protein synthesis and glucose metabolism was studied in the pr