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Autor:
Anthonius de Boer, Gerard J.J. Boink, Patrick C. Souverein, Lixia Jia, Hanno L. Tan, Arie O. Verkerk, Marieke T. Blom, Harsha D. Devalla, Talip E Eroglu
Publikováno v:
British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology, 87(9), 3588. NLM (Medline)
British journal of clinical pharmacology, 87(9), 3588-3598. Wiley-Blackwell
British Journal of Clinical Pharmacology, 87(9), 3588-3598. Wiley-Blackwell
Eroglu, T E, Jia, L, Blom, M T, Verkerk, A O, Devalla, H D, Boink, G J J, Souverein, P C, de Boer, A & Tan, H L 2021, ' Sulfonylurea antidiabetics are associated with lower risk of out-of-hospital cardiac arrest : Real-world data from a population-based study ', British Journal of Clinical Pharmacology, vol. 87, no. 9, pp. 3588-3598 . https://doi.org/10.1111/bcp.14774
British Journal of Clinical Pharmacology, 87(9), 3588. NLM (Medline)
British journal of clinical pharmacology, 87(9), 3588-3598. Wiley-Blackwell
British Journal of Clinical Pharmacology, 87(9), 3588-3598. Wiley-Blackwell
Eroglu, T E, Jia, L, Blom, M T, Verkerk, A O, Devalla, H D, Boink, G J J, Souverein, P C, de Boer, A & Tan, H L 2021, ' Sulfonylurea antidiabetics are associated with lower risk of out-of-hospital cardiac arrest : Real-world data from a population-based study ', British Journal of Clinical Pharmacology, vol. 87, no. 9, pp. 3588-3598 . https://doi.org/10.1111/bcp.14774
Aims Out-of-hospital cardiac arrest (OHCA) mostly results from ventricular tachycardia/ventricular fibrillation (VT/VF), often triggered by acute myocardial infarction (AMI). Sulfonylurea (SU) antidiabetics can block myocardial ATP-regulated K+ chann
Autor:
Oscar Della Pasqua, Sean Oosterholt
Publikováno v:
British Journal of Clinical Pharmacology. 87:4718-4725
AIMS Raxibacumab is a fully humanized monoclonal antibody that blocks the interaction of Bacillus anthracis toxins, thereby protecting target cells from its effects. Raxibacumab is approved in the USA for the treatment of adults and children with inh
Publikováno v:
British Journal of Clinical Pharmacology. 88:178-186
AIMS Recent increases in the number of patients with atrial fibrillation (AF) prescribed oral anticoagulants (OAC) are evident in Ireland and internationally, largely due to the availability of direct oral anticoagulants (DOACs). This study aimed to
Publikováno v:
British Journal of Clinical Pharmacology. 88:166-177
Aims The aims of this work were to build a semi-mechanistic tumor growth inhibition (TGI) model for metastatic colorectal cancer (mCRC) patients receiving either cetuximab+chemotherapy or chemotherapy alone and to identify early predictors of overall
Autor:
Rebecca A. Marsh, Junfang Zhao, Kana Mizuno, Parinda A. Mehta, Alexander A. Vinks, Kenneth D.R. Setchell, Stella M. Davies, Sharat Chandra, Tsuyoshi Fukuda
Publikováno v:
British Journal of Clinical Pharmacology. 88:115-127
AIMS We studied melphalan pharmacokinetics (PK) and feasibility of melphalan full-dose adjustment based on test-dose PK in children and young adults with non-malignant disorders (NMD) undergoing allogeneic hematopoietic cell transplantation (HCT) usi
Autor:
Stephen B. Duffull, Tracey L. Putt, Daniel F. B. Wright, Robert J. Walker, Sudeep Pradhan, John B. W. Schollum, Luke C. Wilson, Isabelle H. S. Kuan
Publikováno v:
British Journal of Clinical Pharmacology. 87:4868-4876
This research explored the intact nephron hypothesis (INH) as a model for metformin dosing in patients with chronic kidney disease (CKD). The INH assumes that glomerular filtration rate (GFR) will account for all kidney drug handling even for drugs e
Autor:
Kirsti Tiihonen, Arthur C. Ouwehand, Mika Scheinin, Marita Kailajärvi, Sanna M. Mäkelä, Sofia D. Forssten, Ville L. Langen
Publikováno v:
British Journal of Clinical Pharmacology. 87:4625-4635
AIMS Use of nonsteroidal anti-inflammatory drugs (NSAIDs) can cause damage to the gastric and duodenal mucosa. Some probiotics have proven useful in ameliorating the harmful side-effects of NSAIDs. Our aim was to evaluate whether oral administration
Autor:
Frederico Bartolazzi, Marcus Fernando da Silva Praxedes, Maria Auxiliadora Parreiras Martins, Mayara Sousa Vianna, José Luiz Padilha da Silva, Catiane Costa Viana, Waleska Jaclyn Freitas Nunes de Sousa
Publikováno v:
British Journal of Clinical Pharmacology. 87:4488-4503
Aim We sought to investigate the association between sex and oral anticoagulation control employing coumarin derivatives. Methods Electronic sources were MEDLINE, Biblioteca Virtual em Saude (BVS), The Cumulative Index to Nursing and Allied Health Li
Autor:
Han Yan, Hoan Linh Banh, Huan-De Li, Ping Xu, Feng Wang, Yangang Zhou, Bikui Zhang, Wu Liang, Da-Xiong Xiang
Publikováno v:
British Journal of Clinical Pharmacology. 87:2838-2846
BACKGROUND Tigecycline has been widely used to treat hospital-acquired pneumonia (HAP) off-label since it is effective against a wide range of multidrug-resistant bacteria. However, no recommended dosage for this indication has been evaluated, result
Autor:
Hee Jae Choi, Barry E. Bleske, Xinwen Wang, Hao Jie Zhu, Jian Shi, Lucy Her, Logan S. Smith, Sun Min Jung, Audrey H. Wu
Publikováno v:
British Journal of Clinical Pharmacology. 87:4691-4700
AIMS Enalapril is a prodrug and needs to be activated by carboxylesterase 1 (CES1). A previous in vitro study demonstrated the CES1 genetic variant, G143E (rs71647871), significantly impaired enalapril activation. Two previous clinical studies examin