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Autor:
Kirsti Tiihonen, Arthur C. Ouwehand, Mika Scheinin, Marita Kailajärvi, Sanna M. Mäkelä, Sofia D. Forssten, Ville L. Langen
Publikováno v:
British Journal of Clinical Pharmacology. 87:4625-4635
AIMS Use of nonsteroidal anti-inflammatory drugs (NSAIDs) can cause damage to the gastric and duodenal mucosa. Some probiotics have proven useful in ameliorating the harmful side-effects of NSAIDs. Our aim was to evaluate whether oral administration
Autor:
Frederico Bartolazzi, Marcus Fernando da Silva Praxedes, Maria Auxiliadora Parreiras Martins, Mayara Sousa Vianna, José Luiz Padilha da Silva, Catiane Costa Viana, Waleska Jaclyn Freitas Nunes de Sousa
Publikováno v:
British Journal of Clinical Pharmacology. 87:4488-4503
Aim We sought to investigate the association between sex and oral anticoagulation control employing coumarin derivatives. Methods Electronic sources were MEDLINE, Biblioteca Virtual em Saude (BVS), The Cumulative Index to Nursing and Allied Health Li
Autor:
Klaus G. Parhofer, Anja Kerksiek, Bediha Bölükbasi, Ulrich Laufs, Dieter Lütjohann, Frans Stellaard
Publikováno v:
British Journal of Clinical Pharmacology. 87:4252-4261
AIMS The serum ratios of the brain-specific oxysterol 24S-hydroxycholesterol (24S-OHC) to cholesterol and to 27-OHC reflect brain cholesterol turnover. We studied the effect of proprotein convertase subtilisin/kexin type 9 monoclonal antibodies (PCSK
Autor:
Jean-Louis Montastruc, Geneviève Durrieu, François Montastruc, Agnès Sommet, Haleh Bagheri, Claire de Canecaude, Margaux Lafaurie
Publikováno v:
British Journal of Clinical Pharmacology. 87:4334-4340
Aims Adverse drug reactions (ADRs) are important causes of death. However, the main involved drugs are relatively unknown. The present study was performed to characterise death-related drugs recorded in a large pharmacovigilance database during the l
Autor:
Soo Hyun Seo, Jae Yong Chung, Kyoung Un Park, Jae Ho Lee, Seonghae Yoon, Jongsun Park, Junghan Song, Eun Sun Kim, Byoung Soo Kwon
Publikováno v:
British Journal of Clinical Pharmacology. 87:3492-3500
Aims Rifampicin is a key drug for the treatment of tuberculosis (TB). Little is known for the relationship between the rifampicin pharmacokinetics and genetic polymorphisms in the Asian population. We aimed to investigate relationship between genetic
Autor:
Mei Zhang, Bo Ban, Bin Du, Xiao-Fu Cao, Xue Li, Fan Yang, Yanhong Zhang, Yuan Xu, Xi-Ting Liu, Qiu-Ping Zhang, Yue Zhou, Zhuo-Xiang Sun, Wei Zhao, Qianqian Zhao, Min Kan
Publikováno v:
British Journal of Clinical Pharmacology. 87:3599-3607
Objective Recently, letrozole has been used off-label in short pubertal boys. The experience on letrozole effectiveness and safety has been primary obtained from Caucasian children. A simple extrapolation of the data to Chinese pediatric populations
Autor:
Oscar Della Pasqua, Matthias Oelke, Chandrashekhar Chavan, Martin C. Michel, Michael J. Manyak, Claus G. Roehrborn, Juan Manuel Palacios-Moreno, Salvatore D'Agate
Publikováno v:
British Journal of Clinical Pharmacology
Aims Combination therapy of 5α‐reductase inhibitor and α‐blocker is a guideline‐endorsed therapeutic approach for patients with moderate‐to‐severe lower urinary tract symptoms or benign prostatic hyperplasia (LUTS/BPH) who are at risk of
Autor:
William Novotny, Zhiyu Tang, Srikumar Sahasranaman, Ying C. Ou, Ta-Kai Li, Hugh A Coleman, Manal Tawashi
Publikováno v:
British Journal of Clinical Pharmacology
Aim This study aims to assess the potential effects of zanubrutinib on the activity of cytochrome P450 (CYP) enzymes and drug transporter proteins using a cocktail probe approach. Methods Patients received single oral doses of probe drugs alone and a
Publikováno v:
British journal of clinical pharmacology, 87(4):1778-1789
AIM:To estimate the extent of off-label prescribing of antidepressants in older adults and to characterize patients with off-label vs on-label prescriptions of antidepressants using a large German health claims database. METHODS:Using data from the G
Autor:
Israa Al-Shekh, Abdul Rahman Arabi, Fadi Khir, Ahmed Mahfouz, Alaa Rahhal, Amer Aljundi, Sumaya Alyafei, Masa Habra, Yaser Alahmad, Ahmed Awaisu, Hakam Alzaeem
Publikováno v:
British Journal of Clinical Pharmacology. 87:2043-2052
Aims: To compare the effectiveness and safety of 2 high-intensity atorvastatin doses (40 mg vs 80 mg) among acute coronary syndrome (ACS) patients. Methods: This retrospective observational cohort study using real-world data included patients admitte