Zobrazeno 1 - 10
of 141
pro vyhledávání: ''
Publikováno v:
Brain Research. 1426:18-29
Applying emetine, a protein synthesis inhibitor, at 20–40 μM for 90–120 min prior to LTP induction in hippocampal slices from young rats (2–3 weeks) and washing it out afterwards revealed a slowly developing potentiation that reached maximum a
Autor:
Hans-Günther Knaus, Luis F. Pacheco Otalora, Ileana Garcia, Frank Skinner, Carlos Fernando Mello, Boris Ermolinsky, Emilio R. Garrido-Sanabria, Massoud F. Arshadmansab, Mauro Schneider Oliveira
Publikováno v:
Brain Research. 1348:187-199
Small conductance calcium (Ca(2+)) activated SK channels are critical regulators of neuronal excitability in hippocampus. Accordingly, these channels are thought to play a key role in controlling neuronal activity in acute models of epilepsy. In this
Publikováno v:
Brain Research. 1183:60-65
Background: In rat hippocampal slices, a short hypoxia/hypoglycemia causes immediate loss of evoked potentials (population spike amplitude) in the CA1 region and the extent of electrophysiological restoration during reperfusion can serve as a paramet
Autor:
Richard W. Olsen, Neil L. Harrison, Gregg E. Homanics, David F. Werner, Frank P. Elsen, Patricia Liljelund
Publikováno v:
Brain Research. 1078:60-70
Gamma-aminobutyric acid-type A receptors (GABA(A)-Rs) have been proposed as a target for many general anesthetics. We recently created knockin (KI) mice harboring a point mutation (serine 270 to histidine) in the GABA(A)-R alpha1 subunit. This mutati
Publikováno v:
Brain Research. 1046:116-121
Electroneutral cation-chloride cotransporters are abundantly expressed in the brain and are involved in the regulation of the intracellular Cl(-) concentration and thus gamma-aminobutyric acid-dependent inhibition of neuronal excitability. As yet the
Autor:
Katsuhiro Konno, Gianina Teribele Venturin, Ken-ichi Nihei, Fernanda de Borba Cunha, Mario Sergio Palma, Raquel Mattos de Oliveira, Simone Denise Salamoni, Daniela Souza de Abreu, Jaderson Costa da Costa, Andrea Luisa Alencar Tavares, Ricardo Vaz Breda
Publikováno v:
Brain Research. 1048:170-176
The Joro spider toxin (JSTX-3), derived from Nephila clavata, has been found to block glutamate excitatory activity. Epilepsy has been studied in vitro, mostly on rat hippocampus, through brain slices techniques. The aim of this study is to verify th
Publikováno v:
Brain Research. 1019:270-274
The role of gap junction coupling in generation of carbachol-induced theta-like activity (TLA) in hippocampal formation (HPC) slices was investigated in this study. Two gap junction (GJ) blockers, carbenoxolone (100 microM) and quinine (100 microM),
Publikováno v:
Brain Research. 1021:76-81
In the present study we tested the ability of the inhalation anesthetic sevoflurane to induce preconditioning against hypoxia in vitro. Rat hippocampal slices were prepared using established procedures. After 90 min of incubation, slices were exposed
Publikováno v:
Brain Research. 1017:92-97
Neuroprotective action of MK-801 administrated pre- and postischemically, in vivo or in vitro, respectively, was studied on hippocampal slices using decapitation ischemia model. Recovery of orthodromic population spikes in CA1 region was measured dur
Publikováno v:
Brain Research. 1003:176-182
To examine regional differences of synaptic transmission, the effects of midazolam were observed on inhibitory postsynaptic currents (IPSCs) in CA1 pyramidal cells (CA1-PCs) and dentate gyrus granule cells (DG-GCs) in rat hippocampal slices. Midazola