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Publikováno v:
Brain Research. 1624:78-85
3-O-demethylswertipunicoside (3-ODS) has been reported to protect dopaminergic neurons against neurotoxicity induced by 1-methyl-4-phenylpyridinium (MPP(+)) in PC12 cells. Here, we investigate the neuroprotective effects in vivo and antioxidant activ
Publikováno v:
Brain Research. 1554:12-20
Extracellular acidosis is a common feature in pain-generating pathological conditions. Acid-sensing ion channels (ASICs), pH sensors, are distributed in peripheral sensory neurons and participate in nociception. Morphine exerts potent analgesic effec
Autor:
V. Visockis, Anne King
Publikováno v:
Brain Research. 1513:9-16
There is strong evidence that M-currents modulate peripheral sensory afferent excitability and that altered M-current efficacy may underpin aspects of pain-induced nociceptor sensitization. Less clear is the role of the M-current in regulating centra
Publikováno v:
Brain Research. 1426:18-29
Applying emetine, a protein synthesis inhibitor, at 20–40 μM for 90–120 min prior to LTP induction in hippocampal slices from young rats (2–3 weeks) and washing it out afterwards revealed a slowly developing potentiation that reached maximum a
Publikováno v:
Brain Research. 1349:48-55
Studies have demonstrated defects of DA and 5HT neurotransmission in dietary fat induced obese animals. In the present study, we used a perfusion system to assay the release of DA and 5HT from striatal slices preloaded with [(3)H]-DA or [(3)H]-5HT. T
Publikováno v:
Brain Research. 1317:80-86
Descending noradrenergic inhibition is an important endogenous pain-relief mechanism which can be activated by local glutamate signaling. In the present study, we examined the effect of glutamate transporter activation by riluzole in the regulation o
Publikováno v:
Brain Research. 1248:184-190
In traditional medicine, Panax ginseng has been used to treat various behavioral effects of psychostimulants (e.g., cocaine) and other drugs of abuse and to ameliorate withdrawal symptoms. The neurochemical bases for this efficacy, however, remain to
Publikováno v:
Brain Research. 1168:32-37
Glycine is known as an inhibitory neurotransmitter in the spinal cord and forebrain but its precise role in the forebrain is largely overlooked. This investigation evaluated whether glycine alters acetylcholine, glutamate or dopamine release from str
Publikováno v:
BRAIN RESEARCH
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
We investigate possible interactions between acetylcholine (ACh)- and adenosine 5′-triphosphate (ATP)-induced responses of petrosal ganglion, where the perikarya of most sensory neurons of the glossopharyngeal nerve are located. Experiments were pe
Autor:
Jun Yamada, Mami Noda, Kei Eto, Yukiko Arimura, Hitoshi Ishibashi, Yoshiko Hatano, Masazumi Nishikawa, Kazuo Takahama
Publikováno v:
Brain Research. 1097:65-70
Dextromethorphan is one of the most widely used antitussives for the treatment of cough. In the present study, we investigated the effect of dextromethorphan on 5-hydroxytryptamine (5-HT)-induced currents in acutely dissociated rat nodose ganglion ne