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Autor:
Benjamin M Jacobs, Luisa Schalk, Angie Dunne, Antonio Scalfari, Ashwini Nandoskar, Bruno Gran, Charles A Mein, Charlotte Sellers, Cord Spilker, David Rog, Elisa Visentin, Elizabeth Lindsey Bezzina, Emeka Uzochukwu, Emma Tallantyre, Eva Wozniak, Eve Sacre, Ghaniah Hassan-Smith, Helen L Ford, Jade Harris, Joan Bradley, Joshua Breedon, Judith Brooke, Karim L Kreft, Katherine Tuite Dalton, Katila George, Maria Papachatzaki, Martin O'Malley, Michelle Peter, Miriam Mattoscio, Neisha Rhule, Nikos Evangelou, Nimisha Vinod, Outi Quinn, Ramya Shamji, Rashmi Kaimal, Rebecca Boulton, Riffat Tanveer, Rod Middleton, Roxanne Murray, Ruth Bellfield, Sadid Hoque, Shakeelah Patel, Sonia Raj, Stephanie Gumus, Stephanie Mitchell, Stephen Sawcer, Tarunya Arun, Tatiana Pogreban, Terri-Louise Brown, Thamanna Begum, Veronica Antoine, Waqar Rashid, Alastair J Noyce, Eli Silber, Huw Morris, Gavin Giovannoni, Ruth Dobson
Publikováno v:
BMJ Open. 13:e071656
PurposeGenetic studies of multiple sclerosis (MS) susceptibility and severity have focused on populations of European ancestry. Studying MS genetics in other ancestral groups is necessary to determine the generalisability of these findings. The genet
Autor:
Tom Parks, Litia Narube, Mai Ling Perman, Kelera Sakumeni, James J Fong, Daniel Engelman, Samantha M Colquhoun, Andrew C Steer, Joseph Kado
Publikováno v:
BMJ Open. 13:e070629
ObjectiveTo determine population-based rates of non-fatal complications of rheumatic heart disease (RHD).DesignRetrospective cohort study based on multiple sources of routine clinical and administrative data amalgamated by probabilistic record-linkag
Autor:
Wonder P Drake, Connie Hsia, Lobelia Samavati, Michelle Yu, Jessica Cardenas, Fabiola G Gianella, John Boscardin, Laura L Koth
Publikováno v:
BMJ open, vol 13, iss 4
IntroductionSarcoidosis is a pulmonary and systemic granulomatous disease with a wide range of potential outcomes, from spontaneous resolution to end-stage organ damage and death. Currently, clinicians have no easy-to-use risk stratification tools fo
Autor:
Maria E Bleil, Glenn I Roisman, Steven E Gregorich, Bradley M Appelhans, Robert A Hiatt, Robert C Pianta, Anna L Marsland, George M Slavich, Alexis S Thomas, Winnie S Yeung, Cathryn Booth-LaForce
Publikováno v:
BMJ open, vol 13, iss 3
PurposeThe purpose of the current study, The National Institute of Child Health and Human Development (NICHD) Study of Health in Early and Adult Life (SHINE), was to build on the landmark Study of Early Child Care and Youth Development (SECCYD), a lo
Autor:
Samuel Hall, Jacqueline Birks, Ian Anderson, Andrew Bacon, Paul M Brennan, David Bennett, Emmanuel Chavredakis, Giles Critchley, Graham Dow, Jonathan Downer, James Galea, Patrick Grover, Nihal Gurusinghe, Adel Helmy, Gueorgui Kounin, Nitin Mukerji, Hiren Patel, Jash Patel, Nicholas Ross, Jerome St George, Mario Teo, Christos Michael Tolias, Nikolaos Tzerakis, Christopher Uff, Janneke van Beijum, Kristin Veighey, Edward White, Peter Whitfield, Diederik Oliver Bulters
Publikováno v:
Hall, S, Birks, J, Anderson, I, Bacon, A, Brennan, P M, Bennett, D, Chavredakis, E, Critchley, G, Dow, G, Downer, J, Galea, J, Grover, P, Gurusinghe, N, Helmy, A, Kounin, G, Mukerji, N, Patel, H, Patel, J, Ross, N, St George, J, Teo, M, Tolias, C M, Tzerakis, N, Uff, C, van Beijum, J, Veighey, K, White, E & Whitfield, P & Bulters, D O 2023, ' Risk of Aneurysm Rupture (ROAR) study : protocol for a long-term, longitudinal, UK multicentre study of unruptured intracranial aneurysms ', BMJ Open, vol. 13, no. 3, pp. e070504 . https://doi.org/10.1136/bmjopen-2022-070504
IntroductionUnruptured intracranial aneurysms (UIA) are common in the adult population, but only a relatively small proportion will rupture. It is therefore essential to have accurate estimates of rupture risk to target treatment towards those who st
Publikováno v:
BMJ Open. 12(5)
ObjectivesAlthough several individual risk factors of frequent outpatient attendance (FOA) have previously been reported, identifying a specific risk profile is needed to provide effective intervention for impoverished citizens with complex biopsycho
Autor:
Lee, Sian Ing, Hope, Holly, O'Reilly, Dermot, Kent, Lisa, Santorelli, Gillian, Subramanian, Anuradhaa, Moss, Ngawai, Azcoaga-Lorenzo, Amaya, Fagbamigbe, Adeniyi, Nelson-Piercy, Catherine, Yau, Christopher, McCowan, Colin, Kennedy, Jonathan I, Phillips, Katherine, Singh, Megha, Mhereeg, Mohamed, Cockburn, Neil, Brocklehurst, Peter, Plachcinski, Rachel, Riley, Richard, Thangaratinam, Shakila, Brophy, Sinead, Sudasinghe, Sudasing Pathirannehelage Buddhika Hemali, Agrawal, Utkarsh, Vowles, Zoe, Abel, Kathryn M, Nirantharakumar, Krishnarajah, Black, Mairead, Eastwood, Kelly-Ann, MuM-PreDiCT Group
Publikováno v:
Hope, H, Abel, K & et al. 2023, ' Maternal and child outcomes for pregnant women with pre-existing multiple long-term conditions: protocol for an observational study in the UK ', BMJ Open, vol. 13, no. 2, e068718 . https://doi.org/10.1136/bmjopen-2022-068718
MuM-PreDiCT, Lee, S I, Hope, H, O'Reilly, D, Kent, L, Santorelli, G, Subramanian, A, Moss, N, Azcoaga-Lorenzo, A, Fagbamigbe, A F, Nelson-Piercy, C, Yau, C, McCowan, C, Kennedy, J I, Phillips, K, Singh, M, Mhereeg, M, Cockburn, N, Brocklehurst, P, Plachcinski, R, Riley, R D, Thangaratinam, S, Brophy, S, Hemali Sudasinghe, S P B, Agrawal, U, Vowles, Z, Abel, K M, Nirantharakumar, K, Black, M & Eastwood, K-A 2023, ' Maternal and child outcomes for pregnant women with pre-existing multiple long-term conditions: protocol for an observational study in the UK ', BMJ Open, vol. 13, no. 2, e068718 . https://doi.org/10.1136/bmjopen-2022-068718
MuM-PreDiCT, Lee, S I, Hope, H, O'Reilly, D, Kent, L, Santorelli, G, Subramanian, A, Moss, N, Azcoaga-Lorenzo, A, Fagbamigbe, A F, Nelson-Piercy, C, Yau, C, McCowan, C, Kennedy, J I, Phillips, K, Singh, M, Mhereeg, M, Cockburn, N, Brocklehurst, P, Plachcinski, R, Riley, R D, Thangaratinam, S, Brophy, S, Hemali Sudasinghe, S P B, Agrawal, U, Vowles, Z, Abel, K M, Nirantharakumar, K, Black, M & Eastwood, K-A 2023, ' Maternal and child outcomes for pregnant women with pre-existing multiple long-term conditions: protocol for an observational study in the UK ', BMJ Open, vol. 13, no. 2, e068718 . https://doi.org/10.1136/bmjopen-2022-068718
Funding: This work is funded by the Strategic Priority Fund 'Tackling multimorbidity at scale' programme (grant number MR/W014432/1) delivered by the Medical Research Council and the National Institute for Health Research (NIHR) in partnership with t
Autor:
Yvonne Zurynski, Louise A Ellis, Chiara Pomare, Isabelle Meulenbroeks, James Gillespie, Jo Root, James Ansell, Joanna Holt, Leanne Wells, Jeffrey Braithwaite
Publikováno v:
BMJ Open. 12:e061623
ObjectivesWith the rate of chronic conditions increasing globally, it is important to understand whether people with chronic conditions have the capacity to find the right care and to effectively engage with healthcare providers to optimise health ou
Autor:
Lidor Peretz, Akiva Grossman, Salih J Saeed, Talia Appleboim-Refael, Yair Zloof, Limor Friedensohn, Shachar Shapira, Amir Shlaifer, Itamar Grotto
Publikováno v:
BMJ Open. 12:e066094
ObjectivesTo determine the association of symptomatic and asymptomatic mild COVID-19 and the SARS-CoV-2 viral load with the physical fitness of army cadets.DesignA retrospective case–control study.SettingOfficers’ Training School of the Israel De
Prevalence of long COVID-19 among healthcare workers: a systematic review and meta-analysis protocol
Autor:
Amani Al-Oraibi, Jatin Sridhar Naidu, Aasiya Chaka, Katherine Woolf, Laura B Nellums, Carolyn Tarrant, Daniel Pan, Shirley Sze, Christopher A Martin, Mayuri Gogoi, Joshua Nazareth, Manish Pareek
Publikováno v:
BMJ Open. 12:e065234
IntroductionA proportion of those who survive the acute phase of COVID-19 experience prolonged symptoms, commonly known as long COVID-19. Given that healthcare workers (HCWs) face an elevated risk of acute COVID-19 compared with the general populatio