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Autor:
Chiara Giacomelli, Astrid Wachter, Stefan Wiemann, Jung J, Yosef Yarden, Cindy Körner, Ozgur Sahin, Stefan Uhlmann, Rainer Will, Ulrike Korf, Ibing S, Tim Beißbarth, Heiko Mannsperger
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-19 (2021)
BMC Cancer
BMC Cancer
Background Triple negative breast cancer (TNBC) is the most aggressive subtype of breast cancer (BC). Treatment options for TNBC patients are limited and further insights into disease aetiology are needed to develop better therapeutic approaches. mic
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)
BMC Cancer
BMC Cancer
Background Malignant pleural mesothelioma (MPM) is a rare but fatal cancer, which is largely caused by exposure to asbestos. Reliable information about the incidence of MPM prior the influence of asbestos is lacking. The nationwide regional incidence
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-14 (2021)
BMC Cancer
BMC Cancer
Background We have proposed a modified, completely intrafascial radical cysprostatectomy (RC) to treat bladder cancer patients with the aim of preserving the patients’ post-surgical urinary control and erectile function. This study aimed to evaluat
Autor:
Akihisa Kamataki, Naoya Suzuki, Kosuke Katayama, Kenichiro Asano, Akira Kurose, Hiroki Ohkuma, Toshio Fumoto, Seiko Hasegawa, Masashi Matsuzaka, Kenichi Akasaka
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)
BMC Cancer
BMC Cancer
Background This investigator-initiated, open-label, single-arm, single-institute study was conducted to investigate the effectiveness of induction combination chemoradiotherapy and long-term maintenance therapy with temozolomide (TMZ) plus interferon
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)
BMC Cancer
BMC Cancer
Background MCM3AP-AS1 is a recently characterized lncRNA playing an oncogenic role in several cancers. However, its role in lung cancer remains unknown. Here, we aimed to explore the functions of MCM3AP-AS1 in small cell lung cancer (SCLC) and the po
Autor:
Nelly Firmin, C. Touraine, Véronique D'Hondt, L. Roca, S Pouderoux, Hélène de Forges, Lobna Rifai, Séverine Guiu, Marie Viala, William Jacot, Gilles Romieu, Manon Metge
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Cancer
BMC Cancer, BioMed Central, 2021, 21 (1), pp.815. ⟨10.1186/s12885-021-08563-4⟩
BMC Cancer
BMC Cancer, BioMed Central, 2021, 21 (1), pp.815. ⟨10.1186/s12885-021-08563-4⟩
Background Changes in calcium metabolism and calcium urinary excretion during chemotherapy have not been thoroughly assessed in patients with early breast cancer (EBC), a population who frequently present vitamin D insufficiency. As hypercalciuria is
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
BMC Cancer
BMC Cancer
Background Tumor mutation burden (TMB) is an emerging prognostic biomarker of immunotherapy for bladder cancer (BLCA). We aim at investigating radiomic features’ value in predicting the TMB status of BLCA patients. Methods Totally, 75 patients with
Autor:
Brian Seal, Candice Yong, Trudy Buckingham, Anna Hung, Kyung Min Lee, Michael J. Kelley, Bradley J. Hintze, Yanhong Li, Shelby D. Reed, Julie Lynch, Olga V. Efimova, Pradeep J. Poonnen
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Cancer
BMC Cancer
BackgroundThe Veterans Health Administration (VHA) is the largest integrated health care system in the United States (US). Among VHA patients, the rate of use of concurrent chemoradiation therapy (CCRT) among those with unresectable, stage III non-sm
Autor:
Xin-Yuan Wang, Qing-Wei Zhang, Jialin Meng, Jin-Nan Chen, Fangrong Yan, Xiaofan Lu, Yu-Jie Zhou, Xiaobo Li, Qi-Wen Wang
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
BMC Cancer
BMC Cancer
Background Due to negative results in clinical trials of postoperative chemoradiation for gastric cancer, at present, there is a tendency to move chemoradiation therapy forward in gastric and gastroesophageal junction (GEJ) adenocarcinoma. Several ra
Autor:
Semi Harrabi, Meinhard Kieser, Sebastian Adeberg, Kristin Lang, Jürgen Debus, Klaus Herfarth, Thomas Held
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)
BMC Cancer
BMC Cancer
Background Adenoid cystic carcinoma is a rare form of head and neck cancer with a slow, but aggressive growth pattern which remains a challenge for local tumor control. Based on phase II data, radiation treatment using partially high LET radiation re