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Publikováno v:
Blood Cancer Journal, Vol 11, Iss 6, Pp 1-9 (2021)
Blood Cancer Journal
Blood Cancer Journal
In 1957, Hillestad et al. defined acute promyelocytic leukemia (APL) for the first time in the literature as a distinct type of acute myeloid leukemia (AML) with a “rapid downhill course” characterized with a severe bleeding tendency. APL, accoun
Autor:
Mrinal M. Patnaik, Rong He, David S. Viswanatha, Dragan Jevremovic, William J. Hogan, Zhuoer Xie, Hassan B. Alkhateeb, Aref Al-Kali, Naseema Gangat, Mohamad E. Salama, Ayalew Tefferi, Kurt R Bessonen, Mark R. Litzow, Mithun Vinod Shah, Ahmad Nanaa, Phuong L. Nguyen, Patricia T. Greipp, Animesh Pardanani
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 6, Pp 1-4 (2021)
Blood Cancer Journal
Blood Cancer Journal
Autor:
Florent Malard, Jean-Luc Harousseau, Ali Bazarbachi, Abdul Hamid Bazarbachi, Mohamad Mohty, Rama Al Hamed
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 5, Pp 1-13 (2021)
Blood Cancer Journal
Blood Cancer Journal, 2021, 11 (5), pp.97. ⟨10.1038/s41408-021-00486-4⟩
Blood Cancer Journal, Nature Publishing Group, 2021, 11 (5), pp.97. ⟨10.1038/s41408-021-00486-4⟩
Blood Cancer Journal
Blood Cancer Journal, 2021, 11 (5), pp.97. ⟨10.1038/s41408-021-00486-4⟩
Blood Cancer Journal, Nature Publishing Group, 2021, 11 (5), pp.97. ⟨10.1038/s41408-021-00486-4⟩
Amyloid light chain (AL) amyloidosis is among the more common and more severe of the amyloidoses usually involving the slow proliferation of a bone-marrow-residing plasma cell (PC) clone and the secretion of unstable immunoglobulin-free light chains
Autor:
Maria Gavriatopoulou, Lia-Angela Moulopoulos, Evangelos Terpos, Nikolaos Kanellias, Andriani Βoultadaki, Efstathios Kastritis, Panagiotis Malandrakis, Ioannis Ntanasis-Stathopoulos, Magdalini Migkou, Charis Bourgioti, Despina Fotiou, Meletios A. Dimopoulos, Evangelos Eleutherakis-Papaiakovou, Vassilis Koutoulidis
Publikováno v:
Blood Cancer Journal, Vol 10, Iss 9, Pp 1-7 (2020)
Blood Cancer Journal
Blood Cancer Journal
Introduction: Multiple myeloma (MM) is the second most common haematological malignancy and is characterized by bone marrow infiltration of monoclonal plasma cells and end-organ involvement. Smoldering MM (SMM) is an intermediate clinical entity betw
Autor:
Miguel-Angel Perales, Elena Mead, Sean M. Devlin, Aishat Afuye, Kitsada Wudhikarn, M. Lia Palomba, Michael Scordo, Martina Pennisi, Mari Lynne Silverberg, Marta Garcia-Recio, Molly Maloy, Connie L Batlevi, Gunjan L. Shah, Bianca Santomasso, Parastoo B. Dahi, Jessica Flynn, Craig S. Sauter, Susan K. Seo
Publikováno v:
Blood Cancer Journal, Vol 10, Iss 8, Pp 1-11 (2020)
Blood Cancer Journal
Blood Cancer Journal
CD19-targeted chimeric antigen receptor (CAR) T cell therapy is an effective treatment for diffuse large B cell lymphoma (DLBCL). In addition to cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity (ICANS), B cell aplasia
Autor:
Bradley Heidrich, Yingzhe Li, Leopoldo Luistro, Mcdaid Ronan, Priyanka Nair-Gupta, Kathryn Packman, Francois Gaudet, Stephen I. Rudnick, Jocelin Joseph, Melissa Smith, Ricardo Attar, Kodandaram Pillarisetti
Publikováno v:
Blood Cancer Journal, Vol 10, Iss 6, Pp 1-13 (2020)
Blood Cancer Journal
Blood Cancer Journal
Redirecting T cells to specifically kill malignant cells has been validated as an effective anti-cancer strategy in the clinic with the approval of blinatumomab for acute lymphoblastic leukemia. However, the immunosuppressive nature of the tumor micr
Autor:
Naval Daver, Courtney D. DiNardo, Ahmad Ghorab, Farhad Ravandi, Allyson Price, Tapan M. Kadia, Naveen Pemmaraju, Gautam Borthakur, Xuemei Wang, Dai Chihara, Fevzi Firat Yalniz, Koji Sasaki, Hagop M. Kantarjian, Keyur P. Patel, Ghayas C. Issa, Jorge E. Cortes, Hyunsoo Hwang, Iman Abou Dalle
Publikováno v:
Blood Cancer Journal, Vol 10, Iss 5, Pp 1-10 (2020)
Blood Cancer Journal
Blood Cancer Journal
FLT3-ITD mutations in newly diagnosed acute myeloid leukemia (AML) are associated with worse overall survival (OS). FLT3-ITD diversity can further influence clinical outcomes. Addition of FLT3 inhibitors to standard chemotherapy has improved OS. The
Autor:
Hayley Suen, Gabriele De Rubis, Yiu Lam Kwan, Douglas E. Joshua, Sabna Rajeev Krishnan, Mary Bebawy
Publikováno v:
Blood Cancer Journal, Vol 10, Iss 3, Pp 1-11 (2020)
Blood Cancer Journal
Blood Cancer Journal
Multiple myeloma is an incurable cancer of bone marrow plasma cells, with a 5-year survival rate of 43%. Its incidence has increased by 126% since 1990. Treatment typically involves high-dose combination chemotherapy, but therapeutic response and pat
Autor:
Daiichiro Hasegawa, Toshihiko Imamura, Keiko Yumura-Yagi, Yoshihiro Takahashi, Ikuya Usami, So-ichi Suenobu, Shinichiro Nishimura, Nobuhiro Suzuki, Yoshiko Hashii, Takao Deguchi, Akiko Moriya-Saito, Koji Kato, Yoshiyuki Kosaka, Masahiro Hirayama, Akihiro Iguchi, Hirohide Kawasaki, Hiroki Hori, Atsushi Sato, Tooru Kudoh, Tatsutoshi Nakahata, Megumi Oda, Junichi Hara, Keizo Horibe, for the Japan Association of Childhood Leukemia Study Group (JACLS)
Publikováno v:
Blood Cancer Journal, Vol 10, Iss 2, Pp 1-11 (2020)
Blood Cancer Journal
Blood Cancer Journal
This study was a second multicenter trial on childhood ALL by the Japan Childhood Leukemia Study Group (JACLS) to improve outcomes in non-T ALL. Between April 2002 and March 2008, 1138 children with non-T ALL were enrolled in the JACLS ALL-02 trial.
Autor:
John A. Lust, Suzanne R. Hayman, Surendra Dasari, David L. Murray, Eli Muchtar, Dragan Jevremovic, A L Fonder, Francis K. Buadi, Miriam Hobbs, Yi Lisa Hwa, Mindy C. Kohlhagen, Martha Q. Lacy, Steven R. Zeldenrust, David Dingli, Angela Dispenzieri, Nelson Leung, Steve Russell, Ronald S. Go, Morie A. Gertz, Taxiarchis Kourelis, Bonnie K. Arendt, Robert A. Kyle, Shaji Kumar, Wilson I. Gonsalves, S. Vincent Rajkumar, Rahma Warsame, Prashant Kapoor
Publikováno v:
Blood Cancer Journal, Vol 10, Iss 2, Pp 1-5 (2020)
Blood Cancer Journal
Blood Cancer Journal
In patients with immunoglobulin light-chain (AL) amyloidosis, depth of hematologic response correlates with both organ response and overall survival. Our group has demonstrated that screening with a matrix-assisted laser desorption/ionization-time-of