Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jacob H"'
Autor:
Romy de Laat-Kremers, Marina Loizou, Scott Tawaga, Jacob H. Rand, Bas de Laat, Maria T DeSancho
Publikováno v:
Blood. 140:5666-5667
Autor:
Mats Jerkeman, Martin Hutchings, Riikka Räty, Karin Fahl Wader, Anna Laurell, Jacob H. Christensen, Hanne Kuitunen, Christian Winther Eskelund, Kirsten Groenbaek, Carsten Utoft Niemann, Christian H. Geisler, Arne Kolstad
Publikováno v:
Jerkeman, M, Hutchings, M, Räty, R, Wader, K F, Laurell, A, Kuitunen, H, Eskelund, C W, Groenbaek, K, Niemann, C U, Geisler, C H, Kolstad, A & Christensen, J H 2020, ' Ibrutinib-Lenalidomide-Rituximab in Patients with Relapsed/Refractory Mantle Cell Lymphoma: Final Results from the Nordic Lymphoma Group MCL6 (PHILEMON) Phase II Trial ', Blood, vol. 136, no. Suppl. 1, pp. 36 . https://doi.org/10.1182/blood-2020-133298
Introduction: In spite of improvements in treatment of mantle cell lymphoma (MCL), this is still considered an incurable lymphoma entity, and the majority of patients eventually relapse. Ibrutinib is a very active agent in MCL, but in vitro has been
Autor:
Karin E. Smedby, Katie Yuan Zhu, Alina S. Gerrie, Knut B. Smeland, Pär Josefsson, Katherine Colvin, Lasse Hjort Jakobsen, Chan Yoon Cheah, Kevin W. Song, Jon Bjoern, T.C. El-Galaly, Ingemar Lagerlöf, Fredrik Ellin, Harald Holte, Daniel Molin, Tove Wästerlid, Matthew J. Maurer, Yngvild Nuvin Blaker, Jacob Haaber Christensen, Jacob H. Grauslund, Gita Thanarajasingam, Thomas M. Habermann, Judit Jørgensen
Publikováno v:
Ellin, F, Smeland, K B, Wästerlid, T, Christensen, J H, Jørgensen, J, Josefsson, P L, Holte, H, Blaker, Y N, Grauslund, J H, Bjørn, J, Molin, D G, Lagerlöf, I, Smedby, K E E, Colvin, K, Thanarajasingam, G, Maurer, M J, Habermann, T M, Song, K, Zhu, K Y, Gerrie, A S, Cheah, C Y, El-Galaly, T C & Jakobsen, L H 2019, ' Inferior Outcomes for Older Patients in the Adolescent and Young Adult (AYA) Population with Burkitt Lymphoma Treated with Intensive Immunochemotherapy : An International Study of 108 Patients ', Blood, vol. 134, no. Suppl. 1, 4113 . https://doi.org/10.1182/blood-2019-127995
Introduction: Non-endemic Burkitt lymphoma (BL) is a rare and highly aggressive B-cell malignancy, of whom a substantial number are adolescents and young adults (AYAs). In this particular group of patients, the balance between efficacy and long-term
Autor:
Pär Josefsson, Fredrik Ellin, Yngvild Nuvin Blaker, Alina S. Gerrie, Harald Holte, Lasse Hjort Jakobsen, Knut B. Smeland, Karin Ekstroem Smedby, Judit Jørgensen, Katherine Colvin, Jon Bjørn, Ingemar Lagerlöf, Tove Wästerlid, Daniel Molin, Chan Yoon Cheah, Jacob Haaber Christensen, Jacob H. Grauslund, Tarec Christoffer El-Galaly, Gita Thanarajasingam
Publikováno v:
Jakobsen, L H, Ellin, F, Smeland, K B, Wästerlid, T, Christensen, J H, Jørgensen, J, Josefsson, P L, Holte, Jr., H, Blaker, Y N, Grauslund, J H, Bjørn, J, Molin, D, Lagerlöf, I, Smedby, K E, Colvin, K, Thanarajasingam, G, Gerrie, A S, Cheah, C Y & El-Galaly, T C 2018, ' Normalization of Survival and No Relapses after One Year in Adult Burkitt Lymphoma Patients Treated with Intensive Immunochemotherapy : An International Study of 159 Real-World Patients ', Blood, vol. 132, no. Suppl. 1, pp. 452 . https://doi.org/10.1182/blood-2018-99-111748
Jakobsen, L H, Ellin, F, Smeland, K B, Wasterlid, T, Christensen, J H, Jorgensen, J, Josefsson, P L, Holte, Jr., H, Blaker, Y N, Grauslund, J H, Bjorn, J, Molin, D, Lagerlof, I, Smedby, K E, Colvin, K, Thanarajasingam, G, Gerrie, A S, Cheah, C Y & El-Galaly, T C 2018, ' Normalization of Survival and No Relapses after One Year in Adult Burkitt Lymphoma Patients Treated with Intensive Immunochemotherapy: An International Study of 159 Real-World Patients ', Blood, vol. 132, no. Suppl. 1 . https://doi.org/10.1182/blood-2018-99-111748
Jakobsen, L H, Ellin, F, Smeland, K B, Wasterlid, T, Christensen, J H, Jorgensen, J, Josefsson, P L, Holte, Jr., H, Blaker, Y N, Grauslund, J H, Bjorn, J, Molin, D, Lagerlof, I, Smedby, K E, Colvin, K, Thanarajasingam, G, Gerrie, A S, Cheah, C Y & El-Galaly, T C 2018, ' Normalization of Survival and No Relapses after One Year in Adult Burkitt Lymphoma Patients Treated with Intensive Immunochemotherapy: An International Study of 159 Real-World Patients ', Blood, vol. 132, no. Suppl. 1 . https://doi.org/10.1182/blood-2018-99-111748
Background: Non-endemic Burkitt lymphoma (BL) is a rare B-cell malignancy characterized by extreme tumor proliferation, frequent extranodal involvement, and the genetic hallmark of a MYC gene rearrangement. Despite an often dramatic initial presentat
Autor:
Ljiljana V. Vasovic, Bas de Laat, Ruchika Goel, Cuicui Bai, Jacob H. Rand, Sheshadri Narayanan, Xiao Xuan Wu, Saartje Bloemen
Publikováno v:
Blood. 132:3790-3790
Background: Antiphospholipid Syndrome (APS) is associated with clinical thrombosis manifestations. However, it is characterized as prolongation of lag time in phospholipid (PL) dependent laboratory coagulation assays, a reflection of the paradoxical
Publikováno v:
Blood. 117:6777-6785
The acquired von Willebrand syndrome (AVWS) is a bleeding disorder that is frequently unrecognized or is misdiagnosed as von Willebrand disease. AVWS is characterized by structural or functional defects of von Willebrand factor (VWF) that are seconda
Autor:
Xiao-Xuan Wu, Pojen P. Chen, James J. Hathcock, Harry A.M. Andree, Jacob H. Rand, Douglas J. Taatjes, Anthony W. Ashton, Anthony S. Quinn
Publikováno v:
Blood. 115:2292-2299
Annexin A5 (AnxA5) is a potent anticoagulant protein that crystallizes over phospholipid bilayers (PLBs), blocking their availability for coagulation reactions. Antiphospholipid antibodies disrupt AnxA5 binding, thereby accelerating coagulation react
Autor:
James J. Hathcock, Xiao-Xuan Wu, Douglas J. Taatjes, Jacob H. Rand, Anthony S. Quinn, Pojen P. Chen
Publikováno v:
Blood. 112:1687-1695
Treatment with the antimalarial drug hydroxychloroquine (HCQ) has been associated with reduced risk of thrombosis in the antiphospholipid (aPL) syndrome (APS) and, in an animal model of APS, with reduction of experimentally induced thrombosis. Recogn
Autor:
Xiao-Xuan Wu, Ronald H. W. M. Derksen, Jacob H. Rand, Bas de Laat, Menno van Lummel, Philip G. de Groot
Publikováno v:
Blood. 109:1490-1494
The paradoxical correlation between thrombosis and the lupus anticoagulant (LAC) effect is an enigmatic feature of the antiphospholipid (aPL) syndrome. The Dutch authors previously reported that thrombosis-related anti–β2-glycoprotein I (β2GPI) a
Autor:
Jacob H. Hanna, Noam Weizman, Tal I. Arnon, Ofer Mandelboim, Guy Steuer, Huda Mussaffi, Maher Deeb, Hannah Blau, Suhair Hanna
Publikováno v:
Blood. 106:3465-3473
Chemokines play a pivotal role in homeostatic and inflammatory migration of naive and activated natural killer (NK) subsets. Recent studies have shown that aberrant chemokine receptor expression on certain immune cells underlies the pathogenesis of c