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pro vyhledávání: '"551"'
Autor:
Alan A. Dombkowski, Larry H. Matherly, Yubin Ge, Jeffrey W. Taub, Yaddanapudi Ravindranath, David L. Becton, Katherine M. LaFiura, Ravikiran S. Yedidi, Gita Massey, Howard J. Weinstein, Steven Buck, Mark Stout, Dana Tatman
Publikováno v:
Blood. 107:1570-1581
Children with Down syndrome (DS) with acute megakaryocytic leukemia (AMkL) have very high survival rates compared with non-DS AMkL patients. Somatic mutations identified in the X-linked transcription factor gene, GATA1, in essentially all DS AMkL cas
Autor:
Venkatesha Basrur, Andrew G. Muntean, Lili Chen, Joel Bronstein, Tao Xu, Cailin Collins, Kojo S.J. Elenitoba-Johnson, Sung Soo Park, Honglai Zhang, Jingya Wang, Rork Kuick, Jay L. Hess, Kim Kyoung Ha, Jean François Rual
Publikováno v:
Blood. 124:3533-3533
HOXA9 helps maintain the balance between hematopoietic stem/progenitor cell self-renewal and myeloid/lymphoid cell differentiation in the bone marrow (BM). HOXA9 encodes a homeodomain-containing transcription factor, which mediates its function in co