Zobrazeno 1 - 10
of 16
pro vyhledávání: '"133"'
Autor:
Hongmin Wang, Li Xiang, Lu Ying, Zheng Shuangqing, Junbo Hu, Chunyan Li, Mao Dechang, Zhuoya Li, Mei Xu, Luan Yunpeng, Yue Xing, Li Zhipeng, Yanmei Li, Luan Yunqi, Huaning Wang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 110960-(2021)
The root of Codonopis bulleynana Forest ex Diels (cbFeD), a tonic food widely used in Yunnan Province of China, was found to have a wide range of pharmacological effects. The present study was designed to investigate the anti-fibrotic effect of water
Autor:
Hao Xue, Ying Cao, Gang Li, Danqing Xin, Tingting Li, Hongfei Ke, Lin Yuan, Min Han, Xiaofan Guo, Xili Chu, Zhen Wang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 111048-(2021)
Subarachnoid hemorrhage (SAH) is an acute and severe disease with high disability and mortality. Inflammatory reactions have been proven to occur throughout SAH. Extracellular vesicles derived from mesenchymal stem cells (MSCs-EVs) have shown broad p
Autor:
Ali Rashidy-Pour, Mohammad Saeedi
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 110995-(2021)
Chronic stress and high levels of glucocorticoids produce functional and structural changes in brain and especially in the hippocampus, an important limbic system structure that plays a key role in cognitive functions including learning and memory. A
Autor:
Yunsen Zhang, Xiaobo Wang, Xiaopeng Ai, Jinrong Bai, Xiaorui Chen, Xianli Meng, Yi Zhang, Ce Tang, Ya Hou
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 110985-(2021)
Gallic acid (GA), also known as 3,4,5-trihydroxybenzoic acid, is a natural secondary metabolite and widely isolated from various fruits, plants and nuts. In recent years, GA has received increasing attention for its powerful anti-inflammatory propert
Autor:
Jing Xiong, Linfeng Dai, Qingzong Hu, Li Zhu, Lei Wang, Chaoyang Zheng, Yang Chen, Huiqi Yuan, Ziqing Song
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 110949-(2021)
Autophagy has been implicated in the pathogenesis of chronic kidney disease (CKD). Transcription factor EB (TFEB) is a master controller of autophagy. However, the pathophysiological roles of TFEB in modulating autophagy and tubulointerstitial injury
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 110946-(2021)
Wnt signaling is one of the key cascades regulating normal tissue development and has been tightly associated with cancer. The Wnt signaling can be subdivided into two categories: canonical & noncanonical. Noncanonical Wnt signaling pathways mainly i
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 110917-(2021)
Scutellaria baicalensis Georgi., a plant used in traditional Chinese medicine, has multiple biological activities, including anti-inflammatory, antiviral, antitumor, antioxidant, and antibacterial effects, and can be used to treat respiratory tract i
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 111089-(2021)
Osteoarthritis is a chronic, systemic and inflammatory disease. However, the pathogenesis and understanding of RA are still limited. Ubiquitin-specific protease 13 (USP13) belongs to the deubiquitinating enzyme (DUB) superfamily, and has been implica
Autor:
Lexi Huang, Ying An, Chao Wang, Jiqiu Hou, Jingyun Jia, Di Ma, Yali Chen, Haibin Zhao, Huihui Jin
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 111015-(2021)
Aims Over-expression of CXCR4 activates nuclear translocation of NF-κB, induces high expression of NLRP3, GSDMD, IL-1β and IL-18, which promotes severe inflammatory response following myocardial infarction. Previous studies revealed inflammation in
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 110967-(2021)
Despite the role of curcumin in controlling inflammation, angiogenesis, and cancer in human cells, its therapeutic use is limited. The reasons are quick metabolic breakdown, low aqueous solubility, and bioavailability. This study describes the advant