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Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 311:H276-H285
Parasympathetic activity is often reduced in hypertension and can elicit anti-inflammatory mechanisms. Thus we hypothesized that chronic vagal nerve stimulation (VNS) may alleviate cardiovascular end-organ damage in stroke-prone spontaneously hyperte
Autor:
Jesus Serrano-Lomelin, Lindsay Mills, Nee Scze Khoo, Etienne Fortin-Pellerin, Po-Yin Cheung, James Y. Coe, Lisa K. Hornberger
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 310:H598-H607
Doppler studies at rest suggest left ventricular (LV) diastolic function rapidly improves from the neonate to infant. Whether this translates to its response to hemodynamic challenges is uncertain. We sought to explore the impact of early LV maturati
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 310:H123-H131
The sympathetic and pressor responses to exercise are exaggerated in hypertension. However, the underlying mechanisms causing this abnormality remain to be fully elucidated. Central command, a neural drive originating in higher brain centers, is know
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 309:H1740-H1752
Using vagus nerve stimulation (VNS), we sought to determine the contribution of vagal afferents to efferent control of cardiac function. In anesthetized dogs, the right and left cervical vagosympathetic trunks were stimulated in the intact state, fol
Autor:
Tatsuo Takamiya, Pradeep S. Rajendran, Aman Mahajan, Daigo Yagishita, Kalyanam Shivkumar, Kentaro Yamakawa, Marmar Vaseghi, Eileen L. So
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 309:H1579-H1590
Vagal nerve stimulation (VNS) has been shown to have antiarrhythmic effects, but many of these benefits were demonstrated in the setting of vagal nerve decentralization. The purpose of this study was to evaluate the role of afferent fiber activation
Autor:
Antoine Vieillard-Baron, Xavier Repessé, Julia Fink, Alain Beauchet, Guillaume Belliard, Cyril Charron, Michel Slama, Florian Deleu
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 309:H1003-H1007
Mean systemic filling pressure (Pmsf) is a major determinant of venous return. Its value is unknown in critically ill patients (ICU). Our objectives were to report Pmsf in critically ill patients and to look for its clinical determinants, if any. We
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 309:H557-H564
The influences of severe heat stroke (HS) on cardiovascular function during recovery are incompletely understood. We hypothesized that HS would elicit a heart rate (HR) increase persisting through 24 h of recovery due to hemodynamic, thermoregulatory
Autor:
Junko Shibayama, Tyson G. Taylor, Alexey V. Zaitsev, Vivek Garg, Paul W. Venable, Katie J. Sciuto, Mark Warren
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 308:H485-H499
Mitochondrial membrane potential (ΔΨm) depolarization has been implicated in the loss of excitability (asystole) during global ischemia, which is relevant for the success of defibrillation and resuscitation after cardiac arrest. However, the relati
Autor:
Bronya Vaschillo, Eun Young Mun, Vladimir A. Fonoberov, Adriana Mezić, Maria Fonoberova, Evgeny G. Vaschillo, Jennifer F. Buckman, Igor Mezic, Marsha E. Bates
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 307:H1073-H1091
Heart rate variability biofeedback intervention involves slow breathing at a rate of ∼6 breaths/min (resonance breathing) to maximize respiratory and baroreflex effects on heart period oscillations. This intervention has wide-ranging clinical benef
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 306:H1464-H1471
Chronic heart failure (CHF) is responsible for significant morbidity and mortality worldwide, mainly as a result of neurohumoral activation. Acupuncture has been used to treat a wide range of diseases and conditions. In this study, we investigated th