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Autor:
Amanda Nicoll, David Moore, Francesco Amico, Adam Doyle, Brad Hockey, Siddharth Sood, Bridget Bishop, Dolores B. Njoku, Alexandra Gorelik, Nicholas Hannah, Danny Liew
Publikováno v:
Alimentary Pharmacology & Therapeutics. 49:940-951
Background Volatile anaesthetics are known to cause drug-induced liver injury, a hepatotoxic reaction characterised by antibodies to trifluoroacetylated lipid and protein adducts and cytochrome p450 2E1. The incidence of volatile anaesthetic drug-ind
Autor:
Jing Pan, Hanjing Lv, Qiang Chen, Hongmei Ding, Mengru Zhang, Xianghuai Xu, Ran Dong, Yiming Yu, Cuiqin Shi, Zhongmin Qiu, Li Yu
Publikováno v:
Alimentary Pharmacology & Therapeutics. 49:714-722
Background Neuromodulators are considered potential therapeutic options for refractory gastro-oesophageal reflux-induced chronic cough. Aim To compare the efficacy of gabapentin and baclofen in patients with suspected refractory gastro-oesophageal re
Autor:
Vikram Rangan, Anthony Lembo
Publikováno v:
Alimentary Pharmacology & Therapeutics. 54:500-501
Autor:
Frank L. Ross, Renie Guilliod, Raymond K. Cross, David I. Fudman, Shannon Chang, Benjamin D. Levine, Laura E. Raffals, David Hudesman, Jay C. Buckey, M. Hassan Murad, Corey A. Siegel, Kinjal N. Sethuraman, Michael Winter, Charlotte Sadler, Gary N. Toups, Parambir S. Dulai, Ernest L. Chiu, Michael Chiorean, Tasneem Ahmed, James R. Holm
Publikováno v:
Alimentary Pharmacology & Therapeutics.
BACKGROUND: Hyperbaric oxygen has been reported to improve disease activity in hospitalised ulcerative colitis (UC) patients. AIM: To evaluate dosing strategies with hyperbaric oxygen for hospitalised UC patients. METHODS: We enrolled UC patients hos
Publikováno v:
Alimentary Pharmacology & Therapeutics. 49:1246-1247
Publikováno v:
Alimentary Pharmacology & Therapeutics. 40:771-779
SummaryBackground Opioid-induced constipation (OIC) is a common adverse effect of opioid therapy. Aim To evaluate the long-term safety and tolerability of naloxegol, an oral, peripherally acting μ-opioid receptor antagonist (PAMORA), in patients wit
Publikováno v:
Alimentary Pharmacology & Therapeutics. 39:557-568
Summary Background Propranolol is recommended for prophylaxis of variceal bleeding in cirrhosis. Carvedilol is a nonselective beta-blocker with a mild anti-alfa-1-adrenergic activity. Several studies have compared carvedilol and propranolol, yielding
Publikováno v:
Alimentary Pharmacology & Therapeutics. 38:365-376
SummaryBackground Infliximab is typically administered intravenously via 2- to 3-h duration infusions. Infusions are time-consuming and costly. Shorter duration infusions are administered at some centres. Limited safety data are available on shorter
Publikováno v:
Alimentary Pharmacology & Therapeutics. 37:947-952
Summary Background Current guidelines recommend the cessation of clopidogrel therapy 5 days and 7–10 days prior to colonoscopic polypectomy. Recent studies have advocated for continued clopidogrel as post-polypectomy bleeding (PPB) rates have been
Autor:
O B Schaffalitzky de Muckadell, Jesper Hallas, Annmarie Touborg Lassen, R. dePont Christensen, Michael Dall
Publikováno v:
Dall, M, Christensen, R D, Schaffalitzky de Muckadell, O B, Lassen, A T & Hallas, J 2012, ' Re-prescribing of causative drugs in persons discharged after serious drug-induced upper gastrointestinal bleeding ', Alimentary Pharmacology and Therapeutics, vol. 35, no. 8, pp. 948-54 . https://doi.org/10.1111/j.1365-2036.2012.05006.x
Summary Background Several drug classes are known to be associated with serious upper gastrointestinal bleeding (UGIB), among others NSAID, low-dose acetylsalicylic acid (ASA), vitamin K antagonists (VKA), clopidogrel and selective serotonin reuptake