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Autor:
Frith, Daniel
Acute traumatic coagulopathy (ATC) is a recently identified entity describing an early impairment of haemostasis after injury. Retrospective observational studies have associated it with a significant increase in patient morbidity and mortality. It d
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.545986
Autor:
Wrench, David John
Follicular lymphoma (FL) is the second most common form of non-Hodgkin lymphoma and at least a third of cases undergo aggressive transformation (t-FL), most frequently to diffuse large B-cell lymphoma. This study examined the role of germline and acq
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.545938
Autor:
Payne, Elspeth
Several congenital disorders of human haematopoiesis including Diamond- Blackfan anaemia result from heterozygous loss of genes involved in ribosome biogenesis. Further, hemizygosity for ribosomal protein gene RPS14 has been implicated in the pathoge
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.535839
Autor:
Su, Bo
The apoptotic pathway plays critical roles in regulating lymphocyte survival throughout B cell development, maturation and differentiation. The whole process involves clonal expansion. In the normal B lymphocyte population the majority of cells and t
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.528424
MicroRNAs (miRNAs), a group of highly-conserved, small (19-26 nucleotides), non-coding RNAs, are one of the largest gene families of the genome. They are believed to control several pathways including haematopoiesis and are implicated in a number of
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511370
Autor:
Ó Riain, Ciarán Liam
Follicular Lymphoma (FL) is a common B cell Non-Hodgkin Lymphoma with a median survival of 8-10 years. Patients frequently undergo transformation to a more aggressive lymphoma and this is associated with drastically reduced survival. The hallmark of
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538360
Autor:
De Vita, Serena
AMKL (acute megakaryoblastic leukaemia) accounts for at least 50% of all cases of acute myeloid leukaemia (AML) associated with Down Syndrome (DS). Every tenth neonate with DS develops Transient Myeloproliferative Disorder (TMD), a self-regressing ne
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511402
Autor:
Le Dieu, Helen Rifca
Understanding the immune system in patients with cancer and how it interacts with malignant cells is critical for the development of successful immunotherapeutic strategies at a time when novel cancer treatment approaches are required. Acute myeloid
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511371
Autor:
Lee, Abigail Mary
The natural history of follicular lymphoma is heterogeneous with numerous relapses and remissions over many years. A substantial number of patients suffer an aggressive disease course with death due to disease within 5 years of diagnosis. The prognos
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516712
Autor:
Eagle, Gina L.
Chronic Lymphocytic Leukaemia (CLL) is the most common adult Leukaemia in the UK, Western Europe and America. It is a malignancy of naive B-cells. The clinical course of patients with CLL is heterogeneous; some patients survive for years without trea
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.507818