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Genome-wide multiple sequence alignments (MSAs) are a necessary prerequisite for an increasingly diverse collection of comparative genomic approaches. Here we present a versatile method that generates high-quality MSAs for non-protein-coding sequence
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https://ul.qucosa.de/api/qucosa%3A31951/attachment/ATT-0/
Evolutionarily conserved non-coding genomic sequences represent a potentially rich source for the discovery of gene regulatory regions. Since these elements are subject to stabilizing selection they evolve much slower than adjacent non-functional DNA
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https://ul.qucosa.de/id/qucosa%3A31997
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https://ul.qucosa.de/api/qucosa%3A31997/attachment/ATT-0/
Autor:
Tanzer, Andrea, Stadler, Peter F.
Many of the known microRNAs are encoded in polycistronic transcripts. Here, we reconstruct the evolutionary history of the mir17 microRNA clusters which consist of miR-17, miR-18, miR-19a, miR-19b, miR-20, miR-25, miR-92, miR-93, miR-106a, and miR-10
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https://ul.qucosa.de/id/qucosa%3A31911
https://ul.qucosa.de/api/qucosa%3A31911/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A31911/attachment/ATT-0/