Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kajantie, Eero"'
Autor:
Choudhary P; Research Unit of Population Health, Faculty of Medicine, University of Oulu, 90014, Oulu, Finland. Priyanka.Choudhary@oulu.fi., Monasso GS; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Karhunen V; Research Unit of Population Health, Faculty of Medicine, University of Oulu, 90014, Oulu, Finland.; Research Unit of Mathematical Sciences, Faculty of Science, University of Oulu, Oulu, Finland., Ronkainen J; Research Unit of Population Health, Faculty of Medicine, University of Oulu, 90014, Oulu, Finland., Mancano G; Medical Research Council Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, UK.; Bristol Medical School Population Health Sciences, University of Bristol, Bristol, UK., Howe CG; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., Niu Z; Department of Population and Public Health Sciences, USC Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Zeng X; Glotech, Inc., Rockville, MD, 20850, USA., Guan W; Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, 55455, USA., Dou J; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Feinberg JI; Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MA, USA., Mordaunt C; Department of Medical Micriobiology and Immunology, University of California Davis, Davis, CA, USA., Pesce G; Epidemiology of Allergic and Respiratory Diseases (EPAR) team, Faculté de Médecine Saint-Antoine, Institute Pierre Louis d'Epidemiologie et Sante Publique (IPLESP), Sorbonne Université and INSERM, Paris, France.; Paris-Saclay University, Paris-South University, UVSQ, Center for Research in Epidemiology and Population Health (CESP), INSERM, Villejuif, France., Baïz N; Institute Desbrest of Epidemiology and Public Health, University of Montpellier and INSERM, Montpellier, France., Alfano R; Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium., Martens DS; Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium., Wang C; Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium., Isaevska E; Cancer Epidemiology Unit, Department of Medical Sciences, University of Turin and CPO-Piemonte, Torino, Italy., Keikkala E; Department of Obstetrics and Gynaecology, Research Unit of Clinical Medicine, Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland.; Finnish Institute for Health and Welfare, Population Health Unit, Public Health and Welfare, Helsinki and Oulu, Finland., Mustaniemi S; Department of Obstetrics and Gynaecology, Research Unit of Clinical Medicine, Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland.; Finnish Institute for Health and Welfare, Population Health Unit, Public Health and Welfare, Helsinki and Oulu, Finland., Thio CHL; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Fraszczyk E; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Tobi EW; Department of Obstetrics and Gynaecology, Division of Obstetrics and Prenatal Medicine, Erasmus MC, University Medical Center, 3000 CA, Rotterdam, the Netherlands., Starling AP; Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Cosin-Tomas M; ISGlobal (Barcelona Institute for Global Health), Barcelona Biomedical Research Park (PRBB), Doctor Aiguader, 88, 08003, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain., Urquiza J; ISGlobal (Barcelona Institute for Global Health), Barcelona Biomedical Research Park (PRBB), Doctor Aiguader, 88, 08003, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain., Röder S; Department for Environmental Immunology, Helmholtz Centre for Environmental Research, UFZ, Leipzig, Germany., Hoang TT; Epidemiology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA., Page C; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.; Oslo Centre for Biostatistics and Epidemiology, Section for Research Support, Oslo University Hospital, Oslo, Norway., Jima DD; Center for Human Health and the Environment, North Carolina State University, Raleigh, NC, 27606, USA.; Bioinformatics Research Center, North Carolina State University, Raleigh, NC, 27606, USA., House JS; Center for Human Health and the Environment, North Carolina State University, Raleigh, NC, 27606, USA.; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, Durham, NC, 27709, USA., Maguire RL; Department of Biological Sciences, North Carolina State University, Raleigh, NC, USA.; Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC, 27701, USA., Ott R; Institute of Diabetes Research, Helmholtz Munich, German Research Center for Environmental Health, Munich, Germany.; Forschergruppe Diabetes eV, Neuherberg, Germany., Pawlow X; Institute of Diabetes Research, Helmholtz Munich, German Research Center for Environmental Health, Munich, Germany.; Forschergruppe Diabetes eV, Neuherberg, Germany., Sirignano L; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Zillich L; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Malmberg A; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Rauschert S; Telethon Kids Institute, Perth, WA, Australia., Melton P; Menzies Institute of Medical Research, University of Tasmania, Hobart, TAS, Australia.; University of Western Australia, School of Population and Global Health, Perth, WA, Australia., Gong T; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Karlsson R; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Fore R; Division of Chronic Disease Research Across the Lifecourse (CoRAL), Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, MA, USA., Perng W; Department of Epidemiology and the Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Laubach ZM; Department of Ecology and Evolutionary Biology, University of Colorado Boulder, Boulder, CO, USA., Czamara D; Department Genes and Environment, Max Planck Institute for Psychiatry, Kraepelinstrasse 2+10, 80804, Munich, Germany., Sharp G; Medical Research Council Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, UK.; Bristol Medical School Population Health Sciences, University of Bristol, Bristol, UK.; School of Psychology, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK., Breton CV; Department of Population and Public Health Sciences, USC Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Schisterman E; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Yeung E; Epidemiology Branch, Division of Population Health Research, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, 20817, USA., Mumford SL; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Epidemiology Branch, Division of Population Health Research, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, 20817, USA., Fallin MD; Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MA, USA., LaSalle JM; Department of Medical Micriobiology and Immunology, University of California Davis, Davis, CA, USA., Schmidt RJ; Department of Public Health Sciences, School of Medicine, University of California Davis (UC Davis), Davis, CA, USA., Bakulski KM; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Annesi-Maesano I; Institute Desbrest of Epidemiology and Public Health, University of Montpellier and INSERM, Montpellier, France., Heude B; Université de Paris Cité, Inserm, INRAE, Centre of Research in Epidemiology and StatisticS (CRESS), F-75004, Paris, France., Nawrot TS; Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium., Plusquin M; Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium., Ghantous A; Epigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France., Herceg Z; Epigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France., Nisticò L; Centre for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità, Viale Regina Elena, Rome, Italy., Vafeiadi M; Department of Social Medicine, School of Medicine, University of Crete, Heraklion, Crete, Greece., Kogevinas M; Barcelona Institute for Global Health (ISGlobal), Barcelona, Spain.; Centro de Investigación Biomédicaen Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain., Vääräsmäki M; Department of Obstetrics and Gynaecology, Research Unit of Clinical Medicine, Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland.; Finnish Institute for Health and Welfare, Population Health Unit, Public Health and Welfare, Helsinki and Oulu, Finland., Kajantie E; Finnish Institute for Health and Welfare, Population Health Unit, Public Health and Welfare, Helsinki and Oulu, Finland.; Clinical Medicine Research Unit, Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland.; Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Snieder H; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Corpeleijn E; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Steegers-Theunissen RPM; Department of Obstetrics and Gynaecology, Division of Obstetrics and Prenatal Medicine, Erasmus MC, University Medical Center, 3000 CA, Rotterdam, the Netherlands., Yang IV; Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO, USA.; Center for Genes, Environment and Health, National Jewish Health, Denver, CO, USA., Dabelea D; Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Fossati S; ISGlobal (Barcelona Institute for Global Health), Barcelona Biomedical Research Park (PRBB), Doctor Aiguader, 88, 08003, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain., Zenclussen AC; Department for Environmental Immunology, Helmholtz Centre for Environmental Research, UFZ, Leipzig, Germany., Herberth G; Department for Environmental Immunology, Helmholtz Centre for Environmental Research, UFZ, Leipzig, Germany., Magnus M; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway., Håberg SE; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway., London SJ; Epidemiology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA., Munthe-Kaas MC; Department of Pediatrics, Oncology and Hematology, Oslo University Hospital, Oslo, Norway.; Norwegian Institute of Public Health, Oslo, Norway., Murphy SK; Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC, 27701, USA., Hoyo C; Center for Human Health and the Environment, North Carolina State University, Raleigh, NC, 27606, USA.; Department of Biological Sciences, North Carolina State University, Raleigh, NC, USA., Ziegler AG; Institute of Diabetes Research, Helmholtz Munich, German Research Center for Environmental Health, Munich, Germany.; Forschergruppe Diabetes eV, Neuherberg, Germany.; Technical University Munich, School of Medicine, Forschergruppe Diabetes at Klinikum rechts der Isar, Munich, Germany., Hummel S; Institute of Diabetes Research, Helmholtz Munich, German Research Center for Environmental Health, Munich, Germany.; Forschergruppe Diabetes eV, Neuherberg, Germany.; Technical University Munich, School of Medicine, Forschergruppe Diabetes at Klinikum rechts der Isar, Munich, Germany., Witt SH; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Center for Innovative Psychiatric and Psychotherapeutic Research, Biobank, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Streit F; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Frank J; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Räikkönen K; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Lahti J; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Huang RC; Telethon Kids Institute, Perth, WA, Australia.; Edith Cowan University, School of Medicine and Health Sciences, Joondalup, WA, Australia., Almqvist C; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Pediatric Allergy and Pulmonology Unit at Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden., Hivert MF; Division of Chronic Disease Research Across the Lifecourse (CoRAL), Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, MA, USA.; Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA., Jaddoe VWV; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Järvelin MR; Research Unit of Population Health, Faculty of Medicine, University of Oulu, 90014, Oulu, Finland.; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, UK.; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK., Kantomaa M; Research Unit of Population Health, Faculty of Medicine, University of Oulu, 90014, Oulu, Finland., Felix JF; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Sebert S; Research Unit of Population Health, Faculty of Medicine, University of Oulu, 90014, Oulu, Finland.
Publikováno v:
Molecular psychiatry [Mol Psychiatry] 2024 Feb; Vol. 29 (2), pp. 348-358. Date of Electronic Publication: 2023 Dec 05.
Autor:
Beaumont RN; Department of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK., Flatley C; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Genetics and Bioinformatics, Health Data and Digitalization, Norwegian Institute of Public Health, Oslo, Norway., Vaudel M; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway., Wu X; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Chen J; Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Moen GH; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Frazer Institute, The University of Queensland, Brisbane, Queensland, Australia.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Population Health Science, Bristol Medical School, University of Bristol, Bristol, UK.; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia., Skotte L; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Helgeland Ø; Department of Genetics and Bioinformatics, Health Data and Digitalization, Norwegian Institute of Public Health, Oslo, Norway.; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway., Solé-Navais P; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Banasik K; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark., Albiñana C; National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark., Ronkainen J; Research Unit of Population Health, University of Oulu, Oulu, Finland., Fadista J; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.; Department of Clinical Sciences, Lund University Diabetes Centre, Malmö, Sweden.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Stinson SE; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Trajanoska K; Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Human Genetics, McGill University, Montréal, Québec, Canada., Wang CA; School of Medicine and Public Health, College of Medicine, Public Health and Wellbeing, The University of Newcastle, Newcastle, New South Wales, Australia.; Hunter Medical Research Institute, New Lambton Heights, Newcastle, New South Wales, Australia., Westergaard D; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.; Department of Obstetrics and Gynecology, Copenhagen University Hospital, Hvidovre, Denmark.; Methods and Analysis, Statistics Denmark, Copenhagen, Denmark., Srinivasan S; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, UK., Sánchez-Soriano C; Centre for Cardiovascular Science, The University of Edinburgh, Edinburgh, UK., Bilbao JR; Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country (UPV/EHU), Leioa, Spain.; Biobizkaia Health Research Institute, Barakaldo, Spain.; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Disorders (CIBERDEM), Barcelona, Spain., Allard C; Centre de recherche du Centre Hospitalier de l'Universite de Sherbrooke, Sherbrooke, Québec, Canada., Groleau M; Département de Biologie, Faculté des Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada., Kuulasmaa T; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland., Leirer DJ; Department of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK., White F; Département de Biologie, Faculté des Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada., Jacques PÉ; Centre de recherche du Centre Hospitalier de l'Universite de Sherbrooke, Sherbrooke, Québec, Canada.; Département de Biologie, Faculté des Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada., Cheng H; Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Hao K; Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Andreassen OA; NORMENT Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Åsvold BO; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, Norway.; Department of Endocrinology, Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Atalay M; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland., Bhatta L; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway., Bouchard L; Department of Biochemistry and Functional Genomics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada.; Clinical Department of Laboratory Medicine, Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Saguenay-Lac-St-Jean-Hôpital Universitaire de Chicoutimi, Saguenay, Québec, Canada., Brumpton BM; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, Norway.; Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Brunak S; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark., Bybjerg-Grauholm J; Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.; iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark., Ebbing C; Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway., Elliott P; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Engelbrechtsen L; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Obstetrics and Gynecology, Herlev Hospital, Herlev, Denmark., Erikstrup C; Department Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.; Department Clinical Medicine, Aarhus University, Aarhus, Denmark., Estarlich M; Faculty of Nursing and Chiropody, Universitat de València, C/Menendez Pelayo, Valencia, Spain.; Epidemiology and Environmental Health Joint Research Unit, Foundation for the Promotion of Health and Biomedical Research in the Valencian Region, FISABIO-Public Health, FISABIO-Universitat Jaume I-Universitat de València, Valencia, Spain.; Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Madrid, Spain., Franks S; Institute of Reproductive and Developmental Biology, Imperial College London, London, UK., Gaillard R; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Geller F; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Grove J; iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Department of Biomedicine-Human Genetics and the iSEQ Center, Aarhus University, Aarhus, Denmark.; Center for Genomics and Personalized Medicine, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark., Hougaard DM; Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.; iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark., Kajantie E; Research Unit of Clinical Medicine, Medical Research Center, University of Oulu, Oulu, Finland.; Population Health Unit, Finnish Institute for Health and Welfare, Helsinki and Oulu, Oulu, Finland.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Morgen CS; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark., Nohr EA; Institute of Clinical research, University of Southern Denmark, Odense, Denmark., Nyegaard M; Department of Health Science and Technology, Aalborg University, Aalborg, Denmark., Palmer CNA; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, UK., Pedersen OB; Department of Clinical Immunology, Zealand University Hospital, Køge, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Rivadeneira F; Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Sebert S; Research Unit of Population Health, University of Oulu, Oulu, Finland., Shields BM; Department of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK., Stoltenberg C; Norwegian Institute of Public Health, Oslo, Norway.; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway., Surakka I; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, USA., Thørner LW; Department of Clinical Immunology, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Ullum H; Statens Serum Institut, Copenhagen, Denmark., Vaarasmaki M; Research Unit of Clinical Medicine, Medical Research Center, University of Oulu, Oulu, Finland.; Department of Obstetrics and Gynaecology, Oulu University Hospital, Oulu, Finland., Vilhjalmsson BJ; National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark., Willer CJ; Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, USA.; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Lakka TA; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Gybel-Brask D; Psychotherapeutic Outpatient Clinic, Mental Health Services, Capital Region, Copenhagen, Denmark., Bustamante M; Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Madrid, Spain.; ISGlobal, Institute for Global Health, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Pearson ER; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, UK., Reynolds RM; Centre for Cardiovascular Science, The University of Edinburgh, Edinburgh, UK., Ostrowski SR; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Immunology, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Pennell CE; School of Medicine and Public Health, College of Medicine, Public Health and Wellbeing, The University of Newcastle, Newcastle, New South Wales, Australia.; Hunter Medical Research Institute, New Lambton Heights, Newcastle, New South Wales, Australia., Jaddoe VWV; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Felix JF; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Hattersley AT; Department of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK., Melbye M; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Danish Cancer Institute, Copenhagen, Denmark.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Lawlor DA; Population Health Science, Bristol Medical School, University of Bristol, Bristol, UK.; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, Norway., Werge T; iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Institute of Biological Psychiatry, Mental Health Services, Copenhagen University Hospital, Copenhagen, Denmark.; Lundbeck Center for Geogenetics, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark., Nielsen HS; Department of Obstetrics and Gynecology, Copenhagen University Hospital, Hvidovre, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Magnus P; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway., Evans DM; Frazer Institute, The University of Queensland, Brisbane, Queensland, Australia.; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Jacobsson B; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Genetics and Bioinformatics, Health Data and Digitalization, Norwegian Institute of Public Health, Oslo, Norway., Järvelin MR; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Center for Life Course Health Research, University of Oulu, Oulu, Finland.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Unit of Primary Health Care, Oulu University Hospital, OYS, Oulu, Finland., Zhang G; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Center for Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; March of Dimes Prematurity Research Center Ohio Collaborative, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Hivert MF; Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, MA, USA.; Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA., Johansson S; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway. stefan.johansson@uib.no.; Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway. stefan.johansson@uib.no., Freathy RM; Department of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK. r.freathy@exeter.ac.uk.; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK. r.freathy@exeter.ac.uk., Feenstra B; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark. fee@ssi.dk.; Department of Clinical Immunology, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark. fee@ssi.dk., Njølstad PR; Mohn Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway. pal.njolstad@uib.no.; Children and Youth Clinic, Haukeland University Hospital, Bergen, Norway. pal.njolstad@uib.no.
Publikováno v:
Nature genetics [Nat Genet] 2023 Nov; Vol. 55 (11), pp. 1807-1819. Date of Electronic Publication: 2023 Oct 05.
Autor:
Ahluwalia TS; Steno Diabetes Center Copenhagen, Gentofte DK2820, Denmark.; Department of Biology, The Bioinformatics Center, University of Copenhagen, Copenhagen DK2200, Denmark., Prins BP; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, The Netherlands., Abdollahi M; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, The Netherlands., Armstrong NJ; Mathematics and Statistics, Murdoch University, Perth 6150, Australia., Aslibekyan S; Department of Epidemiology, University of Alabama at Birmingham School of Public Health, Birmingham, Alabama 35233, USA., Bain L; QIMR Berghofer Medical Research Institute, Brisbane 4006, Australia., Jefferis B; Department of Primary Care & Population Health, UCL Institute of Epidemiology & Health Care, University College London, London NW3 2PF, UK., Baumert J; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg 85764, Germany., Beekman M; Department of Biomedical Data Sciences, Section of Molecular Epidemiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands., Ben-Shlomo Y; Population Health Sciences, University of Bristol, Bristol BS8 2PS, UK., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA., Mitchell BD; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21202, USA., de Geus E; Department of Biological Psychology, Behaviour and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam 1081 BT, The Netherlands.; Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam 1105 AZ, The Netherlands., Delgado GE; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim 68167, Germany., Marek D; SIB Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland., Eriksson J; Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, Centre for Bone and Arthritis Research (CBAR), University of Gothenburg, Gothenburg 41345, Sweden., Kajantie E; Chronic Disease Prevention Unit, National Institute for Health and Welfare, PO Box 30, Helsinki 00271, Finland.; Hospital for Children and Adolescents, Helsinki University Central Hospital and University of Helsinki, Helsinki 00014, Finland., Kanoni S; William Harvey Research Institute, Barts & the London Medical School, Queen Mary University of London, London EC1M 6BQ, UK., Kemp JP; The University of Queensland Diamantina Institute, The University of Queensland, Woolloongabba, Queensland 4102, Australia.; MRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol BS8 2BN, UK., Lu C; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA., Marioni RE; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh EH8 9JZ, UK., McLachlan S; Usher Institute, University of Edinburgh, Edinburgh EH8 9AG, UK., Milaneschi Y; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam 1081 HJ, The Netherlands., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, The Netherlands., Petrelis AM; Université de Lorraine, Inserm, IGE-PCV, Nancy 54000, France., Porcu E; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Monserrato (CA) 09042, Italy., Sabater-Lleal M; Cardiovascular Medicine, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm 17176, Sweden.; Unit of Genomics of Complex Diseases, Institut d'Investigació Biomèdica Sant Pau (IIB-Sant Pau), Barcelona 08041, Spain., Naderi E; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, The Netherlands., Seppälä I; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere 33520, Finland., Shah T; Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK., Singhal G; Discipline of Psychiatry, Adelaide Medical School, University of Adelaide, Adelaide 5005, Australia., Standl M; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg 85764, Germany., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald 17475, Germany., Thalamuthu A; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney 2052, Australia., Thiering E; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg 85764, Germany.; Division of Metabolic Diseases and Nutritional Medicine, Ludwig-Maximilians-University of Munich, Dr. von Hauner Children's Hospital, Munich 80337, Germany., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands., Ballantyne CM; Baylor College of Medicine, Houston, TX 77030, USA., Benjamin EJ; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA 01702, USA.; Section of Cardiovascular Medicine and Preventive Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA., Casas JP; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA 02130, USA., Toben C; Discipline of Psychiatry, Adelaide Medical School, University of Adelaide, Adelaide 5005, Australia., Dedoussis G; 44Department of Nutrition-Dietetics, Harokopio University, Athens 17671, Greece., Deelen J; Department of Biomedical Data Sciences, Section of Molecular Epidemiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.; Max Planck Institute for Biology of Ageing, Cologne 50931, Germany., Durda P; Department of Pathology and Laboratory Medicine, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA., Engmann J; Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110-1093, USA., Grallert H; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg 85764, Germany.; German Center for Diabetes Research (DZD), Neuherberg 85764, Germany., Hammarstedt A; The Lundberg Laboratory for Diabetes Research, Department of Molecular and Clinical Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg SE-41345, Sweden., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh EH8 9JZ, UK.; Department of Psychology, University of Edinburgh, Edinburgh EH8 9JZ, UK., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald 17475, Germany., Hottenga JJ; Department of Biological Psychology, Behaviour and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam 1081 BT, The Netherlands.; Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam 1105 AZ, The Netherlands., Jalkanen S; MediCity Research Laboratory, University of Turku, Turku 20520, Finland.; Department of Medical Microbiology and Immunology, University of Turku, Turku 20520, Finland., Jamshidi Y; Genetics Research Centre, Molecular and Clinical Sciences Institute, St George's University of London, London SW17 0RE, UK., Jawahar MC; Discipline of Psychiatry, Adelaide Medical School, University of Adelaide, Adelaide 5005, Australia., Jess T; 55Department of Epidemiology Research, Statens Serum Institute, Copenhagen DK2300, Denmark., Kivimaki M; Department of Epidemiology & Public Health, UCL Institute of Epidemiology & Health Care, University College London, London WC1E 7HB, UK., Kleber ME; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim 68167, Germany., Lahti J; Turku Institute for Advanced Studies, University of Turku, Turku 20014, Finland.; Department of Psychology and Logopedics, University of Helsinki, Helsinki 00014, Finland., Liu Y; Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA., Marques-Vidal P; Department of Internal Medicine, Lausanne University Hospital (CHUV), Lausanne 1011, Switzerland.; University of Lausanne, Lausanne 1011, Switzerland., Mellström D; Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, Centre for Bone and Arthritis Research (CBAR), University of Gothenburg, Gothenburg 41345, Sweden., Mooijaart SP; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands., Müller-Nurasyid M; IBE, Faculty of Medicine, Ludwig Maximilians University (LMU) Munich, Munich 81377, Germany.; Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johhanes Gutenberg University, Mainz 55101, Germany., Penninx B; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam 1081 HJ, The Netherlands., Revez JA; QIMR Berghofer Medical Research Institute, Brisbane 4006, Australia., Rossing P; Steno Diabetes Center Copenhagen, Gentofte DK2820, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen DK2200, Denmark., Räikkönen K; Department of Psychology and Logopedics, University of Helsinki, Helsinki 00014, Finland., Sattar N; BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, Glasgow G12 8TA, UK., Scharnagl H; 66Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz 8036, Austria., Sennblad B; Cardiovascular Medicine, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm 17176, Sweden.; Department of Cell and Molecular Biology, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Uppsala University, Uppsala 75124, Sweden., Silveira A; Cardiovascular Medicine, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm 17176, Sweden., Pourcain BS; MRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol BS8 2BN, UK.; Max Planck Institute for Psycholinguistics, Nijmegen XD 6525, The Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen 6525 AJ, The Netherlands., Timpson NJ; MRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol BS8 2BN, UK., Trollor J; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney 2052, Australia.; Department of Developmental Disability Neuropsychiatry, School of Psychiatry, University of New South Wales, Sydney 2031, Australia., van Dongen J; Department of Biological Psychology, Behaviour and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam 1081 BT, The Netherlands.; Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam 1105 AZ, The Netherlands., Van Heemst D; Baylor College of Medicine, Houston, TX 77030, USA., Visvikis-Siest S; Université de Lorraine, Inserm, IGE-PCV, Nancy 54000, France., Vollenweider P; Department of Internal Medicine, Lausanne University Hospital (CHUV), Lausanne 1011, Switzerland.; University of Lausanne, Lausanne 1011, Switzerland., Völker U; MediCity Research Laboratory, University of Turku, Turku 20520, Finland., Waldenberger M; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg 85764, Germany., Willemsen G; Department of Biological Psychology, Behaviour and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam 1081 BT, The Netherlands.; Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam 1105 AZ, The Netherlands., Zabaneh D; Department of Genetics, Environment and Evolution, University College London Genetics Institute, London WC1E 6BT, UK., Morris RW; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 1UD, UK., Arnett DK; Dean's Office, College of Public Health, University of Kentucky, Lexington, KY 40536, USA., Baune BT; Department of Psychiatry, Melbourne Medical School, The University of Melbourne, Parkville 3000, Australia.; Department of Psychiatry and Psychotherapy, University of Muenster, Muenster 48149, Germany.; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville 3000, Australia., Boomsma DI; Department of Biological Psychology, Behaviour and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam 1081 BT, The Netherlands.; Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam 1105 AZ, The Netherlands., Chang YC; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21202, USA., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh EH8 9JZ, UK.; Department of Psychology, University of Edinburgh, Edinburgh EH8 9JZ, UK., Deloukas P; William Harvey Research Institute, Barts & the London Medical School, Queen Mary University of London, London EC1M 6BQ, UK.; 77Centre for Genomic Health, Queen Mary University of London, London EC1M 6BQ, UK., Eriksson JG; National Institute for Health and Welfare, University of Helsinki, Helsinki 00014, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki 00014, Finland., Evans DM; The University of Queensland Diamantina Institute, The University of Queensland, Woolloongabba, Queensland 4102, Australia.; MRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol BS8 2BN, UK., Ferreira MA; QIMR Berghofer Medical Research Institute, Brisbane 4006, Australia., Gaunt T; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol BS6 2BN, UK.; Population Health Science, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK., Gudnason V; Icelandic Heart Association, Kópavogur 201, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland., Hamsten A; Cardiovascular Medicine, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm 17176, Sweden., Heinrich J; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg 85764, Germany.; Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Munich 81377, Germany.; Allergy and Lung Health Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne 3010, Australia., Hingorani A; Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK., Humphries SE; Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK., Jukema JW; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands.; Durrer Center for Cardiogenetic Research, Amsterdam 1105 AZ, The Netherlands., Koenig W; Deutsches Herzzentrum München, Technische Universität München, Munich 80636, Germany.; 88DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich 80336, Germany.; Institute of Epidemiology and Medical Biometry, University of Ulm, Ulm 89081, Germany., Kumari M; Department of Epidemiology & Public Health, UCL Institute of Epidemiology & Health Care, University College London, London WC1E 7HB, UK.; Institute for Social and Economic Research, University of Essex, Colchester CO4 3SQ, Germany., Kutalik Z; SIB Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.; University Center for Primary Care and Public Health, University of Lausanne, Lausanne 1010, Switzerland., Lawlor DA; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol BS6 2BN, UK.; Population Health Science, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere 33520, Finland., März W; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim 68167, Germany.; 66Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz 8036, Austria.; SYNLAB Academy, SYNALB Holding Deutschland GmbH, Mannheim 68163, Germany., Mather KA; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney 2052, Australia.; Neuroscience Research Australia, Sydney 2031, Australia., Naitza S; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Monserrato (CA) 09042, Italy., Nauck M; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald 17475, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald 17475, Germany., Ohlsson C; Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, Centre for Bone and Arthritis Research (CBAR), University of Gothenburg, Gothenburg 41345, Sweden., Price JF; Usher Institute, University of Edinburgh, Edinburgh EH8 9AG, UK., Raitakari O; Centre for Population Health Research, University of Turku, Turku University Hospital, Turku 20520, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku 20520, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku 20014, Finland., Rice K; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Sachdev PS; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney 2052, Australia.; Neuropsychiatric Institute, Prince of Wales Hospital, Sydney 2031, Australia., Slagboom E; Department of Biomedical Data Sciences, Section of Molecular Epidemiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands.; Max Planck Institute for Biology of Ageing, Cologne 50931, Germany., Sørensen TIA; Novo Nordisk Foundation Center For Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen DK2200, Denmark.; Department of Public Health, Section on Epidemiology, University of Copenhagen, Copenhagen DK1014, Denmark., Spector T; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Stacey D; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Stathopoulou MG; Université de Lorraine, Inserm, IGE-PCV, Nancy 54000, France., Tanaka T; Longitudinal Study Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, MD 21224, USA., Wannamethee SG; Department of Primary Care & Population Health, UCL Institute of Epidemiology & Health Care, University College London, London NW3 2PF, UK., Whincup P; Population Health Research Institute, St George's, University of London, London SW17 0RE, UK., Rotter JI; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Dehghan A; Department of Epidemiology, Erasmus MC, Rotterdam 3000 CA, The Netherlands., Boerwinkle E; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA.; Departments of Epidemiology and Health Services, University of Washington, Seattle, WA 98101, USA., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, The Netherlands., Alizadeh BZ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, The Netherlands.
Publikováno v:
Human molecular genetics [Hum Mol Genet] 2021 Apr 27; Vol. 30 (5), pp. 393-409.
Autor:
Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, MA, 02118, USA. ctliu@bu.edu., Merino J; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA., Rybin D; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, MA, 02118, USA., DiCorpo D; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, MA, 02118, USA., Benke KS; Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA., Bragg-Gresham JL; Kidney Epidemiology and Cost Center, Department of Internal Medicine - Nephrology, University of Michigan, Ann Arbor, MI, 48109, USA., Canouil M; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, 59000, Lille, France., Corre T; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland.; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Grallert H; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Isaacs A; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; CARIM School for Cardiovascular Diseases, Maastricht Centre for Systems Biology (MaCSBio) and Department of Biochemistry, Maastricht University, Maastricht, The Netherlands., Kutalik Z; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Lahti J; Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki, Finland.; Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland., Marullo L; Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy., Marzi C; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Rasmussen-Torvik LJ; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Rocheleau G; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, 59000, Lille, France.; Preventive and Genomic Cardiology, McGill University Health Centre and Research Institute, Montreal, Quebec, Canada.; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Rueedi R; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Scapoli C; Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy., Verweij N; University Medical Center Groningen, Department of Cardiology, University of Groningen, Groningen, The Netherlands., Vogelzangs N; Maastricht University, Department of Epidemiology, Cardiovascular Research Institute Maastricht (CARIM) & Maastricht Centre for Systems Biology (MaCSBio), Maastricht, The Netherlands., Willems SM; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Yengo L; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, 59000, Lille, France., Bakker SJL; University of Groningen, University Medical Center Groningen, Department of Internal Medicine, Groningen, The Netherlands., Beilby J; PathWest Laboratory Medicine of Western Australia, Nedlands WA, 6009, Australia.; School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands WA, 6009, Australia.; Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands WA, Australia., Hui J; PathWest Laboratory Medicine of Western Australia, Nedlands WA, 6009, Australia.; School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands WA, 6009, Australia.; Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands WA, Australia.; School of Population and Global Health, The University of Western Australia, Nedlands WA, 6009, Australia., Kajantie E; National Institute for Health and Welfare, Helsinki, Finland., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Rathmann W; Institute for Biometrics and Epidemiology, German Diabetes Centre, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Auf'm Hennekamp 65, 40225, Düsseldorf, Germany., Balkau B; CESP Centre for Research in Epidemiology and Population Health, Villejuif, France.; Univ. Paris-Saclay, Univ. Paris Sud, UVSQ, UMRS 1018, F-94807, Villejuif, France.; INSERM U1018, CESP, Renal and Cardiovascular Epidemiology, UVSQ-UPS, Villejuif, France., Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa., Eriksson JG; National Institute for Health and Welfare, Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.; Folkhälsan Research Centre, Helsinki, Finland., Florez JC; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, 02115, USA., Froguel P; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, 59000, Lille, France.; Department of Genomics of Common Disease, Imperial College London, London, United Kingdom., Harris T; National Institute on Aging, Laboratory of Epidemiology and Population Sciences in Intramural Research Program, Baltimore, MD, USA., Hung J; Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands WA, Australia.; School of Medicine and Pharmacology, The University of Western Australia, Nedlands WA, 6009, Australia., James AL; Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands WA, Australia.; School of Medicine and Pharmacology, The University of Western Australia, Nedlands WA, 6009, Australia.; Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands WA, 6009, Australia., Kavousi M; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Miljkovic I; Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA., Musk AW; Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands WA, Australia.; School of Population and Global Health, The University of Western Australia, Nedlands WA, 6009, Australia.; School of Medicine and Pharmacology, The University of Western Australia, Nedlands WA, 6009, Australia., Palmer LJ; School of Public Health, University of Adelaide, Adelaide, Australia., Peters A; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München Research Center for Environmental Health, Neuherberg, Germany., Roussel R; INSERM U1138 (équipe 2: Pathophysiology and Therapeutics of Vascular and Renal Diseases Related to Diabetes, Centre de Recherches des Cordeliers), Paris, France.; Univ. Paris 7 Denis Diderot, Sorbonne Paris Cité, France.; AP-HP, DHU FIRE, Department of Endocrinology, Diabetology, Nutrition, and Metabolic Diseases, Bichat Claude Bernard Hospital, Paris, France., van der Harst P; University Medical Center Groningen, Department of Cardiology, University of Groningen, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands., van Duijn CM; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Vollenweider P; Department of Medicine, Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland., Barroso I; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Prokopenko I; Department of Medicine, Imperial College London, London, United Kingdom.; Wellcome Centre for Human genetics, University of Oxford, Oxford, United Kingdom.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom., Dupuis J; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, MA, 02118, USA.; The National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, USA., Meigs JB; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, 02115, USA.; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA., Bouatia-Naji N; INSERM, UMR970 Paris Cardiovascular Research Center (PARCC), Paris, F-75015, France. nabila.bouatia-naji@inserm.fr.; Paris-Descartes University, Sorbonne Paris Cité, Paris, 75006, France. nabila.bouatia-naji@inserm.fr.
Publikováno v:
Scientific reports [Sci Rep] 2019 Jul 01; Vol. 9 (1), pp. 9439. Date of Electronic Publication: 2019 Jul 01.
Autor:
Schierding W; University of Auckland, Auckland, New Zealand.; Gravida: National Centre for Growth and Development, University of Auckland, Auckland, Auckland, New Zealand., Antony J; Department of Pathology, Dunedin School of Medicine, The University of Otago, Dunedin, New Zealand., Karhunen V; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, UK.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., Vääräsmäki M; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, UK.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland.; PEDEGO Research Unit, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland., Franks S; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, UK.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., Elliott P; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, UK., Kajantie E; PEDEGO Research Unit, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.; Chronic Disease Prevention Unit, National Institute for Health and Welfare, Oulu, Finland.; Children's Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Sebert S; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Department of Genomics of Complex Diseases School of Public Health, Imperial College London, London, UK., Blakemore A; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, UK.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., Horsfield JA; Gravida: National Centre for Growth and Development, University of Auckland, Auckland, Auckland, New Zealand.; Department of Pathology, Dunedin School of Medicine, The University of Otago, Dunedin, New Zealand., Järvelin MR; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, UK.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., O'Sullivan JM; University of Auckland, Auckland, New Zealand.; Gravida: National Centre for Growth and Development, University of Auckland, Auckland, Auckland, New Zealand., Cutfield WS; University of Auckland, Auckland, New Zealand.; Gravida: National Centre for Growth and Development, University of Auckland, Auckland, Auckland, New Zealand.
Publikováno v:
Journal of medical genetics [J Med Genet] 2018 Jan; Vol. 55 (1), pp. 55-63. Date of Electronic Publication: 2017 Oct 10.
Autor:
Barban N; Department of Sociology and Nuffield College, University of Oxford, Oxford, UK., Jansen R; Department of Psychiatry, VU University Medical Center, Amsterdam, the Netherlands., de Vlaming R; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands., Vaez A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran., Mandemakers JJ; Sociology of Consumption and Households, Wageningen University Research, Wageningen, the Netherlands., Tropf FC; Department of Sociology and Nuffield College, University of Oxford, Oxford, UK., Shen X; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Wilson JF; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Chasman DI; Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Tragante V; Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands., van der Laan SW; Laboratory of Experimental Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands., Perry JR; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Kong A; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Ahluwalia TS; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center, Gentofte, Denmark.; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Albrecht E; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Yerges-Armstrong L; Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA., Atzmon G; Department of Medicine, Institute for Aging Research and the Diabetes Research Center, Albert Einstein College of Medicine, Bronx, New York, USA.; Department of Genetics, Institute for Aging Research and the Diabetes Research Center, Albert Einstein College of Medicine, Bronx, New York, USA.; Department of Natural Science, University of Haifa, Haifa, Israel., Auro K; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland., Ayers K; Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK., Bakshi A; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., Ben-Avraham D; Department of Genetics, Institute for Aging Research and the Diabetes Research Center, Albert Einstein College of Medicine, Bronx, New York, USA., Berger K; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Bergman A; Departments of Systems and Computational Biology, of Pathology and of Neuroscience, Albert Einstein College of Medicine, Bronx, New York, USA., Bertram L; Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics and of Integrative and Experimental Genomics, University of Lübeck, Lübeck, Germany.; School of Public Health, Faculty of Medicine, Imperial College, London, UK., Bielak LF; Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA., Bjornsdottir G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Bonder MJ; Department of Genetics, Genomics Coordination Center, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Broer L; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Bui M; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Barbieri C; Division of Genetics and Cell Biology, San Raffaele Research Institute, Milan, Italy., Cavadino A; Population, Policy and Practice, UCL Institute of Child Health, London, UK.; Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventative Medicine, Queen Mary University of London, London, UK., Chavarro JE; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Turman C; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Concas MP; Institute of Genetic and Biomedical Research, National Research Council, UOS of Sassari, Sassari, Italy., Cordell HJ; Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK., Davies G; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Eibich P; Health Economics Research Centre, University of Oxford, Oxford, UK., Eriksson N; 23andMe, Inc., Mountain View, California, USA., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Eriksson J; Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Falahi F; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Felix JF; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Fontana MA; Center for Economic and Social Research, University of Southern California, Los Angeles, California, USA., Franke L; Department of Genetics, Genomics Coordination Center, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Gandin I; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Gaskins AJ; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Gunderson EP; Cardiovascular and Metabolic Conditions Section, Division of Research, Kaiser Permanente Northern California, Oakland, California, USA., Guo X; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA., Hayward C; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., He C; Department of Epidemiology, Indiana University Richard M. Fairbanks School of Public Health, Indianapolis, Indiana, USA., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.; Institute of Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria., Huang H; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Joshi PK; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Karlsson R; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Kiechl S; Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria., Kifley A; Centre for Vision Research, Department of Ophthalmology and Westmead Institute for Medical Research, University of Sydney, Westmead, New South Wales, Australia., Kluttig A; Institute of Medical Epidemiology, Biostatistics and Informatics, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany., Kraft P; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Lagou V; Department of Neurosciences, KU Leuven, Leuven, Belgium.; Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.; Translational Immunology Laboratory, VIB, Leuven, Belgium., Lecoeur C; University of Lille, CNRS, Institut Pasteur of Lille, Lille, France., Lahti J; Institute of Behavioral Sciences, University of Helsinki, Helsinki, Finland.; Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki, Finland.; Folkhälsan Research Centre, Helsinki, Finland., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Lind PA; Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Herston Brisbane, Queensland, Australia., Liu T; Center for Lifespan Psychology, Max Planck Institute for Human Development and Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany., Makalic E; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Mamasoula C; Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK., Matteson L; Minnesota Center for Twin and Family Research, Department of Psychology, University of Minnesota, Minneapolis, Minnesota, USA., Mbarek H; Department of Biological Psychology, VU University, Amsterdam, the Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands., McArdle PF; Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA., McMahon G; School of Social and Community Medicine, University of Bristol, Bristol, UK., Meddens SF; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Complex Trait Genetics, VU University, Amsterdam, the Netherlands., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Miller M; Department of Psychology, University of Minnesota, Minneapolis, Minnesota, USA., Missmer SA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Monnereau C; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Myhre R; Department of Genetics and Bioinformatics, Area of Health Data and Digitalization, Institute of Public Health, Oslo, Norway., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA., Nutile T; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Naples, Italy., Kalafati IP; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Porcu E; Istituto di Ricerca Genetica e Biomedica, CMR, Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy.; Dipartimento di Scienze Biomediche, Università di Sassari, Sassari, Italy., Prokopenko I; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, UK.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Rajan KB; Rush University Medical Center, Chicago, Illinois, USA., Rich-Edwards J; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Rietveld CA; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands., Robino A; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Rose LM; Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Rueedi R; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Ryan KA; Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA., Saba Y; Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Graz, Austria., Schmidt D; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Smith JA; Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA., Stolk L; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Streeten E; Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA., Tönjes A; Department of Medicine, University of Leipzig, Leipzig, Germany., Thorleifsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Ulivi S; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Wedenoja J; Department of Public Health, University of Helsinki, Helsinki, Finland., Wellmann J; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Willeit P; Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.; King's British Heart Foundation Centre, King's College London, London, UK.; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Yao J; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA., Yengo L; University of Lille, CNRS, Institut Pasteur of Lille, Lille, France.; Centre for Neurogenetics and Statistical Genomics, University of Queensland, Brisbane, Queensland, Australia., Zhao JH; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Zhao W; Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA., Zhernakova DV; Department of Genetics, Genomics Coordination Center, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Amin N; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Andrews H; Data Coordinating Center, New York State Psychiatric Institute, New York, New York, USA., Balkau B; University of Lille, CNRS, Institut Pasteur of Lille, Lille, France., Barzilai N; Department of Medicine, Institute for Aging Research and the Diabetes Research Center, Albert Einstein College of Medicine, Bronx, New York, USA., Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Biino G; Institute of Molecular Genetics, National Research Council of Italy, Pavia, Italy., Bisgaard H; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Bønnelykke K; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Boomsma DI; Department of Biological Psychology, VU University, Amsterdam, the Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands., Buring JE; Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Cappellani S; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Ciullo M; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Naples, Italy.; IRCCS Neuromed, Pozzilli, Isernia, Italy., Cox SR; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Cucca F; Istituto di Ricerca Genetica e Biomedica, CMR, Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy.; Dipartimento di Scienze Biomediche, Università di Sassari, Sassari, Italy., Toniolo D; Division of Genetics and Cell Biology, San Raffaele Research Institute, Milan, Italy., Davey-Smith G; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., van Duijn CM; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., de Geus EJ; Department of Biological Psychology, VU University, Amsterdam, the Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands., Eriksson JG; Folkhälsan Research Centre, Helsinki, Finland.; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.; Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland.; Vasa Central Hospital, Vasa, Finland., Evans DA; Rush University Medical Center, Chicago, Illinois, USA., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA., Sala CF; Division of Genetics and Cell Biology, San Raffaele Research Institute, Milan, Italy., Froguel P; University of Lille, CNRS, Institut Pasteur of Lille, Lille, France., Gasparini P; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; Division of Experimental Genetics, Sidra, Doha, Qatar., Girotto G; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; Division of Experimental Genetics, Sidra, Doha, Qatar., Grabe HJ; Department of Psychiatry, University Medicine Greifswald, Greifswald, Germany., Greiser KH; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany., Groenen PJ; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Econometric Institute, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands., de Haan HG; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Haerting J; Institute of Medical Epidemiology, Biostatistics and Informatics, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland, USA., Heath AC; Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Heikkilä K; Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland., Hofman A; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Holliday EG; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.; Hunter Medical Research Institute, Newcastle, New South Wales, Australia., Hopper J; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Hyppönen E; Population, Policy and Practice, UCL Institute of Child Health, London, UK.; Centre for Population Health Research, Sansom Institute of Health Research and School of Health Sciences, University of South Australia, Adelaide, South Australia, Australia.; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia., Jacobsson B; Department of Genetics and Bioinformatics, Area of Health Data and Digitalization, Institute of Public Health, Oslo, Norway.; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden., Jaddoe VW; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Johannesson M; Department of Economics, Stockholm School of Economics, Stockholm, Sweden., Jugessur A; Department of Genetics and Bioinformatics, Area of Health Data and Digitalization, Institute of Public Health, Oslo, Norway., Kähönen M; Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere, Finland., Kajantie E; Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.; Children's Hospital, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland.; Department of Obstetrics and Gynecology, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland., Kardia SL; Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA., Keavney B; Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK.; Institute of Cardiovascular Sciences, University of Manchester, Manchester, UK., Kolcic I; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia., Koponen P; Health Monitoring Unit, National Institute for Health and Welfare, Helsinki, Finland., Kovacs P; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany., Kronenberg F; Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria., Kutalik Z; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Institute of Social and Preventive Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland., La Bianca M; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Lachance G; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Iacono WG; Department of Psychology, University of Minnesota, Minneapolis, Minnesota, USA., Lai S; Istituto di Ricerca Genetica e Biomedica, CMR, Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, Tampere, Finland., Liewald DC; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Lindgren CM; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK.; Strangeways Research Laboratory, University of Cambridge, Cambridge, UK., Liu Y; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA., Luben R; Strangeways Research Laboratory, University of Cambridge, Cambridge, UK., Lucht M; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland., Luoto R; UKK Institute for Health Promotion,Tampere, Finland., Magnus P; Department of Genetics and Bioinformatics, Area of Health Data and Digitalization, Institute of Public Health, Oslo, Norway., Magnusson PK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Martin NG; Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Herston Brisbane, Queensland, Australia., McGue M; Department of Psychology, University of Minnesota, Minneapolis, Minnesota, USA.; Danish Aging Research Center and Danish Twin Registry, Institute of Public Health, University of Southern Denmark, Odense, Denmark., McQuillan R; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Medland SE; Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Herston Brisbane, Queensland, Australia., Meisinger C; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; MONICA/KORA Myocardial Infarction Registry, Central Hospital of Augsburg, Augsburg, Germany., Mellström D; Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Traglia M; Division of Genetics and Cell Biology, San Raffaele Research Institute, Milan, Italy., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mitchell P; Centre for Vision Research, Department of Ophthalmology and Westmead Institute for Medical Research, University of Sydney, Westmead, New South Wales, Australia., Montgomery GW; Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Mook-Kanamori D; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.; Department of BESC, Epidemiology Section, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia., de Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Nohr EA; Research Unit for Gynecology and Obstetrics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Ohlsson C; Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Olsen J; Department of Clinical Epidemiology, Aarhus University, Aarhus, Denmark., Ong KK; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Paternoster L; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Pattie A; Department of Psychology, University of Edinburgh, Edinburgh, UK., Penninx BW; Department of Psychiatry, VU University Medical Center, Amsterdam, the Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands., Perola M; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Peyser PA; Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA., Pirastu M; Institute of Genetic and Biomedical Research, National Research Council, UOS of Sassari, Sassari, Italy., Polasek O; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia., Power C; Population, Policy and Practice, UCL Institute of Child Health, London, UK., Kaprio J; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland., Raffel LJ; Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Räikkönen K; Institute of Behavioral Sciences, University of Helsinki, Helsinki, Finland., Raitakari O; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku and Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland., Ridker PM; Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Ring SM; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Roll K; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Ruggiero D; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Naples, Italy., Rujescu D; Department of Psychiatry, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany., Salomaa V; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Schlessinger D; Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, USA., Schmidt H; Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Graz, Austria., Schmidt R; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria., Schupf N; Departments of Epidemiology and Psychiatry, Columbia University Medical Center, New York, New York, USA., Smit J; Department of Psychiatry, VU University Medical Center, Amsterdam, the Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands., Sorice R; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Naples, Italy.; IRCCS Neuromed, Pozzilli, Isernia, Italy., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK., Stöckl D; Departments of Epidemiology and Psychiatry, Columbia University Medical Center, New York, New York, USA., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig Maximilians Universität, Munich, Germany., Stumvoll M; Department of Medicine, University of Leipzig, Leipzig, Germany.; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany., Swertz MA; Department of Genetics, Genomics Coordination Center, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Thorsteinsdottir U; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Thurik AR; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Montpellier Business School, Montpellier, France., Timpson NJ; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Tung JY; 23andMe, Inc., Mountain View, California, USA., Uitterlinden AG; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Vaccargiu S; Institute of Genetic and Biomedical Research, National Research Council, UOS of Sassari, Sassari, Italy., Viikari J; Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland., Vitart V; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Vollenweider P; Department of Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland., Vuckovic D; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; Division of Experimental Genetics, Sidra, Doha, Qatar., Waage J; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Wagner GG; German Socio-Economic Panel Study (SOEP), Max Planck Institute for Human Development and Berlin University of Technology (TUB), Berlin, Germany., Wang JJ; Centre for Vision Research, Department of Ophthalmology and Westmead Institute for Medical Research, University of Sydney, Westmead, New South Wales, Australia., Wareham NJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA., Willemsen G; Department of Biological Psychology, VU University, Amsterdam, the Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands., Willeit J; Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria., Wright AF; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Zondervan KT; Genetic and Genomic Epidemiology Unit, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Endometriosis CaRe Centre, Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK., Stefansson K; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Krueger RF; Department of Psychology, University of Minnesota, Minneapolis, Minnesota, USA., Lee JJ; Department of Psychology, University of Minnesota, Minneapolis, Minnesota, USA., Benjamin DJ; Center for Economic and Social Research, University of Southern California, Los Angeles, California, USA.; National Bureau of Economic Research, Cambridge, Massachusetts, USA., Cesarini D; Department of Economics, New York University, New York, New York, USA.; Research Institute for Industrial Economics, Stockholm, Sweden., Koellinger PD; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Complex Trait Genetics, VU University, Amsterdam, the Netherlands., den Hoed M; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Mills MC; Department of Sociology and Nuffield College, University of Oxford, Oxford, UK.
Publikováno v:
Nature genetics [Nat Genet] 2016 Dec; Vol. 48 (12), pp. 1462-1472. Date of Electronic Publication: 2016 Oct 31.
Autor:
Okbay A; Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands., Baselmans BM; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands., De Neve JE; Saïd Business School, University of Oxford, Oxford, UK., Turley P; Department of Economics, Harvard University, Cambridge, Massachusetts, USA., Nivard MG; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands., Fontana MA; Center for Economic and Social Research, University of Southern California, Los Angeles, California, USA., Meddens SF; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Department of Complex Trait Genetics, Vrije Universiteit, Center for Neurogenomics and Cognitive Research, Amsterdam, the Netherlands.; Amsterdam Business School, University of Amsterdam, Amsterdam, the Netherlands., Linnér RK; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Department of Complex Trait Genetics, Vrije Universiteit, Center for Neurogenomics and Cognitive Research, Amsterdam, the Netherlands.; Amsterdam Business School, University of Amsterdam, Amsterdam, the Netherlands., Rietveld CA; Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands., Derringer J; Department of Psychology, University of Illinois, Champaign, Illinois, USA., Gratten J; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., Lee JJ; Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA., Liu JZ; New York Genome Center, New York, New York, USA., de Vlaming R; Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands., Ahluwalia TS; COPSAC (Copenhagen Prospective Studies on Asthma in Childhood), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark.; Steno Diabetes Center, Gentofte, Denmark., Buchwald J; Department of Public Health, University of Helsinki, Helsinki, Finland., Cavadino A; Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK.; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia., Frazier-Wood AC; USDA-ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas, USA., Furlotte NA; 23andMe, Inc., Mountain View, California, USA., Garfield V; Department of Epidemiology and Public Health, University College London, London, UK., Geisel MH; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Gonzalez JR; Centre for Research in Environmental Epidemiology, Institute for Global Health, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain.; CIBER Epidemiología y Salud Pública, Barcelona, Spain., Haitjema S; Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands., Karlsson R; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., van der Laan SW; Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands., Ladwig KH; Department of Psychosomatic Medicine and Psychotherapy, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany., Lahti J; Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.; Folkhälsan Research Centre, Helsingfors, Finland.; Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki, Finland., van der Lee SJ; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Lind PA; Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Liu T; Max Planck Institute for Human Development, Berlin, Germany.; Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics, Berlin, Germany., Matteson L; Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Miller MB; Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA., Minica CC; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Mook-Kanamori D; Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.; BESC, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Oldmeadow C; Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales, Australia.; Faculty of Health and Medicine, University of Newcastle, Newcastle, New South Wales, Australia., Qian Y; Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, USA., Raitakari O; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Department of Clinical Physiology, Turku University Hospital, Turku, Finland., Rawal R; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Realo A; Department of Psychology, University of Tartu, Tartu, Estonia.; Department of Psychology, University of Warwick, Coventry, UK., Rueedi R; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Schmidt B; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Smith AV; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Stergiakouli E; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Tanaka T; National Institute on Aging, US National Institutes of Health, Baltimore, Maryland, USA., Taylor K; Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor-UCLA, Torrence, California, USA., Thorleifsson G, Wedenoja J; Department of Public Health, University of Helsinki, Helsinki, Finland., Wellmann J; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Westra HJ; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Division of Rheumatology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Willems SM; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Zhao W; Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA., Amin N; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Bakshi A; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., Bergmann S, Bjornsdottir G, Boyle PA; Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois, USA., Cherney S; RAND Corporation, Santa Monica, California, USA., Cox SR; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Davies G; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Davis OS; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Ding J; Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, USA., Direk N; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Eibich P; German Socio-Economic Panel Study, DIW Berlin, Berlin, Germany.; Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Emeny RT; Institute of Epidemiology II, Mental Health Research Unit, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA., Fatemifar G; Farr Institute of Health Informatics, University College London, London, UK., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA., Ferrucci L; National Institute on Aging, US National Institutes of Health, Baltimore, Maryland, USA., Forstner AJ; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Gupta R; Department of Public Health, University of Helsinki, Helsinki, Finland., Harris TB; Laboratory of Epidemiology, Demography, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA., Harris JM; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Holliday EG; Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales, Australia.; Faculty of Health and Medicine, University of Newcastle, Newcastle, New South Wales, Australia., Hottenga JJ; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands., De Jager PL; Program in Translational NeuroPsychiatric Genomics, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Kaakinen MA; Department of Genomics of Common Disease, Imperial College London, London, UK.; Center for Life Course Health Research, University of Oulu and Oulu University Hospital, Oulu, Finland., Kajantie E; Department of Pediatrics, University of Helsinki, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland., Karhunen V; Center for Life Course Health Research, University of Oulu and Oulu University Hospital, Oulu, Finland., Kolcic I; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia., Kumari M; Institute for Social and Economic Research, University of Essex, Wivenhoe Park, UK., Launer LJ; Neuroepidemiology Section, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA., Franke L; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Li-Gao R; Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Liewald DC, Koini M; Department of Neurology, General Hospital and Medical University Graz, Graz, Austria., Loukola A; Department of Public Health, University of Helsinki, Helsinki, Finland., Marques-Vidal P; Department of Internal Medicine, Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland., Montgomery GW; Molecular Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Mosing MA; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden., Paternoster L; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Pattie A; Department of Psychology, University of Edinburgh, Edinburgh, UK., Petrovic KE; Department of Neurology, General Hospital and Medical University Graz, Graz, Austria., Pulkki-Råback L; Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.; Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki, Finland., Quaye L; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Räikkönen K; Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland., Rudan I; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Scott RJ; Faculty of Health and Medicine, University of Newcastle, Newcastle, New South Wales, Australia.; Information-Based Medicine Stream, Hunter Medical Research Institute, New Lambton, New South Wales, Australia., Smith JA; Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA., Sutin AR; National Institute on Aging, US National Institutes of Health, Baltimore, Maryland, USA.; Department of Behavioral Sciences and Social Medicine, Florida State University College of Medicine, Tallahassee, Florida, USA., Trzaskowski M; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia., Vinkhuyzen AE; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., Yu L; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA., Zabaneh D; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia., Attia JR; Public Health Stream, Hunter Medical Research Institute, New Lambton, New South Wales, Australia.; Faculty of Health and Medicine, University of Newcastle, Newcastle, New South Wales, Australia., Bennett DA; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA., Berger K; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Bertram L; Lübeck Interdisciplinary Platform for Genome Analytics (LIGA), Institute of Neurogenetics and Institute of Integrative and Experimental Genomics, University of Lübeck, Lübeck, Germany.; Neuroepidemiology and Ageing Research Unit, School of Public Health, Faculty of Medicine, Imperial College London, London, UK., Boomsma DI; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands.; Neuroscience Campus Amsterdam, Amsterdam, the Netherlands., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Chang SC; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Cucca F; Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cittadella Universitarià di Monserrato, Monserrato, Italy., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., van Duijn CM; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Eriksson JG; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.; Unit of General Practice, University Central Hospital, Helsinki, Finland., Bültmann U; Department of Health Sciences, Community and Occupational Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., de Geus EJ; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands.; Neuroscience Campus Amsterdam, Amsterdam, the Netherlands., Groenen PJ; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Econometric Institute, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark., Hartman CA; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Haworth CM; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Heath AC; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA., Hinds DA; 23andMe, Inc., Mountain View, California, USA., Hyppönen E; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.; Centre for Population Health Research, School of Health Sciences and Sansom Institute, University of South Australia, Adelaide, South Australia, Australia.; Population, Policy and Practice, UCL Institute of Child Health, London, UK., Iacono WG; Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA., Järvelin MR; Department of Genomics of Common Disease, Imperial College London, London, UK.; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., Jöckel KH; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Kaprio J; Department of Public Health, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Department for Health, THL (National Institute for Health and Welfare), Helsinki, Finland., Kardia SL; Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA., Keltikangas-Järvinen L; Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland., Kraft P; Department of Epidemiology and Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Kubzansky LD; Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Lehtimäki T; Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, University of Tampere, School of Medicine, Tampere, Finland., Magnusson PK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Martin NG; Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., McGue M; Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Mills M; Department of Sociology, University of Oxford, Oxford, UK., de Mutsert R; Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Oldehinkel AJ; Econometric Institute, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands., Pasterkamp G; Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.; Laboratory of Clinical Chemistry and Hematology, Division of Laboratories and Pharmacy, University Medical Center Utrecht, Utrecht, the Netherlands., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Plomin R; Social, Genetic and Developmental Psychiatry Centre, King's College London, De Crespigny Park, UK., Polasek O; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia., Power C; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.; Population, Policy and Practice, UCL Institute of Child Health, London, UK., Rich SS; Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, USA., Rosendaal FR; Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., den Ruijter HM; Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands., Schlessinger D; Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, USA., Schmidt H; Department of Neurology, General Hospital and Medical University Graz, Graz, Austria.; Research Unit for Genetic Epidemiology, Institute of Molecular Biology and Biochemistry, Center of Molecular Medicine, General Hospital and Medical University Graz, Graz, Austria., Svento R; Department of Economics, Oulu Business School, Oulu, Finland., Schmidt R; Department of Neurology, General Hospital and Medical University Graz, Graz, Austria., Alizadeh BZ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Sørensen TI; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark.; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospitals, Capital Region, Frederiksberg, Denmark., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Starr JM, Stefansson K, Steptoe A; Department of Epidemiology and Public Health, University College London, London, UK., Terracciano A; National Institute on Aging, US National Institutes of Health, Baltimore, Maryland, USA.; Department of Behavioral Sciences and Social Medicine, Florida State University College of Medicine, Tallahassee, Florida, USA., Thorsteinsdottir U, Thurik AR; Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Montpellier Business School, Montpellier, France.; Panteia, Zoetermeer, the Netherlands., Timpson NJ; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Tiemeier H; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Psychiatry, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Child and Adolescent Psychiatry, Erasmus Medical Center, Rotterdam, the Netherlands., Uitterlinden AG; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Vollenweider P; Department of Internal Medicine, Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland., Wagner GG; Max Planck Institute for Human Development, Berlin, Germany.; German Socio-Economic Panel Study, DIW Berlin, Berlin, Germany.; School of Economics and Management, Berlin University of Technology, Berlin, Germany., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA., Yang J; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia., Conley DC; Department of Sociology, Princeton University, Princeton, New Jersey, USA., Smith GD; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Hofman A; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Johannesson M; Department of Economics, Stockholm School of Economics, Stockholm, Sweden., Laibson DI; Department of Economics, Harvard University, Cambridge, Massachusetts, USA., Medland SE; Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Meyer MN; Department of Bioethics, Clarkson University, Schenectady, New York, USA.; Icahn School of Medicine at Mount Sinai, New York, New York, USA., Pickrell JK; New York Genome Center, New York, New York, USA.; Department of Biological Sciences, Columbia University, New York, New York, USA., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia., Krueger RF; Department of Psychology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA., Beauchamp JP; Department of Economics, Harvard University, Cambridge, Massachusetts, USA., Koellinger PD; Erasmus University Rotterdam Institute for Behavior and Biology, Rotterdam, the Netherlands.; Department of Complex Trait Genetics, Vrije Universiteit, Center for Neurogenomics and Cognitive Research, Amsterdam, the Netherlands.; Amsterdam Business School, University of Amsterdam, Amsterdam, the Netherlands., Benjamin DJ; Center for Economic and Social Research, University of Southern California, Los Angeles, California, USA., Bartels M; Department of Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, the Netherlands.; Neuroscience Campus Amsterdam, Amsterdam, the Netherlands., Cesarini D; Department of Economics, New York University, New York, New York, USA.; Research Institute for Industrial Economics, Stockholm, Sweden.
Publikováno v:
Nature genetics [Nat Genet] 2016 Jun; Vol. 48 (6), pp. 624-33. Date of Electronic Publication: 2016 Apr 18.
Autor:
Kilpeläinen TO; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 1, DIKU Building, Copenhagen 2100, Denmark.; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge CB2 0QQ, UK.; Genetics of Obesity and Related Metabolic Traits Program, Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Carli JF; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York 10032, USA., Skowronski AA; Institute of Human Nutrition, Columbia University, New York, New York 10032, USA., Sun Q; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachussetts 02115, USA.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachussetts 02115, USA., Kriebel J; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg 85764, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg 85764, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg 85764, Germany., Feitosa MF; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110, USA., Hedman ÅK; Science for Life Laboratory, Uppsala University, Uppsala 750 85, Sweden.; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 751 85, Sweden.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Drong AW; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Hayes JE; Cell and Developmental Biology Graduate Program, Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, New York 10021, USA.; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Zhao J; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge CB2 0QQ, UK., Pers TH; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 1, DIKU Building, Copenhagen 2100, Denmark.; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachussetts 02115, USA.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 2142, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen 2300, Denmark., Schick U; Genetics of Obesity and Related Metabolic Traits Program, Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Grarup N; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 1, DIKU Building, Copenhagen 2100, Denmark., Kutalik Z; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne 1010, Switzerland.; Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden 2333, The Netherlands.; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden 2333, The Netherlands., Mangino M; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.; National Institute for Health Research Biomedical Research Centre at Guy's and St. Thomas' Foundation Trust, London SE1 9RT, UK., Kristiansson K; Department of Health, National Institute for Health and Welfare, Helsinki FI-00271, Finland.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki FI-00290, Finland., Beekman M; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere FI-33101, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere FI-33014, Finland., Eriksson J; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden., Henneman P; Department of Human Genetics, Leiden University Medical Center, Leiden 2333, The Netherlands.; Department of Clinical Genetics, Amsterdam Medical Center, Amsterdam 1081 HV, The Netherlands., Lahti J; Institute of Behavioural Sciences, University of Helsinki, Helsinki FI-00014, Finland.; Folkhälsan Research Center, Helsinki FI-00290, Finland., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA., Luan J; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge CB2 0QQ, UK., Del Greco M F; Center for Biomedicine, European Academy Bozen/Bolzano (EURAC) - Affiliated Institute of the University of Lübeck, Bolzano 39100, Italy., Pasko D; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX2 5DW, UK., Renström F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö 20502, Sweden.; Department of Biobank Research, Umeå University, Umeå 90187, Sweden., Willems SM; Department of Epidemiology, Erasmus MC, Rotterdam 3015 GE, The Netherlands., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachussetts 02215, USA., Guo X; Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Institute for Translational Genomics and Population Sciences, Torrance, California 90502, USA., Liu Y; Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA., Kleber ME; Medical Faculty Mannheim, Vth Department of Medicine, Heidelberg University, Mannheim 68167, Germany., Pérusse L; Department of Kinesiology, Laval University, Quebec City, Quebec, Canada G1V 0A6.; Institute of Nutrition and Functional Foods, Quebec City, Quebec, Canada G1V 0A6., Gaunt T; MRC Integrative Epidemiology Unit and School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UK., Ahluwalia TS; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 1, DIKU Building, Copenhagen 2100, Denmark.; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Ledreborg Allé, Copenhagen DK-2820, Denmark.; Steno Diabetes Center, Gentofte DK-2820, Denmark., Ju Sung Y; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri 63108, USA.; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110, USA., Ramos YF; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands., Amin N; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, Rotterdam 3015 GE, The Netherlands., Amuzu A; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK., Barroso I; Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.; NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.; The University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Bellis C; Human Genetics, Genome Institute of Singapore, Agency for Science, Technology and Research of Singapore, Singapore 138672, Singapore.; Genomics Research Centre, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland 4001, Australia.; Texas Biomedical Research Institute, San Antonio, Texas 78245, USA., Blangero J; Texas Biomedical Research Institute, San Antonio, Texas 78245, USA., Buckley BM; Department of Pharmacology and Therapeutics, University College Cork, Cork T12 YT57, Ireland., Böhringer S; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands., I Chen YD; Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Institute for Translational Genomics and Population Sciences, Torrance, California 90502, USA., de Craen AJ; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden 2333, The Netherlands., Crosslin DR; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, Washington 98195, USA.; Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA., Dale CE; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK., Dastani Z; Department of Human Genetics, McGill University, Montreal, Quebec, Canada H3A 0G4., Day FR; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge CB2 0QQ, UK., Deelen J; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands., Delgado GE; Medical Faculty Mannheim, Vth Department of Medicine, Heidelberg University, Mannheim 68167, Germany., Demirkan A; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, Rotterdam 3015 GE, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden 2333, The Netherlands., Finucane FM; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge CB2 0QQ, UK., Ford I; Robertson Center for Biostatistics, University of Glasgow, Glasgow G12 8QQ, UK., Garcia ME; National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland 2089, USA., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg 85764, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg 85764, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany., Gustafsson S; Science for Life Laboratory, Uppsala University, Uppsala 750 85, Sweden.; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 751 85, Sweden., Hallmans G; Department of Biobank Research, Umeå University, Umeå 90187, Sweden., Hankinson SE; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachussetts 02115, USA.; Department of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, Massachusetts 01003, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA., Havulinna AS; Department of Health, National Institute for Health and Welfare, Helsinki FI-00271, Finland., Herder C; German Center for Diabetes Research (DZD), München-Neuherberg 85764, Germany.; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf 40225, Germany., Hernandez D; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland 20892, USA., Hicks AA; Center for Biomedicine, European Academy Bozen/Bolzano (EURAC) - Affiliated Institute of the University of Lübeck, Bolzano 39100, Italy., Hunter DJ; Department of Nutrition and Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA., Illig T; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg 85764, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover 30625, Germany.; Institute for Human Genetics, Hannover Medical School, Hannover 30625, Germany., Ingelsson E; Science for Life Laboratory, Uppsala University, Uppsala 750 85, Sweden.; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 751 85, Sweden.; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA., Ioan-Facsinay A; Department of Rheumatology, Leiden University Medical Center, Leiden 2333, The Netherlands., Jansson JO; Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg 41345, Sweden., Jenny NS; Laboratory for Clinical Biochemistry Research, Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Colchester, Vermont 05405, USA., Jørgensen ME; Steno Diabetes Center, Gentofte DK-2820, Denmark., Jørgensen T; Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup 2600, Denmark.; Faculty of Medicine, University of Aalborg, Aalborg 9100, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark., Karlsson M; Clinical and Molecular Osteoporosis Research Unit, Department of Clinical Sciences and Orthopaedic Surgery, Lund University, Skåne University Hospital, Malmö 21428, Sweden., Koenig W; Department of Internal Medicine II - Cardiology, University of Ulm, Ulm 89081, Germany.; Deutsches Herzzentrum München, Technische Universität München, Munich 80636, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich 80539, Germany., Kraft P; Department of Epidemiology and Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachussetts 02115, USA., Kwekkeboom J; Department of Rheumatology, Leiden University Medical Center, Leiden 2333, The Netherlands., Laatikainen T; Department of Health, National Institute for Health and Welfare, Helsinki FI-00271, Finland.; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio FI-70211, Finland.; Hospital District of North Karelia, Joensuu FI-80210, Finland., Ladwig KH; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg 85764, Germany.; Department of Psychosomatic Medicine and Psychotherapy, Klinikum Rechts der Isar, Technische Universität München, Munich 81675, Germany., LeDuc CA; Division of Molecular Genetics, Department of Pediatrics, Columbia University, New York, New York 10029, USA., Lowe G; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8QQ, UK., Lu Y; Genetics of Obesity and Related Metabolic Traits Program, Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Marques-Vidal P; Department of Internal Medicine, Lausanne University Hospital, Lausanne 1011, Switzerland., Meisinger C; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg 85764, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg 85764, Germany., Menni C; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Department of Biostatistics, University of Liverpool, Liverpool L69 3GA, UK., Myers RH; Department of Neurology, Boston University School of Medicine, Boston, Massachussetts 02118, USA., Männistö S; Department of Health, National Institute for Health and Welfare, Helsinki FI-00271, Finland., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland 20892, USA., Paternoster L; MRC Integrative Epidemiology Unit and School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UK., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg 85764, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg 85764, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich 80539, Germany., Pradhan AD; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachussetts 02215, USA.; Harvard Medical School, Boston, Massachussetts 02115, USA., Rankinen T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA., Rasmussen-Torvik LJ; Preventive Medicine, Northwestern Feinberg School of Medicine, Chicago, Illinois 60611, USA., Rathmann W; Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf 40225, Germany., Rice TK; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri 63108, USA.; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110, USA., Brent Richards J; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.; Department of Medicine, Human Genetics and Epidemiology, McGill University, Montreal, Quebec, Canada H3A 0G4., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachussetts 02215, USA.; Harvard Medical School, Boston, Massachussetts 02115, USA., Sattar N; Faculty of Medicine, BHF Glasgow Cardiovascular Research Centre, Glasgow G12 8QQ, UK., Savage DB; The University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Söderberg S; Department of Public Health and Clinical Medicine, Cardiology and Heart Centre, Umeå University, Umeå 90187, Sweden., Timpson NJ; MRC Integrative Epidemiology Unit and School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UK., Vandenput L; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden., van Heemst D; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden 2333, The Netherlands., Uh HW; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands., Vohl MC; Institute of Nutrition and Functional Foods, Quebec City, Quebec, Canada G1V 0A6.; School of Nutrition, Laval University, Quebec City, Quebec, Canada G1V 0A6., Walker M; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE1 7RU, UK., Wichmann HE; Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität and Klinikum Grosshadern, Munich 80336, Germany.; Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg 85764, Germany.; Institute of Medical Statistics and Epidemiology, Technical University Munich, Munich 81675, Germany., Widén E; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki FI-00290, Finland., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX2 5DW, UK., Yao J; Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Institute for Translational Genomics and Population Sciences, Torrance, California 90502, USA., Zeller T; German Center for Cardiovascular Research (DZHK e.V.), partner site Hamburg/Kiel/Lübeck, Hamburg 20246, Germany.; Clinic for General and Interventional Cardiology, University Heart Center Hamburg, Hamburg 20246, Germany., Zhang Y; Division of Molecular Genetics, Department of Pediatrics, Columbia University, New York, New York 10029, USA., Meulenbelt I; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands., Kloppenburg M; Department of Rheumatology, Leiden University Medical Center, Leiden 2333, The Netherlands.; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden 2333, The Netherlands., Astrup A; Faculty of Science, Department of Nutrition, Exercise, and Sports, University of Copenhagen, Copenhagen 1165, Denmark., Sørensen TI; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 1, DIKU Building, Copenhagen 2100, Denmark.; MRC Integrative Epidemiology Unit and School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UK.; Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospitals, The Capital Region, Copenhagen 2000, Denmark., Sarzynski MA; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA., Rao DC; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri 63108, USA.; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110, USA., Jousilahti P; Department of Health, National Institute for Health and Welfare, Helsinki FI-00271, Finland., Vartiainen E; Department of Health, National Institute for Health and Welfare, Helsinki FI-00271, Finland., Hofman A; Department of Epidemiology, Erasmus MC, Rotterdam 3015 GE, The Netherlands., Rivadeneira F; Department of Epidemiology, Erasmus MC, Rotterdam 3015 GE, The Netherlands.; Department of Internal Medicine, Erasmus MC, Rotterdam 3015 GE, The Netherlands., Uitterlinden AG; Department of Epidemiology, Erasmus MC, Rotterdam 3015 GE, The Netherlands.; Department of Internal Medicine, Erasmus MC, Rotterdam 3015 GE, The Netherlands., Kajantie E; Department of Health, National Institute for Health and Welfare, Helsinki FI-00271, Finland.; Children's Hospital, Helsinki University Central Hospital and University of Helsinki, Helsinki FI-00014, Finland.; Department of Obstetrics and Gynaecology, MRC Oulu, Oulu University Central Hospital and University of Oulu, Oulu 90220, Finland., Osmond C; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK., Palotie A; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki FI-00290, Finland.; Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.; Center for Human Genetic Research, Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Eriksson JG; Department of Health, National Institute for Health and Welfare, Helsinki FI-00271, Finland.; Folkhälsan Research Center, Helsinki FI-00290, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki FI-00014, Finland., Heliövaara M; Department of Health, National Institute for Health and Welfare, Helsinki FI-00271, Finland., Knekt PB; Department of Health, National Institute for Health and Welfare, Helsinki FI-00271, Finland., Koskinen S; Department of Health, National Institute for Health and Welfare, Helsinki FI-00271, Finland., Jula A; Department of Health, National Institute for Health and Welfare, Helsinki FI-00271, Finland., Perola M; Department of Health, National Institute for Health and Welfare, Helsinki FI-00271, Finland.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki FI-00290, Finland.; University of Tartu, Estonian Genome Centre, Tartu 51010, Estonia., Huupponen RK; Department of Pharmacology, Drug Development and Therapeutics, University of Turku, Turku FI-20520, Finland.; Unit of Clinical Pharmacology, Turku University Hospital, Turku FI-20520, Finland., Viikari JS; Division of Medicine, Turku University Hospital, Turku FI-20520, Finland.; Department of Medicine, University of Turku, Turku FI-20520, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere FI-33521, Finland.; Department of Clinical Physiology, University of Tampere School of Medicine, Tampere FI-33014, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere FI-33101, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere FI-33014, Finland., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku FI-2051, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku FI-20520, Finland., Mellström D; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden., Lorentzon M; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden., Casas JP; Farr Institute of Health Informatics, University College London, London NW1 2DA, UK., Bandinelli S; Geriatric Unit, Azienda Sanitaria Firenze, Florence 50122, Italy., März W; Medical Faculty Mannheim, Vth Department of Medicine, Heidelberg University, Mannheim 68167, Germany.; Synlab Academy, Synlab Services LLC, Mannheim 68161, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz 8010, Austria., Isaacs A; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, Rotterdam 3015 GE, The Netherlands., van Dijk KW; Department of Human Genetics, Leiden University Medical Center, Leiden 2333, The Netherlands., van Duijn CM; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, Rotterdam 3015 GE, The Netherlands.; Center of Medical Systems Biology, Leiden 2300 RC, The Netherlands., Harris TB; Laboratory of Epidemiology and Population Science, National Institute on Aging, Bethesda, Maryland 20892, USA., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA., Allison MA; Family and Preventive Medicine, University of California-San Diego, La Jolla, California 92161, USA., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachussetts 02215, USA.; Harvard Medical School, Boston, Massachussetts 02115, USA., Ohlsson C; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala 75185, Sweden., Scott RA; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge CB2 0QQ, UK., Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge CB2 0QQ, UK., Wareham NJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge CB2 0QQ, UK., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX2 5DW, UK., Pramstaller PP; Center for Biomedicine, European Academy Bozen/Bolzano (EURAC) - Affiliated Institute of the University of Lübeck, Bolzano 39100, Italy.; Department of Neurology, General Central Hospital, Bolzano 39100, Italy.; Department of Neurology, University of Lübeck, Lübeck 23562, Germany., Borecki IB; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110, USA., Waterworth DM; GlaxoSmithKline, King of Prussia, Pennsylvania 19406, USA., Bergmann S; Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.; Department of Medical Genetics, University of Lausanne, Lausanne 1015, Switzerland., Waeber G; Department of Internal Medicine, Lausanne University Hospital, Lausanne 1011, Switzerland., Vollenweider P; Department of Internal Medicine, Lausanne University Hospital, Lausanne 1011, Switzerland., Vestergaard H; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 1, DIKU Building, Copenhagen 2100, Denmark.; Steno Diabetes Center, Gentofte DK-2820, Denmark., Hansen T; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 1, DIKU Building, Copenhagen 2100, Denmark.; Faculty of Health Sciences, University of Southern Denmark, Odense 5230, Denmark., Pedersen O; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 1, DIKU Building, Copenhagen 2100, Denmark., Hu FB; Department of Nutrition and Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA., Eline Slagboom P; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands., Grallert H; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg 85764, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg 85764, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg 85764, Germany., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden 2333, The Netherlands.; Interuniversity Cardiology Institute of the Netherlands, Utrecht 3511 EP, The Netherlands.; Durrer Center for Cardiogenetic Research, Amsterdam 1105 AZ, The Netherlands., Klein RJ; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Schadt EE; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Franks PW; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachussetts 02115, USA.; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö 20502, Sweden.; Department of Public Health and Clinical Medicine, Umeå University, Umeå 90187, Sweden., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachussetts 02142, USA.; The Big Data Institute, University of Oxford, Oxford OX1 2JD, UK., Leibel RL; Division of Molecular Genetics, Department of Pediatrics, Columbia University, New York, New York 10029, USA., Loos RJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge CB2 0QQ, UK.; Genetics of Obesity and Related Metabolic Traits Program, Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Publikováno v:
Nature communications [Nat Commun] 2016 Feb 01; Vol. 7, pp. 10494. Date of Electronic Publication: 2016 Feb 01.
Autor:
Winkler TW; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany., Justice AE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Graff M; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Barata L; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Chu S; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America., Czajkowski J; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Esko T; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America., Fall T; Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden., Kilpeläinen TO; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom., Lu Y; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Mägi R; Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Mihailov E; Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia., Pers TH; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America., Rüeger S; Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Social and Preventive Medicine, University Hospital Lausanne (CHUV), Lausanne, Switzerland., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Ehret GB; Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva, Switzerland; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America., Ferreira T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Heard-Costa NL; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America., Karjalainen J; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands., Lagou V; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Neinast MD; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America., Prokopenko I; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Hammersmith Hospital, London, United Kingdom; Department of Genomics of Common Diseases, School of Public Health, Imperial College London, London, United Kingdom., Simino J; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Teslovich TM; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America., Jansen R; Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands., Westra HJ; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Divisions of Genetics and Rheumatology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Partners Center for Personalized Genetic Medicine, Boston, Massachusetts, United States of America., White CC; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America., Absher D; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America., Ahluwalia TS; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Steno Diabetes Center A/S, Gentofte, Denmark; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Ahmad S; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden., Albrecht E; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Alves AC; Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College, London, United Kingdom., Bragg-Gresham JL; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America., de Craen AJ; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands., Bis JC; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America., Bonnefond A; CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France., Boucher G; Montreal Heart Institute, Montréal, Québec, Canada., Cadby G; Centre for Genetic Origins of Health and Disease, University of Western Australia, Crawley, Western Australia, Australia., Cheng YC; VA Maryland Health Care System, Baltimore, Maryland, United States of America; University of Maryland School of Medicine, Department of Medicine, Baltimore, Maryland, United States of America., Chiang CW; Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, California, United States of America., Delgado G; Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany., Demirkan A; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Dueker N; Universiy of Maryland School of Medicine, Department of Epidemiology & Public Health, Baltimore, Maryland, United States of America., Eklund N; National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Eiriksdottir G; Icelandic Heart Association, Kopavogur, Iceland., Eriksson J; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Feenstra B; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Fischer K; Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia., Frau F; Department of Health Sciences, University of Milan, Milan, Italy; Filarete Foundation, Genomic and Bioinformatics Unit, Milano, Italy., Galesloot TE; Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands., Geller F; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Goel A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom., Gorski M; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Grammer TB; Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany., Gustafsson S; Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden., Haitjema S; Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands., Hottenga JJ; Department of Biological Psychology, VU University, Amsterdam, The Netherlands., Huffman JE; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Jackson AU; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America., Jacobs KB; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America., Johansson Å; Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Kaakinen M; Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College, London, United Kingdom; Institute of Health Sciences, University of Oulu, Oulu, Finland., Kleber ME; Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany., Lahti J; Folkhälsan Research Centre, Helsinki, Finland; Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland., Mateo Leach I; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands., Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom., Liu Y; Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina, United States of America., Lo KS; Montreal Heart Institute, Montréal, Québec, Canada., Lorentzon M; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Luan J; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom., Madden PA; Washington University Medical School, St. Louis, Missouri, United States of America., Mangino M; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom., McKnight B; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Program in Biostatistics and Biomathematics, Divison of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America., Medina-Gomez C; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Monda KL; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America; The Center for Observational Research, Amgen Inc., Thousand Oaks, California, United States of America., Montasser ME; Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America., Müller G; Center for Evidence Based Healthcare, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany; DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany., Nolte IM; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands., Panoutsopoulou K; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom., Pascoe L; Institute of Cell & Molecular Biosciences, Newcastle University, Newcastle, United Kingdom., Paternoster L; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom., Rayner NW; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom., Renström F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden., Rizzi F; Department of Health Sciences, University of Milan, Milan, Italy; Filarete Foundation, Genomic and Bioinformatics Unit, Milano, Italy., Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America., Ryan KA; Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America., Salo P; National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland., Sanna S; Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy., Scharnagl H; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria., Shi J; National Cancer Institute, Bethesda, Maryland, United States of America., Smith AV; Icelandic Heart Association, Kopavogur, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Southam L; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom., Stančáková A; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Steinthorsdottir V; deCODE Genetics, Amgen inc., Reykjavik, Iceland., Strawbridge RJ; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Sung YJ; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Tachmazidou I; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, United States of America., Thorleifsson G; deCODE Genetics, Amgen inc., Reykjavik, Iceland., Trompet S; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands., Pervjakova N; Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; National Institute for Health and Welfare, Public Health Genomics Unit, Helsinki, Finland; Institute of Cell and Molecular Biology, Department of Biotechnology, University of Tartu, Tartu, Estonia; University of Helsinki, Helsinki, Finland., Tyrer JP; Department of Oncology, University of Cambridge, Cambridge, United Kingdom., Vandenput L; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., van der Laan SW; Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands., van der Velde N; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Section of Geriatric Medicine, Academic Medical Center, Amsterdam, The Netherlands., van Setten J; Department of Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands., van Vliet-Ostaptchouk JV; University of Groningen, University Medical Center Groningen, Department of Endocrinology, Groningen, The Netherlands., Verweij N; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands., Vlachopoulou E; Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki, Finland., Waite LL; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America., Wang SR; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, United States of America; Divisions of Genetics and Endocrinology and Program in Genomics, Boston's Children's Hospital, Boston, Massachusetts, United States of America., Wang Z; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America., Wild SH; Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland., Willenborg C; DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck, Germany., Wilson JF; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland., Wong A; MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom., Yang J; Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia., Yengo L; CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France., Yerges-Armstrong LM; Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America., Yu L; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom., Zhao JH; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom., Andersson EA; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bakker SJ; University of Groningen, University Medical Center Groningen, Department of Medicine, Groningen, Netherlands., Baldassarre D; Centro Cardiologico Monzino, IRCCS, Milan, Italy; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy., Banasik K; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Barcella M; Department of Health Sciences, University of Milan, Milan, Italy., Barlassina C; Department of Health Sciences, University of Milan, Milan, Italy., Bellis C; Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, United States of America; Genomics Research Centre, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia., Benaglio P; Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland., Blangero J; Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, United States of America., Blüher M; University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany; University of Leipzig, Department of Medicine, Leipzig, Germany., Bonnet F; University Rennes 1, Rennes, France., Bonnycastle LL; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America., Boyd HA; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Bruinenberg M; University of Groningen, University Medical Center Groningen, The LifeLines Cohort Study, Groningen, The Netherlands., Buchman AS; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America., Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland., Chen YD; Los Angeles BioMedical Resesarch Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America., Chines PS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America., Claudi-Boehm S; Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany., Cole J; VA Maryland Health Care System, Baltimore, Maryland, United States of America; Universiy of Maryland School of Medicine, Department of Neurology, Baltimore, Maryland, United States of America., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America., de Geus EJ; Department of Biological Psychology, VU University, Amsterdam, The Netherlands; EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands., de Groot LC; Department of Human Nutrition, Wageningen University, Wageningen, The Netherlands., Dimitriou M; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; Department of Dietetics-Nutrition, Harokopio University, Athens, Greece., Duan J; NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois, United States of America., Enroth S; Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Eury E; CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Forouhi NG; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom., Friedrich N; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Gejman PV; NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois, United States of America., Gigante B; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Glorioso N; Hypertension and Related Disease Centre, AOU-University of Sassari, Sassari, Italy., Go AS; Kaiser Permanente, Division of Research, Oakland, California, United States of America., Gottesman O; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Gräßler J; Department of Medicine III, Pathobiochemistry, University of Dresden, Dresden, Germany., Grallert H; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Gu YM; Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium., Broer L; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Ham AC; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland, United States of America; National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America., Hartman CA; University of Groningen, University Medical Center Groningen, Department of Psychiatry, Groningen, The Netherlands., Hassinen M; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Hastie N; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Hattersley AT; Institue of Biomedical & Clinical Science, University of Exeter, Exeter, United Kingdom., Heath AC; Washington University Medical School, St. Louis, Missouri, United States of America., Henders AK; QIMR Bergofer Medical Research Institute, Brisbane, Queensland, Australia., Hernandez D; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America., Hillege H; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands., Holmen O; Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway., Hovingh KG; Department Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands., Hui J; Pathwest Laboratory Medicine of Western Australia, Nedlands, Western Australia,Australia; School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia, Australia; School of Population Health, University of Western Australia, Nedlands, Western Australia, Australia., Husemoen LL; Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark., Hutri-Kähönen N; Department of Pediatrics, University of Tampere School of Medicine, Tampere, Finland; Department of Pediatrics,Tampere University Hospital, Tampere, Finland., Hysi PG; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom., Illig T; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany; Institute of Human Genetics, Hannover Medical School, Hanover, Germany., De Jager PL; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America; Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts,United States of America., Jalilzadeh S; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom., Jørgensen T; Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Medicine, University of Aalborg, Aalborg, Denmark., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands., Juonala M; Division of Medicine, Turku University Hospital, Turku, Finland; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Medicine, University of Turku, Turku, Finland., Kanoni S; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom., Karaleftheri M; Echinos Medical Centre, Echinos, Greece., Khaw KT; Clinical Gerontology Unit, Addenbrooke's Hospital, Cambridge, United Kingdom., Kinnunen L; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Kittner SJ; VA Maryland Health Care System, Baltimore, Maryland, United States of America; Universiy of Maryland School of Medicine, Department of Neurology, Baltimore, Maryland, United States of America., Koenig W; Department of Internal Medicine II-Cardiology, University of Ulm Medical Center, Ulm, Germany., Kolcic I; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia., Kovacs P; University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany., Krarup NT; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kratzer W; Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany., Krüger J; Department of Medicine A, University Medicine Greifswald, Greifswald, Germany., Kuh D; MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom., Kumari M; Department of Epidemiology and Public Health, UCL, London, United Kingdom., Kyriakou T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom., Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; Department of Epidemiology and Public Health, UCL, London, United Kingdom., Lannfelt L; Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, Sweden., Lanzani C; Chair of Nephrology, Università Vita Salute San Raffaele, Segrate (Milan), Italy; Genomics of Renal Disease and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Segrate (Milan), Italy., Lotay V; Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada., Launer LJ; National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America., Leander K; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Lindström J; Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland., Linneberg A; Research Centre for Prevention and Health, Glostrup Hospital, Glostrup, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Experimental Research, Rigshospitalet, Glostrup, Denmark., Liu YP; Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium., Lobbens S; CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France., Luben R; Strangeways Research Laboratory Wort's Causeway, Cambridge, United Kingdom., Lyssenko V; Steno Diabetes Center A/S, Gentofte, Denmark; Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö, Sweden., Männistö S; National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland., Magnusson PK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., McArdle WL; School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom., Menni C; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom., Merger S; Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany., Milani L; Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia., Montgomery GW; QIMR Bergofer Medical Research Institute, Brisbane, Queensland, Australia., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom., Narisu N; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America., Nelis M; Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia., Ong KK; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom; Department of Paediatrics, University of Cambridge, Cambridge, United Kingdom., Palotie A; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; Massachusetts General Hospital, Center for Human Genetic Research, Psychiatric and Neurodevelopmental Genetics Unit, Boston, Massachusetts, United States of America., Pérusse L; Department of Kinesiology, Laval University, Québec City, Québec, Canada; Institute of Nutrition and Functional Foods, Laval University, Québec City, Québec, Canada., Pichler I; Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany., Pilia MG; Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy., Pouta A; Department of Children, Young People and Families, National Institute for Health and Welfare, Helsinki, Finland; Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland., Rheinberger M; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Ribel-Madsen R; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Richards M; MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom., Rice KM; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America., Rice TK; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America., Rivolta C; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland., Salomaa V; National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland., Sanders AR; NorthShore University HealthSystem, Evanston, Illinois, United States of America; University of Chicago, Chicago, Illinois, United States of America., Sarzynski MA; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America., Scholtens S; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands., Scott RA; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom., Scott WR; Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom., Sebert S; Institute of Health Sciences, University of Oulu, Oulu, Finland., Sengupta S; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America., Sennblad B; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden., Seufferlein T; Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany., Silveira A; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Slagboom PE; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Smit JH; Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands., Sparsø TH; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Stirrups K; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom., Stolk RP; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands., Stringham HM; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America., Swertz MA; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands., Swift AJ; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America., Syvänen AC; Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Tan ST; Ealing Hospital NHS Trust, Middlesex, United Kingdom; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Thorand B; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany., Tönjes A; University of Leipzig, Department of Medicine, Leipzig, Germany., Tremblay A; Department of Kinesiology, Laval University, Québec City, Québec, Canada., Tsafantakis E; Anogia Medical Centre, Anogia, Greece., van der Most PJ; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands., Völker U; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Vohl MC; Institute of Nutrition and Functional Foods, Laval University, Québec City, Québec, Canada; School of Nutrition, Laval University, Québec City, Québec,Canada., Vonk JM; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands., Waldenberger M; DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Walker RW; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Wennauer R; Department of Clinical Chemistry, Ulm University Medical Centre, Ulm, Germany., Widén E; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Willemsen G; Department of Biological Psychology, VU University, Amsterdam, The Netherlands., Wilsgaard T; Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway., Wright AF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Zillikens MC; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., van Dijk SC; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., van Schoor NM; EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands; VUMC, Department of Epidemiology and Biostatistics, Amsterdam, The Netherlands., Asselbergs FW; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, Netherlands; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, The Netherlands; Institute of Cardiovascular Science, University College London, London, United Kingdom., de Bakker PI; Department of Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands; Department of Epidemiology, University Medical Center, Utrecht, The Netherlands., Beckmann JS; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Beilby J; Pathwest Laboratory Medicine of Western Australia, Nedlands, Western Australia,Australia; School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia, Australia., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America., Bergman RN; Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America., Bergmann S; Swiss Institute of Bioinformatics, Lausanne, Switzerland; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland., Böger CA; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Boehm BO; Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany; Imperial College London, London, United Kingdom; Lee Kong Chian School of Medicine, Singapore, Singapore; Nanyang Technological University, Singapore, Singapore., Boerwinkle E; Human Genetics Center and Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas, United States of America., Boomsma DI; Department of Biological Psychology, VU University, Amsterdam, The Netherlands., Bornstein SR; Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; Ealing Hospital NHS Trust, Middlesex, United Kingdom; Imperial College Healthcare NHS Trust, London, United Kingdom., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Program in Biostatistics and Biomathematics, Divison of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America., Cucca F; Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy; University of Sassari, Sassari, Italy., Cusi D; Department of Health Sciences, University of Milan, Milan, Italy; Institute of Biomedical Technologies, National Institute of Research, Segrate-Milano, Italy., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Erdmann J; DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck, Germany., Eriksson JG; National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; Folkhälsan Research Centre, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland., Evans DA; Rush Institute for Healthy Aging and Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States of America., de Faire U; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Farrall M; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, United States of America., Ford I; Robertson Center for Biostatistics, University of Glasgow, Glasgow, United Kingdom., Franke L; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden; Department of Public Health & Clinical Medicine, Umeå University Hospital, Umeå, Sweden, Umeå, Sweden; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America., Froguel P; CNRS UMR 8199, Lille, France; European Genomic Institute for Diabetes, Lille, France; Université de Lille 2, Lille, France., Gansevoort RT; University of Groningen, University Medical Center Groningen, Department of Medicine, Groningen, Netherlands., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Grönberg H; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Gyllensten U; Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Hamsten A; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Department of Medicine, Karolinska Institutet, Stockholm, Sweden., van der Harst P; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, The Netherlands., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Heliövaara M; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Hengstenberg C; DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Deutsches Herzzentrum München, Technische Universität München, München, Germany., Hicks AA; Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany., Hingorani A; Institute of Cardiovascular Science, University College London, London, United Kingdom., Hofman A; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Hu F; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America., Huikuri HV; Medical Research Center Oulu, Oulu University Hospital, and University of Oulu, Oulu, Finland., Hveem K; Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway., James AL; Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia., Jordan JM; Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina, United States of America., Jula A; National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland; Department of Clinical Physiology, University of Tampere School of Medicine, Tampere, Finland., Kajantie E; Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Children's Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Kathiresan S; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Center for Human Genetics Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America., Kiemeney LA; Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands; Radboud university medical center, Radboud Institute for Health Sciences, Department of Urology, Nijmegen, The Netherlands., Kivimaki M; Department of Epidemiology and Public Health, UCL, London, United Kingdom., Knekt PB; National Institute for Health and Welfare, Helsinki, Finland., Koistinen HA; National Institute for Health and Welfare, Helsinki, Finland; University of Helsinki and Helsinki University Central Hospital, Department of Medicine and Abdominal Center: Endocrinology, Helsinki, Finland; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Kooner JS; Ealing Hospital NHS Trust, Middlesex, United Kingdom; National Heart and Lung Institute, Imperial College London, London, United Kingdom; Imperial College Healthcare NHS Trust, London, United Kingdom., Koskinen S; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Kuusisto J; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Maerz W; Vth Department of Medicine, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria., Martin NG; QIMR Bergofer Medical Research Institute, Brisbane, Queensland, Australia., Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lakka TA; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland; Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland., Lehtimäki T; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, Tampere, Finland., Lettre G; Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec, Canada., Levinson DF; Stanford University, Stanford, California, United States of America., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Lokki ML; Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki, Finland., Mäntyselkä P; Primary Health Care Unit, Institute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Kuopio, Finland; Primary Health Care Unit, Kuopio University Hospital, Kuopio, Finland., Melbye M; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America., Metspalu A; Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia., Mitchell BD; University of Maryland School of Medicine, Department of Medicine, Baltimore, Maryland, United States of America; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland, United States of America., Moll FL; Department of Surgery, University Medical Center Utrecht, Utrecht, Netherlands., Murray JC; Department of Pediatrics, University of Iowa, Iowa City, Iowa, United States of America., Musk AW; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia., Nieminen MS; HUCH Heart and Lung Center, Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland., Njølstad I; Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway., Ohlsson C; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Oldehinkel AJ; University of Groningen, University Medical Center, Interdisciplinary Center Psychopathology and Emotion Regulation, Groningen, The Netherlands., Oostra BA; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Palmer LJ; School of Public Health, University of Adelaide, Adelaide, South Australia, Australia; Robinson Research Institute, University of Adelaide, Adelaide, South Australia, Australia., Pankow JS; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, United States of America., Pasterkamp G; Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Penninx BW; Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands., Perola M; Estonian Genome Center, Univeristy of Tartu, Tartu, Estonia; National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Peters A; DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Polašek O; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia., Pramstaller PP; Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany; Department of Neurology, General Central Hospital, Bolzano, Italy., Psaty BM; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America; Departments of Epidemiology and Health Services, University of Washington, Seattle, Washington, United States of America; Group Health Research Institute, Group Health Cooperative, Seatte, Washington, United States of America., Qi L; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America., Quertermous T; Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Rankinen T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America., Rauramaa R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America., Rioux JD; Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec, Canada., Rivadeneira F; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Rotter JI; Los Angeles BioMedical Resesarch Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland., den Ruijter HM; Experimental Cardiology and laboratory of clinical chemistry, UMCU, Utrecht, The Netherlands., Saltevo J; Department of Medicine, Central Finland Central Hospital, Jyväskylä, Finland., Sattar N; BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom., Schunkert H; DZHK (German Centre for Cardiovascular Research), partnersite Munich Heart Alliance, Munich, Germany; Deutsches Herzzentrum München, Technische Universität München, München, Germany., Schwarz PE; Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany., Shuldiner AR; Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America; Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, Maryland, United States of America., Sinisalo J; HUCH Heart and Lung Center, Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland., Snieder H; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands., Sørensen TI; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom; Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, Frederiksberg, Denmark., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom., Staessen JA; Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; R & D VitaK Group, Maastricht University, Maastricht, The Netherlands., Stefania B; Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy., Thorsteinsdottir U; deCODE Genetics, Amgen inc., Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Stumvoll M; University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany; University of Leipzig, Department of Medicine, Leipzig, Germany., Tardif JC; Montreal Heart Institute, Montréal, Québec, Canada; Department of Medicine, Université de Montréal, Montréal, Québec, Canada., Tremoli E; Centro Cardiologico Monzino, IRCCS, Milan, Italy; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy., Tuomilehto J; Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Centre for Vascular Prevention, Danube-University Krems, Krems, Austria; Instituto de Investigacion Sanitaria del Hospital Universitario La Paz (IdiPAZ), Madrid, Spain; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Uitterlinden AG; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Uusitupa M; Department of Public Health and Clinical Nutrition, University of Eastern Finland, Finland; Research Unit, Kuopio University Hospital, Kuopio, Finland., Verbeek AL; Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands., Vermeulen SH; Radboud university medical center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, The Netherlands; Department of Human Genetics, Radboud university medical center, Nijmegen, The Netherlands., Viikari JS; Department of Medicine, University of Turku, Turku, Finland., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Vollenweider P; Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, Lausanne, Switzerland., Waeber G; Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, Lausanne, Switzerland., Walker M; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Institute of Cellular Medicine, Newcastle University, Newcastle, United Kingdom., Wallaschofski H; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Wareham NJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom., Watkins H; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom., Zeggini E; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom., Chakravarti A; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America., Clegg DJ; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America., Cupples LA; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America., Gordon-Larsen P; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United States of America; Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Jaquish CE; National Heart, Lung, and Blood Institute, National Institute of Health, Bethesda, Maryland, United States of America., Rao DC; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America., Abecasis GR; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America., Assimes TL; Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America., Barroso I; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science Addenbrooke's Hospital, Cambridge, United Kingdom; University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science Addenbrooke's Hospital, Cambridge, United Kingdom., Berndt SI; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Boehnke M; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America., Deloukas P; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge, United Kingdom; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Fox CS; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts,United States of America., Groop LC; Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö, Sweden; Finnish Institute for Molecular Medicine (FIMM), Helsinki University, Helsinki, Finland., Hunter DJ; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America., Ingelsson E; Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, United States of America., Kaplan RC; Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York, United States of America., McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom; Oxford NIHR Biomedical Research Centre, Oxford, United Kingdom., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America., O'Connell JR; Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes & Nutrition, Dept of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America., Schlessinger D; National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America., Strachan DP; Population Health Research Institute, St George's, University of London, London, United Kingdom., Stefansson K; deCODE Genetics, Amgen inc., Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., van Duijn CM; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands; Center for Medical Systems Biology, Leiden, The Netherlands., Hirschhorn JN; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, United States of America; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America., Lindgren CM; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Heid IM; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University Regensburg, Regensburg, Germany; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., North KE; Carolina Center for Genome Sciences and Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Borecki IB; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Kutalik Z; Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Social and Preventive Medicine, University Hospital Lausanne (CHUV), Lausanne, Switzerland; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland., Loos RJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Publikováno v:
PLoS genetics [PLoS Genet] 2015 Oct 01; Vol. 11 (10), pp. e1005378. Date of Electronic Publication: 2015 Oct 01 (Print Publication: 2015).
Autor:
Bolton JL; University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom., Hayward C; MRC Human Genetics Unit, Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Direk N; Department of Epidemiology, Erasmus Medical Centre, Rotterdam, The Netherlands., Lewis JG; Canterbury Health Laboratories, Christchurch, New Zealand., Hammond GL; Department of Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, Canada., Hill LA; Department of Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, Canada., Anderson A; University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom., Huffman J; MRC Human Genetics Unit, Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Wilson JF; Centre for Population Health Sciences, Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Campbell H; Centre for Population Health Sciences, Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Rudan I; Centre for Population Health Sciences, Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Wright A; MRC Human Genetics Unit, Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Hastie N; MRC Human Genetics Unit, Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Wild SH; Centre for Population Health Sciences, Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Velders FP; Department of Epidemiology, Erasmus Medical Centre, Rotterdam, The Netherlands., Hofman A; Department of Epidemiology, Erasmus Medical Centre, Rotterdam, The Netherlands., Uitterlinden AG; Department of Epidemiology, Erasmus Medical Centre, Rotterdam, The Netherlands., Lahti J; Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland., Räikkönen K; Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland., Kajantie E; National Institute for Health and Welfare, Helsinki, Finland., Widen E; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Palotie A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland; Department of Medical Genetics, University of Helsinki and University Central Hospital, Helsinki, Finland., Eriksson JG; National Institute for Health and Welfare, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland; Helsinki University Central Hospital, Unit of General Practice, Helsinki, Finland; Folkhalsan Research Centre, Helsinki, Finland; Vasa Central Hospital, Vasa, Finland., Kaakinen M; Institute of Health Sciences and Biocenter Oulu, University of Oulu, Oulu, Finland., Järvelin MR; Institute of Health Sciences and Biocenter Oulu, University of Oulu, Oulu, Finland; Department of Children and Young People and Families, National Institute for Health and Welfare, Oulu, Finland; Department of Epidemiology and Biostatistics, MRC-HPA Centre for Environment and Health, Imperial College London, London, United Kingdom; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., Timpson NJ; MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom., Davey Smith G; MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom., Ring SM; School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom., Evans DM; MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom., St Pourcain B; School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom., Tanaka T; Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, United States of America., Milaneschi Y; Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, United States of America; Department of Psychiatry, VU University Medical Center/GGZ inGeest, Amsterdam, The Netherlands., Bandinelli S; Geriatric Unit, ASF, Florence, Italy., Ferrucci L; Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, United States of America., van der Harst P; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands., Rosmalen JG; University of Groningen, University Medical Center Groningen, Interdisciplinary Center for Psychiatric Epidemiology, Groningen, The Netherlands., Bakker SJ; University of Groningen, University Medical Center Groningen, Department of Internal Medicine, Groningen, The Netherlands., Verweij N; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, The Netherlands., Dullaart RP; University of Groningen, University Medical Center Groningen, Department of Internal Medicine, Groningen, The Netherlands., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Morris A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Ingelsson E; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Anderson LN; Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada., Pennell CE; School of Women's and Infant's Health, The University of Western Australia, Crawley, Australia., Lye SJ; Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada., Matthews SG; Department of Physiology, University of Toronto, Toronto, Ontario, Canada., Eriksson J; Center for Bone and Arthritis Research, Institute of Medicin, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Mellstrom D; Center for Bone and Arthritis Research, Institute of Medicin, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Ohlsson C; Center for Bone and Arthritis Research, Institute of Medicin, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Price JF; Centre for Population Health Sciences, Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Strachan MW; University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom., Reynolds RM; University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom., Tiemeier H; Department of Epidemiology, Erasmus Medical Centre, Rotterdam, The Netherlands., Walker BR; University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Publikováno v:
PLoS genetics [PLoS Genet] 2014 Jul 10; Vol. 10 (7), pp. e1004474. Date of Electronic Publication: 2014 Jul 10 (Print Publication: 2014).