Zobrazeno 61 - 70
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Autor:
Vania Tietsche deMoraes Hungria, Camila Peña, David Gómez‐Almaguer, Humberto Martínez‐Cordero, Natalia Paola Schütz, Vivian Blunk
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 867-878 (2024)
Abstract The incidence of multiple myeloma (MM) has surged globally, particularly in Latin American countries, and is attributable to an aging population and increased life expectancy. This systematic review analyzes the epidemiology, patient charact
Externí odkaz:
https://doaj.org/article/8d8f8092e64748b9906535d1ff45db60
Autor:
Vadim Lesan, Ketevani Melivadze, Johannes Hein, Manfred Ahlgrimm, Stefan Schunk, Moritz Bewarder, Konstantinos Christofyllakis, Joerg Thomas Bittenbring, Lorenz Thurner
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 863-866 (2024)
Abstract Donor‐specific anti‐human leukocyte antigen (HLA) antibodies represent a main cause of primary graft failure specifically in the setting of haploidentical stem cell transplantation. Newer therapy strategies including daratumumab could ov
Externí odkaz:
https://doaj.org/article/74cb23f88fb448ea89f88ae9c42df933
Autor:
Michael J. R. Desborough, Emma Laing, Daphne Kounali, Ana Mora, Renate Hodge, Siobhan Martin, Helen Thomas, Cara Hudson, Joseph Parsons, Akshay Shah, Paula Hutton, Tim Parke, Matthew P. Wise, Matthew Morgan, Stuart McKechnie, Simon J. Stanworth
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 772-777 (2024)
Abstract Thrombocytopenic patients have an increased risk of bleeding when undergoing invasive procedures. In a multicentre, phase II, blinded, randomised, controlled feasibility trial, critically ill patients with platelet count 100 × 109/L or less
Externí odkaz:
https://doaj.org/article/795e0b5869aa48bb8e902ebb8d73db90
Autor:
Erik Boberg, Adrian Kimiaei, Cecilia Karlström, Maria Ljungqvist, Anna Ågren, Maria Bruzelius
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 768-771 (2024)
Abstract Caplacizumab reduces the need for therapeutic plasma exchange (TPE) during treatment for thrombotic thrombocytopenic purpura (TTP), associates with fewer required TPE, and shortens hospital stay. It is therefore recommended as part of standa
Externí odkaz:
https://doaj.org/article/8159520339554fc684e1989b38bad910
Autor:
Yusuke Takada, Shuhei Kurosawa, Toshimitsu Ueki, Yuho Najima, Satoshi Wakita, Hiroki Yamaguchi, Takako Yokota, Masaki Hibi, Ayumi Hirahara, Tsutomu Yoshida, So Okubo, Moe Masuda, Hitomi Nakayama, Aki Sakurai, Chisako Ito, Yoshinobu Aisa, Tomonori Nakazato
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 802-809 (2024)
Abstract Mixed‐phenotype acute leukemia (MPAL) with FLT3‐TKD mutations is a rare and challenging subtype of leukemia. Effective management strategies are crucial for improving patient outcomes. A 31‐year‐old man with FLT3‐TKD‐mutated MPAL
Externí odkaz:
https://doaj.org/article/9e043a80005145d6a962d5851eeb9dd1
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 859-862 (2024)
Abstract Chronic myeloid leukaemia (CML) has been classically described as a disease restricted to the bone marrow with very few reports of extramedullary involvement. CNS involvement with CML has been described in the literature as an aggressive dis
Externí odkaz:
https://doaj.org/article/8fef9ec2802e42cea91579fb14849980
Autor:
Zekarias Seifu Ayalew, Gebeyehu Tessema Azibte, Fisihatsion Tadesse, Biruk Abate Legesse, Zerubabel Getahun Kiflu, Mahlet Tsige Weldeamanuel, Kibrekidusan Aynekulu Tsige, Bereket Abraha Molla, Addisu Melkie Ejigu
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 749-756 (2024)
Abstract Introduction The efficacy of BCR‐ABL tyrosine kinase inhibitors (TKIs) in treating chronic myelogenous leukemia and other malignancies is well‐documented. However, concerns about potential nephrotoxicity have raised questions. This study
Externí odkaz:
https://doaj.org/article/e4e270fb73e6495897f81021eae67875
Autor:
Tomohiro Yabushita, Yoshimitsu Shimomura, Hayato Maruoka, Daisuke Katoh, Daisuke Yamashita, Hironaga Satake, Nobuhiro Hiramoto, Satoshi Yoshioka, Noboru Yonetani, Momoko Nishikori, Takeshi Morimoto, Yukihiro Imai, Takayuki Ishikawa
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 698-708 (2024)
Abstract Somatic hypermutations (SHMs) in the variable region (VH) of the immunoglobulin heavy chain (IgH) gene are common in diffuse large B‐cell lymphoma (DLBCL). Recently, IgH VH SHMs have become known as immunogenic neoantigens, but few studies
Externí odkaz:
https://doaj.org/article/b22f7b1979c24583aac4b6c56dc70b75
Autor:
Chien‐Chin Lin, Chi‐Yuan Yao, Yu‐Hung Wang, Yueh‐Chwen Hsu, Chang‐Tsu Yuan, Tsung‐Chih Chen, Chia‐Lang Hsu, Sze‐Hwei Lee, Jhih‐Yi Lee, Pin‐Tsen Shih, Chein‐Jun Kao, Po‐Han Chuang, Yuan‐Yeh Kuo, Hsin‐An Hou, Wen‐Chien Chou, Hwei‐Fang Tien
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 738-748 (2024)
Abstract Introduction IDH2 mutation is an unfavorable prognostic factor in patients with primary myelofibrosis (PMF) but its effect on myelofibrosis (MF) remains largely unclear. Methods In this study, we aimed to elucidate the roles of IDH2 mutation
Externí odkaz:
https://doaj.org/article/fa92d941b488439f9510b04086ba0152
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 851-854 (2024)
Abstract A 79‐year‐old man presented with respiratory distress associated with a mediastinal mass and pleural effusion, and was diagnosed as having adult T‐cell leukemia/lymphoma. The patient was highly refractory to anticancer drugs and radiot
Externí odkaz:
https://doaj.org/article/ca0569c21fa2473ea839ed05b9925112